<p><strong>Concerns about injecting water into a GC system largely come from older column designs, where stationary phases were simply coated and could be affected by water exposure. Modern capillary columns are typically chemically bonded, which improves resistance to water injections and even supports water rinsing in many cases.</strong></p><p>One practical exception involves <strong>very polar polyethylene glycol </strong>(PEG / “wax”) phases. Because these phases strongly interact with water, repeated aqueous injections can allow water to accumulate and gradually shift selectivity. For many PEG-based columns, minimizing frequent water injections helps maintain consistent performance.</p><p>A separate—and often more important—issue is water’s<strong> very large vapor expansion in a hot inlet</strong>. If the vapor volume exceeds the inlet liner capacity, backflash can occur, sending sample vapor into cooler, unheated zones and increasing the risk of carryover. Using smaller injection volumes helps reduce this risk.</p><p>In workflows where water is the<strong> sample matrix </strong>(for example, volatile analysis), analytes may elute at relatively low oven temperatures while water and higher-boiling residues can linger. Periodic bake-off (high-temperature cleanup steps) is commonly used to restore column performance when water remains on the phase at low temperatures.</p><p>In summary, the biggest hesitation about water injections is rooted in legacy, coated column stories. With chemically bonded phases, the key considerations tend to be inlet expansion/backflash behavior, water retention on very polar phases, and routine maintenance practices like bake-out.</p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1571"><strong>Zebron ZB-WAX</strong><i><strong>PLUS</strong></i><strong> GC Columns</strong></a></h4><ul><li>100% aqueous stable, excellent for aqueous samples; bonded and solvent rinseable</li><li>Extremely inert for acidic compounds</li><li>Enhanced selectivity for low boiling solvents; high retention of alcohols and chlorinated solvents</li><li>Increased efficiency at 20&nbsp;°C</li></ul></blockquote>

Water in GC: Safe or Risky? Here’s What You Need to Know

<p><strong>🎤 Presenter:</strong> <strong>Paul-Albert Schneide </strong>(University of Copenhagen)</p><p>💾 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/paper/32780"><strong>PDF presentation</strong></a></p><h3><strong>Abstract</strong></h3><p><strong>Tensor decomposition methods such as PARAFAC and PARAFAC2 have been proposed for resolving co-elutions, and extracting purified spectra in two-dimensional chromatography datasets. However, the application of these methods is usually restricted to local regions-of-interest (ROIs). Therefore, additional pre-processing steps, are required and processing multiple samples at once can be difficult due to retention time shifts (e.g., it is difficult to define a ROI that captures the same analyse signal in multiple samples).</strong></p><p>This work presents an application of fast, shift-invariant tensor decomposition, which was used for the decomposition of full-scale GCxGC-VUV datasets. The results show that chemical groups can be resolved, which are non-separable with conventional, template-based approaches, such as aliphates and olefines, Furthermore, the extracted peak areas are in good agreement with the quantitative results of the reference methods (e.g., bromine number for olefines).</p><h2><strong>Video Transcription</strong></h2><h3><strong>Background and Motivation</strong></h3><p>The project originated from a collaboration initiated by Alexandra Alvich from IFPEN, who approached Prof. Rasmus Bro’s research group at the University of Copenhagen for help analyzing a GC×GC-VUV dataset acquired during her PhD research. The work was then continued by Paul-Albert Schneider and Jesper Henri from the Technical University of Denmark.</p><p>The primary objective was to develop a simpler and less manually intensive approach for petrochemical group quantification while maintaining strong quantitative performance and spectral interpretability.</p><p>According to Schneider, the proposed method is based on two key principles:</p><ul><li>Simple implementation with a minimal number of tuning parameters</li><li>Accurate estimation of peak patterns, VUV spectra, and peak areas</li></ul><p>The workflow specifically targets group-level petrochemical analysis rather than individual compound identification.</p><h3><strong>Data Analysis Workflow</strong></h3><p>The presented workflow begins with a collection of GC×GC-VUV measurements. In this study, the researchers analyzed:</p><ul><li>14 gas oil samples</li><li>24 total measurements, including replicates</li><li>Samples processed using different treatment methods</li></ul><p>Initial preprocessing was performed using a dedicated plug-in module developed during Alexandra Alvich’s PhD work. The preprocessing included:</p><ul><li>Signal smoothing</li><li>Downsampling</li><li>Basic data conditioning</li></ul><p>The processed data were then submitted to the decomposition engine developed by the Copenhagen research group. The decomposition produced:</p><ul><li>Resolved VUV spectra</li><li>GC×GC chromatographic landscapes</li><li>Peak areas or peak volumes</li></ul><p>An in-house spectral library from IFPEN was subsequently used to verify that the extracted spectra corresponded to known petrochemical groups, enabling group-level quantitative analysis.</p><p>Importantly, the workflow currently requires only a single major tuning parameter: the number of components used in the decomposition model. The researchers also noted ongoing efforts to automate this selection step.</p><h3><strong>Comparison with Existing Template-Based Methods</strong></h3><p>The study benchmarked the new approach against Alexandra Alvich’s previously developed template-based quantification method.</p><p>In the template-based workflow:</p><ul><li>Elution regions are predefined using a grid structure</li><li>Peak intensities within those regions are summed</li><li>Quantitative estimates are obtained for specific petrochemical classes</li></ul><p>Although the template-based strategy demonstrated strong performance compared with other analytical techniques, Schneider highlighted several limitations:</p><ul><li>Sensitivity to retention time shifts</li><li>Manual adjustment of integration regions</li><li>Dependence on prior knowledge of coeluting compounds</li></ul><p>The new decomposition-based method was designed to reduce manual intervention and improve robustness against chromatographic variability.</p><h3><strong>Shift-Invariant Trilinear Decomposition</strong></h3><p>The proposed workflow is conceptually related to PARAFAC and multivariate curve resolution methods.</p><p>One important advantage of GC×GC-VUV data is the applicability of the Beer–Lambert law, which enables mathematically structured decomposition approaches.</p><p>The researchers evaluated two possible strategies:</p><ol><li>Decomposing each sample individually</li><li>Decomposing all samples simultaneously after concatenation into one large dataset</li></ol><p>The second strategy became the central focus of the work. Multiple samples were concatenated into a large matrix and factorized to extract shared chemical information across all measurements simultaneously.</p><p>Unlike many conventional GC×GC deconvolution pipelines, the workflow does not rely on a prior region-of-interest detection step. Instead, the entire dataset is decomposed directly.</p><h3><strong>Addressing Retention Time Shifts</strong></h3><p>A critical challenge for PARAFAC-type models is the assumption of strict trilinearity. In GC×GC datasets, however, second-dimension retention time shifts caused by temperature programming violate this assumption.</p><p>Schneider demonstrated how standard one-component PARAFAC models fail to properly model shifted peaks, leaving characteristic residual patterns. When fitting additional components, conventional models often allocate extra components to describing peak shifts instead of resolving true coeluting compounds.</p><p>The shift-invariant model solves this issue by explicitly accounting for chromatographic shifts. As a result:</p><ul><li>Large shifted peaks are modeled correctly</li><li>Residuals are minimized</li><li>Small coeluting peaks become resolvable</li></ul><p>The algorithm uses fast Fourier transform (FFT)-based operations internally to correct for chromatographic shifts efficiently.</p><p>According to the presentation, the approach is also significantly faster than PARAFAC2, which is commonly used for shifted datasets.</p><p>The researchers additionally described extensions of the model that can accommodate:</p><ul><li>Retention time shifts</li><li>Peak shape variations</li><li>Additional flexibility without losing uniqueness properties</li></ul><h3><strong>Quantitative Results</strong></h3><p>The team applied a seven-component model to the complete dataset containing 24 GC×GC-VUV measurements.</p><p>The decomposition extracted seven characteristic VUV spectra, which were compared against the IFPEN in-house spectral library. The extracted spectra matched known petrochemical group signatures very well.</p><p>The resolved components included:</p><ul><li>Two monoaromatic components</li><li>Two diaromatic components</li><li>Additional petrochemical group patterns</li></ul><p>For quantitative evaluation, chemically related components were grouped together.</p><h4><strong>Reproducibility</strong></h4><p>Replicate measurements demonstrated strong quantitative reproducibility:</p><ul><li>Relative standard deviations below 10%</li><li>Consistent peak area estimation across petrochemical groups</li></ul><h4><strong>Comparison with the Template-Based Approach</strong></h4><p>The decomposition workflow showed good agreement with the existing template-based quantification strategy, with monoaromatics representing the main discrepancy requiring further investigation.</p><p>Schneider explained that the differences were likely related to relative response factor scaling used in the template-based method but not yet implemented in the decomposition workflow at the time of the presentation.</p><h4><strong>Future Development</strong></h4><p>The researchers outlined several next steps for the project:</p><ul><li>Running models on individual samples to achieve higher resolution</li><li>Resolving sulfur-containing compounds</li><li>Extracting more sample-specific differences</li><li>Automating component number selection</li><li>Investigating deviations in monoaromatic quantification</li><li>Integrating the workflow into an open-source software project</li></ul><p>The team also expressed interest in future collaboration with other researchers working on related GC×GC data analysis workflows.</p><h3><strong>Conclusion</strong></h3><p>The presented shift-invariant trilinear decomposition workflow demonstrated promising performance for automated petrochemical group analysis in GC×GC-VUV datasets. By combining robust mathematical modeling with minimal manual intervention, the method offers a simplified alternative to traditional template-based approaches while maintaining strong quantitative agreement and spectral interpretability.</p><p>The work highlights the growing role of advanced multivariate data analysis strategies in comprehensive chromatography and demonstrates how shift-aware decomposition methods can significantly improve the analysis of highly complex petrochemical datasets.</p><blockquote><p><strong>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</strong></p></blockquote>

One-shot tensor decomposition of full-scale GC×GC-VUV datasets for resolving petrochemical groups (Paul-Albert Schneide, MDCW 2026)

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 11th May 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you application note by<strong> Shimadzu, </strong>poster by <strong>MDCW / William &amp; Mary</strong> and brochure by <strong>Thermo Fisher Scientific!</strong></p><h3><strong>1. MDCW / William &amp; Mary: Optimizing Solvent Selection and Data Reduction Workflows for GC×GC Fire Debris Analysis</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/P_14_O_Brien_63304669ee.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><h5><strong>What are Ignitable Liquid Residues (ILRs)?&nbsp;</strong></h5><ul><li>Chemical remains of ignitable liquids (IL) (e.g., gasoline or diesel) that did not fully burn during a fire&nbsp;</li><li>ILRs are usually petroleum-based products and contain complex mixtures of volatile chemicals, like hydrocarbons&nbsp;</li></ul><h5><strong>Forensic Analysis of ILRs&nbsp;</strong></h5><ul><li>Collection of porous materials like wood from the fire’s point of origin&nbsp;</li><li>Must be stored in airtight containers to prevent volatile ILR from evaporation&nbsp;</li><li>Passive headspace extraction onto activate charcoal strips (ACS) is used to extract ILRs from debris, and dichloromethane (DCM) is used to extracts ILRs from charcoal strips&nbsp;</li><li>Emerging is the use of two-dimensional gas chromatography – time of fight - mass spectrometry (GC×GC-TOFMS), with higher separation and resolution</li><li>Resulting chromatograms presents a pattern of peaks which can be used to identified specific type of accelerant used&nbsp;</li></ul><h5><strong>Chemometrics&nbsp;</strong></h5><ul><li>The discipline that focuses on the application of statistical and mathematical methods to analyze chemical data and extract meaningful information (Bovens, 2019)&nbsp;</li><li>Helps make sense of large datasets from analytical instruments, find pattens, and classify samples</li></ul><h4><strong>Methods</strong></h4><h5><strong>Analytical Instrumentation&nbsp;</strong></h5><ul><li>LECO corporation <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1097"><strong>BTX4D GC×GC-TOFMS</strong></a> with <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1289"><strong>Paradigm Shift reverse fill-flush (RFF) flow modulator</strong></a></li></ul><h5><strong>Software&nbsp;</strong></h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1873"><strong>ChromaTOF Sync 2D</strong></a> (LECO corporation)&nbsp;</li><li>R Statistical Software</li></ul><h4><strong>Conclusions</strong></h4><p>This study demonstrated that the use of chemometrics can be integrated into a data processing workflow to better understand data sets and create a streamlined process. Using UMAP, patterns identified that were not originally seen in PCA lead to the preferred solvents of ILR extraction being hexane and methanol. Since UMAP allowed visualization of local and global structures, groupings of gasoline samples allowed for better analysis of solvent effect.</p><h3><strong>2. Shimadzu: Multiresidue Pesticides Analysis in Solvent Extract of Annatto (Natural Color Additive) Using </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-TQ8050+NX"><strong>GCMSTQ8050 NX</strong></a></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_06_sip_gc_043_en_95576a9ac4.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>User Benefits</strong></h5><ul><li>&nbsp;Accurate and reproducible trace level quantitation of pesticides in highly pigmented complex matrix using Ultra-fast GCMSTQ8050 NX and QuEChERS extraction</li><li>Single-laboratory partial validated method for LOQ determination meeting regulatory guidelines</li><li>Ease of instrumental method optimization using GCMS Smart Pesticides Database Ver.2 from Shimadzu Corporation</li></ul><p>Annatto is an orange-red condiment and food colorant derived from the seeds of the achiote tree (Bixa Orellana) (Fig. 1). It is often used to impart a yellow to red-orange color to foods, but sometimes also for its flavor and aroma. Similar effects can be obtained by extracting some of the color and flavor principles from the seeds, which are then added to the food. Annatto and its extracts are now widely used in an artisanal or industrial scale as a coloring agent in many processed food products, such as cheeses, butter, baked goods, potatoes, snack foods, breakfast cereals, smoked fish etc. In these uses, Annatto is a natural alternative to synthetic food coloring compounds.&nbsp;</p><p>Owing to its large culinary uses and other diverse applications, use of chemical pesticides for its production in large quantities is imperative. Dye extraction process may result in concentration of pesticides and in turn contribute to adverse impact on human health when incorporated in various preparations. Hence quantitation of residual pesticides in Annatto extract becomes very important. As the oleoresin is a complex matrix, it is required to develop a rugged, sensitive and efficient method for extraction of residual pesticide and its analysis.&nbsp;</p><p>This study reports a highly sensitive method for simultaneous quantification of multiple pesticides in highly pigmented complex matrix of Annatto using modified QuEChERS[1] with triple quadrupole gas chromatography (GC-MS/MS) system.</p><h4><strong>Materials and Methods</strong></h4><p>For this study, customized reference standard mixture of most commonly observed pesticides in Annatto seeds was procured from Restek Corporation.</p><p>The calibration standards were analyzed from 0.5 to 1000 μg/L. Linearity was plotted by external standard method and using weighted regression of 1/C2. Sample was spiked at 3 levels i.e., 10, 25 and 100 μg/kg. Recovery samples were prepared in 6 replicates at each level. <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMS-TQ8050+NX"><strong>GCMS-TQ8050 NX</strong></a> (Fig. 2), manufactured by Shimadzu Corporation Japan, was used for quantitation. LabSolutions InsightTM was used for data processing, which helped in evaluating validation parameters with ease.</p><h4><strong>Conclusion</strong></h4><p>This study shows that the modified QuEChERS method combined with GC-MS/MS system is a reliable and efficient tool to quantify residual pesticides in Annatto extract sample. Although Annatto extract is a highly pigmented complex matrix, the modified QuEChERS method significantly reduces interference. Also, extremely sensitive Shimadzu GC-MS/MS allows trace level detection even after multifold dilution of sample. This helps in reducing contamination and enhancing ruggednessresulting in reproducible detection of analytes.</p><h3><strong>3. Thermo Fisher Scientific: Sentinel PRO 710 environmental mass spectrometer Precise real time gas analyzer for toxic volatile organic compounds</strong></h3><ul><li>Product specification</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/sentinel_pro_710_spec_sheet_en_886523bfc2.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=3&amp;search=Sentinel+PRO"><strong>Thermo Scientific™ Sentinel PRO Environmental Mass Spectrometer </strong></a>is a highly reliable and versatile gas analyzer ideal for reporting the presence of toxic VOCs from fugitive emissions in industrial settings to ensure worker safety.</p><h4><strong>Fugitive emissions of toxic VOCs&nbsp;</strong></h4><p>Wherever there is potential danger for fugitive emissions of toxic organic vapors from a chemical production unit, regulating authorities often require plants to keep records of ambient vapor concentrations to protect workers from exposure. Various forms of capture include evacuated vessels, organic vapor monitors, or purge and trap devices, all of which require samples to be sent for analysis. Alternatively, electrochemical sensors or open path FT-IR spectroscopy can provide more immediate results. However, none of these technologies are capable of providing the spatial and temporal resolution required to qualify as actionable information.&nbsp;</p><h4><strong>Analytical platform&nbsp;</strong></h4><p>The primary feature of the Sentinel PRO mass spectrometer is the magnetic sector analyzer. This field-proven technology has demonstrated the strongest performance for industrial on-line gas analysis. Magnetic sector technology offers precision, accuracy, long intervals between calibrations. The new touchscreen interface further enhances usability, providing intuitive in-person operation, simplified maintenance, and real-time data viewing. Multi-role user permissions ensure security and control allowing operators to customize settings based on their specific needs.&nbsp;</p><h4><strong>Comprehensive data collection&nbsp;</strong></h4><p>With speed and precision, the Sentinel PRO analyzer monitors all the critical areas for short-term exposure levels of toxic VOCs, and also provides accurate and time-weighted average exposure data. With a high number of sample points available, many can be located close to potential leak points such as valve stems, etc., enabling leak detection and correction before any toxic hazard is created.&nbsp;</p><h4><strong>Membrane inlet mass spectrometry&nbsp;</strong></h4><p>The analyzer is fitted with a membrane inlet to reduce the pressure of the sample air from atmospheric to the working pressure of the enclosed ion source. This allows a method of sample introduction that greatly enhances the system’s sensitivity to VOCs. Since the membrane is more permeable to VOCs than to major air gases, it provides enrichment by several orders of magnitude, enabling detection as low as 5 ppb (species dependent) permits easy membrane replacement during annual routine maintenance to minimize downtime and increase productivity.</p></div></div></div></div></div></div></section>

News from LabRulezGCMS Library - Week 20, 2026

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Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.

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Phenomenex Zebron ZB-35HT Inferno GC Columns

Zebron Inferno column ZB-35HT is the first non-metal, 35 % phenyl column stable to 400 ˚C.

<h4><strong>High Temperature Stability for Mid-Polarity</strong></h4><ul><li>First non-metal, 35 % phenyl columns stable to 400 ˚C</li><li>Longer lifetime with rugged high temperature, polyimide coated, fused silica tubing</li><li>Robust column for high temperature analysis</li><li>Great for high molecular weight compounds</li><li>Eliminate carry-over with high temperature bake outs</li><li>Low activity, provides good peak shape for acidic and basic samples</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_35_HT_Inferno_GC_Column_773b8b1796.webp" alt="Phenomenex: Zebron ZB-35HT Inferno GC Column" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_35_HT_Inferno_GC_Column_773b8b1796.webp 245w," sizes="100vw" width="500" height="150"></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_35_HT_Inferno_79e3acc7c9.jpg" alt="Phenomenex: Zebron™ ZB-35HT Inferno™" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_35_HT_Inferno_79e3acc7c9.jpg 167w," sizes="100vw" width="603" height="564"></p><h4><strong>Recommended Use</strong></h4><p><strong>Intermediate polarity with high temperature stability (up to 400 °C) for:</strong></p><ul><li>high boilers</li><li>contaminants</li><li>carry-overs</li><li>high-temp bakeouts</li></ul><h4><strong>Recommended Applications</strong></h4><ul><li>Amines</li><li>Aroclors</li><li>Chemicals</li><li>Drugs of Abuse</li><li>EPA Methods 508, 608, 8081, 8141, 8151</li><li>Pesticides</li><li>Pharmaceuticals</li><li>Semi-volatiles</li><li>Steroids</li></ul><h5><strong>Alternative to:</strong> Any 35 % Phenyl 65 % Dimethylpolysiloxane Phase:</h5><ul><li>DB®-35ms</li><li>SPB-680</li><li>MDN-35</li><li>DC-35</li><li>Rtx-35&nbsp;</li><li>SPB®-35</li><li>Rtx®-35MS</li><li>007-11</li><li>EC-35</li><li>BPX35</li><li>AT-35</li><li>HP-35ms</li><li>Sup-Herb</li><li>OV-11</li><li>HP-35</li><li>BPX608</li></ul><h3><strong>Phenomenex Zebron Inferno GC Columns</strong></h3><h4><strong>Overcome Traditional Obstacles</strong></h4><h5><strong>Challenge # 1: Short Fused Silica Column Lifetimes</strong></h5><p>Unlike Zebron™ Inferno™ GC columns, traditional fused silica columns are not equipped to handle prolonged exposure to<br>temperatures above 360 °C. At high temperatures, fused silica GC columns:</p><ul><li>Become inflexible and brittle</li><li>Break easily and cause costly replacement</li><li>Require more system downtime for maintenance</li><li>Can’t separate high molecular weight compounds</li></ul><h5><strong>Challenge # 2: Cumbersome Metal Column Tubing</strong></h5><p>Though metal columns have higher temperature limits than capillary columns, they are more difficult to use.</p><p><strong>Most metal columns:</strong></p><ul><li>Are inflexible and hard to use</li><li>Require special tubing cutters for installation</li><li>Are prone to leaks from expansion and contraction</li><li>Have active surfaces, giving poor peak shapes for acids and bases</li><li>Are incompatible with MS detectors</li></ul><h3><strong>How it works</strong></h3><p>Zebron™ Inferno™ columns offer enhanced performance where other columns fail. The two critical factors that allow for this are:</p><ul><li><h5><strong>Advanced ESC™ Bonding Technology</strong></h5></li></ul><p>At high temperature ranges, the stability of standard GC columns deteriorates, resulting in increased bleed. Zebron’s Engineered Self Cross-linking™ (ESC) bonding technology reinforces the stationary phase for enhanced column durability and extremely low bleed levels at high temperatures. <strong>The result:</strong> Inferno columns with the flexibility to perform for high temp oven ramps and bakeouts.</p><ul><li><strong>High Temperature Polyimide Coating</strong></li></ul><p>Standard polyimide resin pyrolyzes at temperatures above 360 °C, making the tubing unstable. Zebron Inferno columns use a temperature resistant polyimide resin that shows minimal thermal degradation, even at temperatures up to 430 °C*. This means longer column lifetime at elevated temperatures.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg" alt="Phenomenex: Zebron Inferno GC Columns - How it works" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_Inferno_GC_Columns_How_it_works_d2d5658adc.jpg 245w," sizes="100vw" width="978" height="564"></p><h3><strong>Features of Zebron Inferno GC Columns</strong></h3><h4><strong>Extremely Low Bleed for Rugged Performance</strong></h4><ul><li>Longer column lifetime</li><li>Better reproducibility</li><li>Maximum sensitivity</li><li>More accurate quantitation</li></ul><h4><strong>Increased Column Lifetime with Enhanced Durability</strong></h4><ul><li>Less instrument downtime</li><li>More productivity</li><li>Lower laboratory costs</li></ul><h5><strong>Standard GC Columns Cannot Withstand High Temperature</strong></h5><p>After prolonged exposure to temperatures above 360 °C, most traditional GC columns become brittle and inflexible, often spontaneously breaking in the middle of a run. Work is stopped in order to change out the column and perform system maintenance. Unlike these fragile columns, ZebronTM InfernoTM columns have a thermally resistant polyimide coating for longer column lifetime at temperatures up to 430 °C. As a result, you get less instrument downtime, and higher productivity.</p><h4><strong>Greater Performance for High Boiling Compounds</strong></h4><ul><li>Better peak shape</li><li>Improved separation</li><li>More analytes detected</li></ul><p>Zebron™ Inferno™ columns have the inertness and temperature stability needed to separate high molecular weight compounds. These high boilers require a thermally rugged column with low bleed levels. Inferno columns provide optimal separation of these analytes.</p>

Phenomenex Zebron ZB-1701 GC Columns

Zebron ZB-1701 Provides alternate selectivity to phenyl phases with similar polarity

<p><strong>Alternate Selectivity for Mid-Polarity Analyses</strong></p><ul><li>Fast run and re equilibration times for enhanced sample throughput and productivity</li><li>Provides alternate selectivity to phenyl phases with similar polarity</li><li>Good peak shape for active analytes</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_1701_75b9286de0.webp" alt="Phenomenex: Zebron ZB-1701" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_1701_75b9286de0.webp 245w," sizes="100vw" width="500" height="150"></p><h5><strong>Recommended Use</strong></h5><ul><li>Alcohols, Amines, Aromatic Hydrocarbons, Drugs, Esters, PAHs, PCBs, Pharmaceutical Intermediates, Phenols, Solvents, Steroids, TMS Sugars, Tranquilizers</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_1701_c2a6145780.jpg" alt="Phenomenex: Zebron ZB-1701" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_1701_c2a6145780.jpg 143w," sizes="100vw" width="634" height="694"></p><p><strong>Upgrade to Zebron from any 14 % cyanopropylphenyl / 86 % dimethylpolysiloxane phase:</strong></p><h5><strong>Agilent®</strong></h5><ul><li>DB®-1701&nbsp;</li><li>CP-Sil 19 CB</li></ul><h5><strong>Restek®</strong></h5><ul><li>Rtx®-1701&nbsp;</li><li>Rtx-VMS&nbsp;</li></ul><h5><strong>SGE®</strong></h5><ul><li>&nbsp;BP10&nbsp;&nbsp;</li></ul><h5><strong>Supelco®</strong></h5><ul><li>SPB®-1701&nbsp;&nbsp;</li><li>Equity®-1701&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</li></ul><h5><strong>OV®</strong></h5><ul><li>OV-1701<br>&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;</li></ul>

Phenomenex Zebron ZB-1701P GC Columns

Zebron ZB-1701P is a guaranteed column for pesticide analysis

<p><strong>Enhanced Response for DDT and Endrin</strong></p><ul><li>Specially tested to ensure response of DDT, Endrin, Endrin Aldehyde, and Endrin Ketone</li><li>Guaranteed column for pesticide analysis</li><li>EPA Method 8081 Certified</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_1701_75b9286de0.webp" alt="Phenomenex: Zebron ZB-1701P" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_1701_75b9286de0.webp 245w," sizes="100vw" width="500" height="150"></p><h5><strong>Recommended Use</strong></h5><ul><li>Aroclors, nitrogen containing pesticides, organochlorine pesticides, organophosphorous pesticides</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_1701_P_c4ccee1802.jpg" alt="Phenomenex: Zebron ZB-1701P" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_1701_P_c4ccee1802.jpg 138w," sizes="100vw" width="657" height="740"></p><p><strong>Upgrade to Zebron from any 14 % cyanopropylphenyl / 86 % dimethylpolysiloxane phase:</strong></p><h5><strong>Agilent®</strong></h5><ul><li>DB®-1701&nbsp;</li><li>DB-1701P</li><li>CP-Sil 19 CB</li></ul><h5><strong>Restek®</strong></h5><ul><li>Rtx®-1701&nbsp;</li><li>Rtx-VMS&nbsp;</li></ul><h5><strong>SGE®</strong></h5><ul><li>&nbsp;BP10&nbsp;&nbsp;</li></ul><h5><strong>Supelco®</strong></h5><ul><li>SPB®-1701&nbsp;&nbsp;</li><li>Equity®-1701&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</li></ul><h5><strong>OV®</strong></h5><ul><li>OV-1701<br>&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;</li></ul>

Phenomenex Zebron ZB-35 GC Columns

Zebron ZB-35 is an intermediate polarity column for high molecular weight analysis

<p><strong>Low Bleed, Intermediate Polarity Selectivity for GC-MS</strong></p><ul><li>Intermediate polarity column for high molecular weight analysis</li><li>Inert to minimize analyte adsorption, improve efficiency, and reproducibility</li><li>More rugged (longer column life) than other polar phases</li><li>Excellent for trace analysis with bleed-sensitive detectors (MS, FID, ECD, NPD)</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_1701_75b9286de0.webp" alt="Phenomenex: Zebron ZB-35" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_1701_75b9286de0.webp 245w," sizes="100vw" width="500" height="150"></p><h5><strong>Recommended Use</strong></h5><ul><li>Amines, Aroclors, Drugs, EPA Methods (508, 608, 8081, 8141, 8151), Pesticides, Pharmaceuticals, Semi-volatiles, Steroids</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_35_dc84d61d90.jpg" alt="Phenomenex: Zebron ZB-35" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_35_dc84d61d90.jpg 174w," sizes="100vw" width="726" height="651"></p><p><strong>Upgrade to Zebron from any 35 % phenyl / 65 % dimethylpolysiloxane phase:</strong></p><h5><strong>Agilent®</strong></h5><ul><li>DB®-35</li><li>DB-35ms</li><li>HP-35</li><li>HP-35ms&nbsp;</li></ul><h5><strong>Restek®</strong></h5><ul><li>Rtx®-35</li><li>Rtx-35ms&nbsp;</li></ul><h5><strong>SGE®</strong></h5><ul><li>&nbsp;BP1</li><li>BPX1-SimDBPX3 BPX608</li></ul><h5><strong>Supelco®</strong></h5><ul><li>SPB®-35</li><li>MDN-35</li><li>SPB-608&nbsp;&nbsp;</li></ul><h5><strong>OV®</strong></h5><ul><li>OV-11<br>&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;</li></ul>

Phenomenex Zebron ZB-624 GC Columns

Zebron ZB-624  is widely used phase to separate volatile organic flavor and fragrance additives and residual solvents in industrial or pharmaceutical products

<p><strong>Robust Results for VOCs and Residual Solvents</strong></p><ul><li>Widely used phase to separate volatile organic flavor and fragrance additives and residual solvents in industrial or pharmaceutical products (OVIs)</li><li>Popular choice for residual solvent testing</li><li>Excellent for US EPA Methods 501.3, 502.2, 503.1, 524.2, 601, 602, 624, 8010, 8015, 8020, 8021, 8240, 8260</li><li>Specifically designed for the separation of volatile organic compounds (VOCs)</li><li>Increased temperature limit speeds run times and re-equilibration</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_5_8ee06754ca.webp" alt="Phenomenex: Zebron ZB-624" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_5_8ee06754ca.webp 245w," sizes="100vw" width="500" height="150"></p><h5><strong>Recommended Use</strong></h5><ul><li>EPA Methods (501.3, 502.2, 503.1, 524.2, 601, 602, 624, 8010, 8015, 8020, 8021, 8240, 8260), Pharmaceuticals, Residual Solvents, Volatile Organic Compounds (VOCs)</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_624_971ffc45e5.jpg" alt="Phenomenex: Zebron ZB-624" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_624_971ffc45e5.jpg 163w," sizes="100vw" width="684" height="655"></p><p><strong>Upgrade to Zebron from any 6 % cyanopropylphenyl / 94 % dimethylpolysiloxane phase:</strong></p><h5><strong>Agilent®</strong></h5><ul><li>DB®-624</li><li>DB-1301</li><li>DB-VRX</li><li>HP-VOC</li><li>CP-1301</li><li>CP-Select 624 CB</li></ul><h5><strong>Restek®</strong></h5><ul><li>Rtx®-624</li><li>Rtx-1301</li><li>Rtx-VMS</li></ul><h5><strong>SGE®</strong></h5><ul><li>BPX624</li></ul><p><strong>Supelco®</strong></p><ul><li>SPB®-624</li><li>SPB-1301</li></ul><p><strong>OV®</strong></p><ul><li>OV-624</li></ul><h5><strong>Zebron GC Column Benefits</strong></h5><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_GC_Column_Benefits_de6be151ef.jpg" alt="Phenomenex: Zebron GC Column Benefits" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_GC_Column_Benefits_de6be151ef.jpg 245w," sizes="100vw" width="1297" height="742"></p><p>&nbsp;</p>

Phenomenex Zebron ZB-XLB GC Columns

Zebron ZB-XLB is an unique, low polarity si-arylene column

<p><strong>Extra Low Bleed</strong></p><ul><li>Unique, low polarity si-arylene column</li><li>Engineered specifically for use with bleed sensitive detectors such as MS</li><li>Provides alternate selectivity to standard 5-type phases</li><li>Often used for confirmation of pesticides, PCBs, or other environmental samples</li><li>Good tool for sample screening to identify unknown contaminants</li></ul><h5><strong>Recommended Use</strong></h5><ul><li>Herbicides / Insecticides, PCBs, Pesticides , Unknown Samples</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_XLB_24bf657d8c.jpg" alt="Phenomenex: Zebron ZB-XLB" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_XLB_24bf657d8c.jpg 145w," sizes="100vw" width="688" height="741"></p><p><strong>Upgrade to Zebron from these similar* phases:</strong></p><h5><strong>Agilent®</strong></h5><ul><li>DB®-XLB</li><li>VF-XMS</li></ul><h5><strong>Restek®</strong></h5><ul><li>Rxi®-XLB</li><li>Rtx®-XLB</li></ul><p><strong>Supelco®</strong></p><ul><li>MDN-12</li></ul><p><strong>*not exact equivalent, selectivity may differ</strong></p>

Thermo Scientific TraceGOLD TG-1301MS GC Columns

Thermo Scientific™ TraceGOLD TG-1301MS GC Columns provide low-bleed, excellent reproducibility and column-to-column consistency

<p><strong>Thermo Scientific™ TraceGOLD TG-1301MS GC Columns provide low-bleed, excellent reproducibility and column-to-column consistency even with sensitive detectors like ECDs and MS.</strong></p><ul><li>Low to mid-polarity phase, 6% cyanopropylphenyl/94% dimethyl polysiloxane</li><li>Long lifetime</li><li>Excellent inertness</li><li>Equivalent to USP G43 phase</li></ul><figure class="image"><img style="aspect-ratio:1336/812;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_1301_MS_GC_columns_3c3a408729/Pragolab-GC-kolona-TraceGOLD-TG-1301MS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD TG-1301MS GC Columns" width="1336" height="812"></figure><h4><strong>Recommended for:</strong></h4><ul><li>Alcohols</li><li>Volatile organics</li><li>Oxygenates</li><li>Residual solvents</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx-1301</li><li>DB-1301</li><li>BP-624</li><li>HP-1301</li><li>HP-624</li><li>SPB-1301</li><li>SPB-624</li><li>VP-1301</li><li>BF-624ms</li><li>CP-1301</li><li>CP-Select 624 CB</li></ul>

Thermo Scientific TraceGOLD™ TG-624 and TG-624SilMS GC Columns

Analyze residual solvents, volatile organic compounds, alcohols, and oxygenates using Thermo Scientific™ TraceGOLD™ TG-624 and TG-624SilMS GC Columns.

<p><strong>Analyze residual solvents, volatile organic compounds, alcohols, and oxygenates using Thermo Scientific™ TraceGOLD™ TG-624 and TG-624SilMS GC Columns. Both phases offer the low to mid polarity phase, 6% cyanopropylphenyl methypolysiloxane.</strong></p><ul><li><strong>TraceGOLD TG-624 GC Columns </strong>provide 90+% resolution of the first six gases in EPA Method 8260 and EPA Method 524.4. These columns are also ideal for EPA Methods 624 and 608.</li><li><strong>TraceGOLD TG-624SilMS GC Columns</strong> provide high thermal stability with maximum temperatures up to 320°C, which is ideal for volatile organics analysis. They are highly inert, providing excellent peak shape for a wide range of compounds.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Trace_GOLD_TG_624_and_TG_624_Sil_MS_GC_Columns_d515fd8ed9.jpg" alt="Thermo Scientific: TraceGOLD™ TG-624 and TG-624SilMS GC Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Trace_GOLD_TG_624_and_TG_624_Sil_MS_GC_Columns_d515fd8ed9.jpg 244w," sizes="100vw" width="650" height="416"></p><h4><strong>Applications:</strong></h4><ul><li>Alcohols</li><li>Volatile organic compounds</li><li>Oxygenates</li><li>Residual solvents</li></ul>

Thermo Scientific TraceGOLD TG-17MS GC Columns

Thermo Scientific™ TraceGOLD TG-17MS GC Columns are particularly suited for GCMS applications that require more polarity than a 5% phenyl column.

<p><strong>Thermo Scientific™ TraceGOLD TG-17MS GC Columns are particularly suited for GCMS applications that require more polarity than a 5% phenyl column.</strong></p><ul><li>Mid-polarity phase of 50% diphenyl/50% dimethyl polysiloxane</li><li>Ideal for confirmational analysis</li><li>Excellent inertness for active compounds such as pesticides</li><li>Very low-bleed ideal for analysis by GCMS<br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1331/817;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_17_MS_GC_columns_ad70df875d/Pragolab-GC-kolona-TraceGOLD-TG-17MS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD TG-17MS GC Columns" width="1331" height="817"></figure><h4><strong>Recommended for:</strong></h4><ul><li>Pesticides and herbicides</li><li>Rosin acids</li><li>Phthalate esters</li><li>Triglycerides</li><li>Sterols</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rxi™-17</li><li>DB-17</li><li>DB-608</li><li>VF-17ms</li><li>CP-Sil 24 CB</li></ul>

Thermo Scientific TraceGOLD TG-1701MS GC Columns

Thermo Scientific™ TraceGOLD TG-1701MS GC Columns feature a mix of cyano and phenyl groups for increased polarity and a different elution order

<p><strong>Thermo Scientific™ TraceGOLD TG-1701MS GC Columns feature a mix of cyano and phenyl groups for increased polarity and a different elution order relative to less polar columns.</strong></p><ul><li>Mid-polarity phase (14% cyanopropylphenyl, 86% dimethyl polysiloxane)</li><li>Fully characterized for long-term reproducibility, column-to-column consistency and low-bleed</li><li>Optimal for confirmation analysis</li><li>Equivalent to USP G46 phase<br><br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1319/817;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_1701_MS_GC_columns_eee6a3200d/Pragolab-GC-kolona-TraceGOLD-TG-1701MS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD TG-1701MS GC Columns" width="1319" height="817"></figure><h4><strong>Recommended for:</strong></h4><ul><li>Alcohols</li><li>Pesticides</li><li>Oxygenates</li><li>PCB cogeners</li><li>Aroclor mixes</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx-1701</li><li>DB-1701</li><li>HP-1701</li><li>SPB-1701</li><li>VF-1701</li><li>CP-Sil 19 CB</li></ul>

Products from category Mid-Polar GC Columns - page 2

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