<p><strong>In this technical tip from </strong><span><strong>Phenomenex</strong></span><strong>, the topic of gas chromatography (GC) column trimming is addressed from a troubleshooting perspective. The key question explored is whether trimming a GC column is necessary and how it impacts chromatographic performance.</strong></p><h3><strong>Why Trim a GC Column?</strong></h3><p>Column trimming is primarily used to <strong>restore chromatographic performance</strong> by removing damaged or contaminated sections, typically located at the column inlet.</p><h5><strong>1. Baseline Bleed, Noise, Ghost Peaks, Poor Peak Shape</strong></h5><ul><li><strong>Cause:</strong> Column contamination</li><li>Removing the contaminated stationary phase at the column entrance helps restore performance.</li></ul><h5><strong>2. Elevated Baseline (Especially at High Temperature)</strong></h5><ul><li><strong>Cause:</strong> Column bleed</li><li>Degradation of the stationary phase due to <strong>oxygen exposure or thermal damage</strong> leads to increased baseline.</li></ul><h5><strong>3. Ghost Peaks (Peaks Without Injection)</strong></h5><ul><li><strong>Cause:</strong> Residual sample or contamination</li><li>Compounds trapped at the beginning of the column can appear as peaks even when no sample is injected.</li></ul><h5><strong>4. Peak Tailing (Asymmetrical Peaks)</strong></h5><ul><li><strong>Cause:</strong> Damaged or contaminated column sections</li><li>These issues result in <strong>adsorption effects or poor flow dynamics</strong>.</li></ul><h5><strong>5. Retention Time Shifts</strong></h5><ul><li><strong>Cause:</strong> Contamination or damage near the inlet</li><li>Although trimming slightly changes retention time, it can correct shifts caused by inlet-side issues.</li></ul><h5><strong>6. Baseline Noise and Spikes</strong></h5><ul><li><strong>Cause:</strong> Particulate matter or degraded stationary phase</li><li>These can lead to <strong>detector instability</strong> and random signal fluctuations.</li></ul><h5><strong>7. Baseline Drift or Wander</strong></h5><ul><li><strong>Cause:</strong> Contamination or oxidized column sections</li><li>Removing these regions stabilizes the baseline.</li></ul><h5><strong>8. Loss of Resolution or Sensitivity</strong></h5><ul><li><strong>Cause:</strong> General column degradation</li><li>Trimming removes the most exposed and damaged portions, effectively <strong>rejuvenating column performance</strong>.</li></ul><h3><strong>How to Trim a GC Column</strong></h3><p>A capillary GC column consists of:</p><ul><li><strong>Polyimide outer coating</strong> (protective layer)</li><li><strong>Fused silica tubing</strong> (fragile but flexible core)</li></ul><h3><strong>Step-by-Step Procedure</strong></h3><h5><strong>1. Scoring the Column</strong></h5><ul><li>Use a <strong>ceramic wafer</strong></li><li>Hold it at an <strong>inclined angle</strong></li><li>Score the polyimide coating <strong>perpendicular to the column</strong></li></ul><h5><strong>2. Breaking the Column</strong></h5><ul><li>Perform a <strong>quick, decisive flick</strong></li><li>This ensures a <strong>clean, square cut</strong></li></ul><h5><strong>3. Inspecting the Cut</strong></h5><p>After trimming, visually inspect the column end.</p><h3><strong>Examples of Column Cuts</strong></h3><h4><strong>Good Cut</strong></h4><ul><li>Clean, <strong>square end</strong></li><li>Ensures proper sealing and connection</li></ul><h5><strong>Bad Cuts</strong></h5><ul><li><strong>Slight Irregularity</strong><ul><li>Small imperfection at the edge</li><li>Can cause <strong>leaks</strong> and <strong>active sites</strong></li></ul></li><li><strong>Poor / Rough Cuts</strong><ul><li>Uneven or jagged edges</li><li>Lead to:<ul><li>Poor connections</li><li>Active sites</li><li>Peak tailing</li></ul></li></ul></li></ul><h2><strong>Conclusion</strong></h2><p>Trimming a GC column is a simple yet effective troubleshooting step. By removing contaminated or damaged sections—especially near the inlet—it can resolve a wide range of chromatographic issues, including baseline instability, ghost peaks, and loss of performance.</p><p>Proper cutting technique is essential to avoid introducing new problems such as leaks or active sites.</p>

Trimming a GC Column: Purpose, Symptoms, and Proper Technique

<h3><strong>We're excited to announce that </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/999"><strong>Clarity Chromatography Software</strong></a><strong> version 10.1.2 is now available!</strong></h3><p><strong>This minor update expands Clarity’s portfolio with new control modules.</strong></p><h4><strong>Newly added Instrument control modules</strong></h4><ul><li>Ecom auxiliary modules</li><li>HTA ICF control modules</li><li>Spark pump</li></ul><h4><strong>Updated Instrument control modules</strong></h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/168"><strong>Ecom</strong></a> HPLC</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/328"><strong>Knauer</strong></a> HPLC</li><li>Spark ICF control modules</li><li>YoungIn Chromass HPLC</li></ul><blockquote><p>For a complete list of module changes, see the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/version_history?product=1"><strong>Changelog</strong></a>. For more info about exciting new features directly in Clarity, explore what was introduced in the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/article/5622"><strong>Clarity 10.1 release highlights</strong></a>.</p><p>Clarity can control <strong>1000+ instruments</strong>; the <a target="_blank" rel="noopener noreferrer" href="https://www.dataapex.com/controls"><strong>list can be previewed here</strong></a>.</p></blockquote><h4><strong>Supported Instruments in Clarity (DataApex) — Quick Guide</strong></h4><p>Clarity Chromatography Software supports a wide range of chromatographs and peripherals via <strong>digital control (DD)</strong> and <strong>analog acquisition (A/D)</strong> using the <strong>Colibrick</strong> module.</p><h5><strong>Gas Chromatographs (GC)</strong></h5><p>Digital integration over LAN/RS232 (many via ICF):</p><ul><li><strong>Agilent</strong>: 5890, 6890, 7890, 8860, 8890, <strong>Intuvo 9000</strong></li><li><strong>Shimadzu</strong>: GC-2010/2014, <strong>Nexis GC-2030</strong></li><li><strong>Thermo Fisher</strong>: TRACE 1300/1310</li><li><strong>PerkinElmer</strong>: Clarus 400–690</li><li>Also supported: <strong>Dani</strong>, <strong>Ellutia</strong>, <strong>Young In Chromass</strong>, <strong>Apix</strong>, <strong>Fuli</strong>, <strong>GOW-MAC</strong> (selected models)</li></ul><blockquote><p>Note: Most Agilent 6890–8890 and Intuvo use <strong>LAN – ICF</strong>.</p></blockquote><h5><strong>HPLC Systems</strong></h5><p>Full system/module control:</p><ul><li><strong>Agilent</strong> 1100–<strong>1290 Infinity II</strong> (ICF)</li><li><strong>Shimadzu</strong> LC-10/20 and <strong>Nexera LC-40</strong></li><li><strong>PerkinElmer</strong> Flexar / NexSAR</li><li><strong>Knauer</strong> Azura / BlueShadow / Smartline</li><li><strong>Hitachi</strong> Chromaster / Primaide</li><li><strong>Young In Chromass</strong> ChroZen series</li><li><strong>Sykam</strong> S500–S600, <strong>Watrex</strong> Streamline, <strong>Hanon</strong> LC7000–7300</li></ul><h5><strong>HPLC Modules (Pumps, Detectors, Ovens, Fraction Collectors)</strong></h5><ul><li><strong>Pumps</strong>: Agilent 1100–1290 families, Knauer, Shimadzu, PerkinElmer, Sykam, SSI, Ecom</li><li><strong>Detectors</strong>: VWD/DAD(PDA)/RID/FLD/ELSD across Agilent, Shimadzu, Knauer, PerkinElmer, Young In Chromass, Ecom, etc.</li><li><strong>Column Ovens</strong>: Agilent G1316x / G7116x, Shimadzu CTO-20/30/40, Knauer CT2.1, PerkinElmer Flexar</li><li><strong>Fraction Collectors</strong>: Knauer FC 6.1, Teledyne FOXY series, Ecom ECF 2096, Waters Fraction Collector II</li></ul><h5><strong>Autosamplers</strong></h5><ul><li><strong>Agilent</strong> GC ALS (7673/7683/7693/8697), HPLC ALS modules (G1313A–G7167C)</li><li><strong>Shimadzu</strong> AOC-20 / AOC-5000+, SIL-10 / SIL-20 / <strong>SIL-40</strong> series</li><li><strong>CTC Analytics PAL</strong>, <strong>HTA</strong> autosamplers, <strong>Spark</strong> Alias/UHPLC, <strong>Knauer</strong> AS 6.1L</li><li><strong>PerkinElmer</strong> Flexar / NexSAR AS</li></ul><h5><strong>Other Devices</strong></h5><ul><li><strong>GC×GC modulators</strong> (e.g., Charles University GC×GC Modulator)</li><li><strong>Valves &amp; switch modules</strong> (Agilent, Knauer, Shimadzu, VICI-Valco)</li><li><strong>Degassers, flow monitors, managers, interfaces</strong></li><li><strong>LC-MS / GC-MS</strong>: Advion Expression CMS, Microsaic 4500 MiD, Markes BenchTOF (and others)</li><li><strong>Balances (EA extension)</strong>: Mettler Toledo, Sartorius</li></ul><h5><strong>Analog Acquisition (Colibrick)</strong></h5><p>A/D support for legacy or analog-output devices:</p><ul><li><strong>GC</strong>: Agilent 5880/4890A, Varian 3xxx/3800/3900, PerkinElmer Clarus series, Thermo TRACE, Shimadzu GC-14/9A, Scion 43x/45x/83xx/85xx, etc.</li><li><strong>HPLC Detectors</strong>: Waters 2487/2489, ESA Corona, Hitachi L-series, JASCO FP/UV, Ecom LCD series, many others</li><li><strong>Elemental &amp; Amino Acid Analyzers</strong>: Carlo Erba/Costech ECS, Biochrom 20/30+</li></ul><p>If you are interested in a <strong>DEMO VERSION</strong>, contact us!</p>

DataApex Clarity Chromatography software 10.1.2 just released!

<p><strong>🎤Jessica Whitehouse</strong></p><p><strong>Haloacetic acids (HAAs) are disinfection byproducts formed when chlorine or bromine reacts with organic matter in water—and some are linked to serious health concerns. In this episode of Concentrating on Chromatography, we sit down with Jessica Whitehouse, MSc student at the University of Calgary, to discuss how she developed a GC-MS method to detect and quantify HAAs in real-world water samples.</strong></p><p>During her undergraduate research at Thompson Rivers University, Jessica tackled a major challenge faced by many academic labs: how to analyze regulated environmental contaminants without access to GC-ECD instrumentation. &nbsp;Using dispersive liquid–liquid microextraction, derivatization, and GC-MS, she built a faster, more accessible workflow—and applied it to tap water, swimming pools, and hot tubs.</p><h4><strong>In this conversation, we cover:</strong></h4><ul><li>What haloacetic acids are and why they matter</li><li>Why standard EPA methods can be difficult for smaller or teaching-focused labs</li><li>How GC-MS can be adapted for HAA analysis</li><li>The challenges of derivatization and temperature program optimization</li><li>Unexpected findings in brominated vs. chlorinated HAAs</li><li>Why pool and hot tub water can show surprisingly high HAA levels</li><li>The excitement (and frustration) of first-time method development</li><li>Advice for undergraduate and early-career analytical chemists</li></ul><p>Jessica also shares how this project led directly to her current MSc research on ozone and nanobubble water disinfection, where she’s now expanding into ion chromatography.</p><p>Whether you work in environmental analysis, chromatography, GC-MS, or are just starting your journey in analytical chemistry, this episode offers practical insight into real lab constraints, method development, and the joy of finding your first analyte peak.</p><h3><strong>Video Transcription</strong></h3><h4><span><strong>Introduction</strong></span></h4><p>Haloacetic acids (HAAs) are an important class of disinfectant byproducts formed when organic matter present in water reacts with chemical sanitizers. Because several HAAs are associated with adverse health effects, their determination remains relevant in environmental and public health analysis. This interview highlights the academic pathway and research experience of Jessica, whose undergraduate work focused on the development of a gas chromatography–mass spectrometry (GC-MS) method for the analysis of HAAs in pool and hot tub water.</p><p>Her project emerged from a combination of academic interest in analytical chemistry, practical experience with water testing, and the constraints of instrument availability in an undergraduate research setting. The resulting workflow illustrates how method adaptation, critical problem-solving, and persistence can enable meaningful analytical research even when standardized methods are not directly accessible.</p><h4><span><strong>Academic Background and Entry into Analytical Chemistry</strong></span></h4><p>Jessica completed a Bachelor of Science in Chemistry with a minor in Physics at Thompson Rivers University in British Columbia. Her interest in analytical chemistry developed during her second year of study, when coursework revealed the quantitative and detail-oriented nature of the discipline. This emphasis on numerical interpretation, precision, and method development aligned strongly with her academic strengths and motivated her to pursue analytical research.</p><p>Her specific interest in water chemistry originated even earlier through practical work in a pool and hot tub store, where she became familiar with routine water testing and the chemical factors influencing water quality. This early exposure led naturally into undergraduate research under the supervision of Dr. Sharon Brewer, whose expertise in water analysis provided an ideal foundation for the project.</p><h4><span><strong>Haloacetic Acids as Disinfectant Byproducts</strong></span></h4><p>Haloacetic acids are a subset of disinfectant byproducts generated when sanitizing agents react with natural organic matter in water. In treated recreational water systems such as pools and hot tubs, disinfectants are essential for microbial control, yet they can also lead to formation of unwanted chemical byproducts. Because some HAAs are considered potentially harmful, their occurrence and concentration warrant analytical attention.</p><p>In this study, both chlorinated and brominated HAAs were of interest. Although the tested water systems were primarily sanitized using chlorine-based products, the occurrence of brominated HAAs emerged as a notable and somewhat unexpected finding.</p><h4><span><strong>Analytical Challenges and Method Selection</strong></span></h4><p>A major challenge in the project was the lack of access to the instrumentation required for the standard EPA-based method initially considered for HAA analysis. The available protocol depended on GC-ECD instrumentation, which was not accessible at the university. This limitation required the development of an alternative strategy based on the instruments available locally.</p><p>GC-MS was selected as the most practical analytical platform. To support this approach, Jessica identified a literature source describing a similar method that could be adapted to her research aims. In parallel, dispersive liquid–liquid microextraction was introduced into the workflow as a means of sample preparation, providing valuable methodological experience beyond the standard undergraduate laboratory curriculum.</p><p>This adaptation illustrates a common reality in academic research: analytical methodology is often shaped not only by ideal regulatory procedures, but also by local instrument access, scheduling limitations, and the practical needs of the researcher.</p><h4><span><strong>Need for Derivatization in GC-MS Analysis</strong></span></h4><p>A central analytical issue was that HAAs are inherently nonvolatile, which makes them poorly suited to direct GC analysis. To enable gas chromatographic separation, derivatization was required to convert the analytes into more volatile derivatives with more favorable boiling characteristics.</p><p>In this method, derivatization with octanol was employed. This modification improved volatility and also generated larger fragments, which aided mass spectral interpretation by making the analyte fragmentation patterns easier to distinguish. Thus, derivatization served both chromatographic and mass spectrometric purposes.</p><h4><span><strong>Optimization of the GC Temperature Program</strong></span></h4><p>Considerable effort was devoted to optimization of the GC temperature program. The main difficulty did not arise solely from the analytes themselves, but from the derivatization reagent. Octanol produced a broad and persistent chromatographic feature, including a significant shoulder extending into later retention times. This complicated separation and increased pressure to keep the method sufficiently short for routine sample throughput.</p><p>Among the analytes, monochloroacetic acid proved especially problematic. Because it differed only subtly in structure and produced overlapping behavior relative to the octanol-derived background, its signal was difficult to isolate confidently. Although chlorine-containing fragments could be observed, precise assignment remained challenging. This difficulty underscores how small structural differences and matrix-related interferences can complicate quantitative GC-MS workflows.</p><h4><span><strong>Method Performance and Practical Advantages</strong></span></h4><p>Although the adapted GC-MS method was developed out of necessity, it also provided practical advantages over the more standardized workflow that had initially been considered. In particular, the derivatization step in the adapted approach required only approximately 10 minutes, whereas the more conventional procedure involved a water bath step lasting around two hours. In addition, the adapted workflow offered shorter overall preparation and analysis timing, allowing batches of samples to be prepared and placed on the autosampler within a normal working schedule.</p><p>From a practical research perspective, this translated into substantially improved laboratory efficiency. The ability to complete derivatization quickly and begin automated sample analysis without extensive delays made the workflow more manageable and better suited to the demands of an undergraduate project.</p><h4><span><strong>Unexpected Findings: Brominated HAAs in Chlorine-Sanitized Systems</strong></span></h4><p>One of the more surprising outcomes of the study was the predominance of brominated HAAs, despite the fact that the investigated pools and hot tubs were sanitized using chlorine-based treatments. Four of the systems relied on sodium chloride electrolysis to generate chlorine species, while others used chlorine-containing puck formulations commonly applied in recreational water treatment.</p><p>Given these conditions, higher levels of chlorinated HAAs might have been expected. Instead, the results suggested a greater abundance of brominated HAAs. A plausible explanation is the presence of bromine-containing impurities in commercial pool and hot tub chemicals. Although such impurities may occur at relatively low levels, they can still influence disinfectant byproduct formation. The observation highlights the importance of considering the full chemical composition of treatment products, not merely their primary declared active ingredients.</p><h4><span><strong>Value of Practical Industry Experience</strong></span></h4><p>Jessica’s prior work in the pool and hot tub industry provided an unusually strong contextual advantage for the project. Because the samples originated from store clients, she had access to detailed information about the chemicals used in each system, including safety data sheets and knowledge of treatment timing. This background significantly strengthened interpretation of the analytical results by linking measured byproducts to known product usage patterns.</p><p>Such integration of practical field knowledge with laboratory analysis represents an important strength in applied environmental chemistry, particularly when studying real-world water systems rather than idealized laboratory samples.</p><h4><span><strong>Scientific Development and Early Research Motivation</strong></span></h4><p>An especially valuable element of the project was the role it played in building research confidence. Jessica described the first successful identification of an analyte peak as a memorable turning point, reflecting the emotional significance of early experimental success in scientific training. In analytical chemistry, where method optimization often involves repeated setbacks and ambiguous data, such moments can be critical in sustaining motivation and reinforcing scientific identity.</p><p>This experience also informed her advice to early-stage researchers: unfavorable or unexpected outcomes still constitute valid results. Negative or imperfect findings remain analytically meaningful and contribute to scientific understanding, provided they are interpreted carefully.</p><h4><span><strong>Connection to Current Research</strong></span></h4><p>Jessica is now working at the University of Calgary on a different project focused on ozone and nanobubble disinfection. Although the analytical platform and immediate research questions have changed, the conceptual connection to her earlier work remains clear. Her experience with disinfectant byproducts and water chemistry directly supported her transition into this new role and helped position her as a strong candidate for research in water treatment-related systems.</p><p>She also expressed interest in expanding her analytical expertise through ion chromatography, which will play a role in her current work. This transition reflects the broader development of an environmental analytical chemist whose work continues to center on water quality, disinfection chemistry, and the analytical tools needed to investigate both.</p><h4><span><strong>Public Health Relevance</strong></span></h4><p>A notable practical implication of the project concerns recreational water safety. Jessica emphasized that pool and hot tub water should not be ingested, a recommendation already widely understood in general terms but further reinforced by her findings. In at least one case, HAA concentrations were reported at levels far above the federal drinking water regulation threshold. While such regulations are designed for potable water rather than recreational water, the comparison nevertheless illustrates the extent to which disinfectant byproducts may accumulate in these environments.</p><p>She also noted that several HAAs are classified as probable human carcinogens, with prolonged exposure linked to serious health concerns. Although occasional accidental ingestion is not equivalent to chronic exposure, the findings reinforce the importance of appropriate hygiene, safe water maintenance practices, and awareness of chemical byproduct formation in recreational systems.</p><h4><span><strong>Conclusion</strong></span></h4><p>This research demonstrates how meaningful analytical chemistry can emerge from a combination of scientific curiosity, practical constraints, and strong mentorship. By adapting a GC-MS workflow for the determination of haloacetic acids in pool and hot tub water, Jessica developed a method that was both workable within local instrument limitations and efficient enough to offer practical benefits over more conventional procedures.</p><p>Beyond the analytical results themselves, the project highlights several broader themes: the value of undergraduate research, the importance of flexibility in method development, the benefit of practical contextual knowledge, and the relevance of environmental analytical chemistry to real-world public health questions. It also shows how early research experiences can shape a long-term scientific trajectory, leading from undergraduate investigation to continued work in water chemistry and disinfection science.</p><blockquote><p><strong>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</strong></p></blockquote><blockquote><h4><strong>Concentrating on Chromatography Podcast</strong></h4><p>Dive into the frontiers of chromatography, mass spectrometry, and sample preparation with host David Oliva. Each episode features candid conversations with leading researchers, industry innovators, and passionate scientists who are shaping the future of analytical chemistry. From decoding PFAS detection challenges to exploring the latest in AI-assisted liquid chromatography, this show uncovers practical workflows, sustainability breakthroughs, and the real-world impact of separation science. Whether you’re a chromatographer, lab professional, or researcher you'll discover inspiring content!</p><p>You can find <strong>Concentrating on Chromatography Podcast </strong>in podcast apps:</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/1wZg67rCjoGju4yhqxI3tL"><strong>Spotify</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/tz/podcast/concentrating-on-chromatography/id1788429185"><strong>Apple podcast</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podscan.fm/podcasts/concentrating-on-chromatography"><strong>podscan</strong></a></li></ul><p>and on <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/@ChromatographyTalk/videos"><strong>YouTube channel</strong></a></p></blockquote>

Detecting Haloacetic Acids in Water with GC-MS

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Since 1991 DataApex develops and manufactures chromatography data stations. DataApex is constantly striving to provide users with efficient and up-to-date tools for chromatography data processing.

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Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.

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Organomation, founded in 1959, designs and manufactures high-quality nitrogen evaporators and extraction systems. Known for innovation and durability, their lab instruments are used globally for efficient sample preparation with strong customer support.

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Thermo Scientific TraceGOLD™ TG-XLBMS GC Columns

Choose Thermo Scientific TraceGOLD™ TG-XLBMS GC Column which offer a low-polarity, low-bleed column suitable for a wide range of applications.

<p><strong>Choose these columns which offer a low-polarity, low-bleed column suitable for a wide range of applications.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Proprietary stationary phase</li><li>Unique selectivity</li><li>Max. temperature: 340/360 °C</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Pesticides</li><li>PCB congeners</li><li>PAH's</li></ul><h4><strong>Application:</strong></h4><ul><li>Aroclor Mixes Analysis</li><li>GC/MS for PCB Congeners</li><li>GC/MS for PAHs</li><li>GC/MS for Aroclor Mixes</li></ul>

Thermo Scientific TraceGOLD™ TG-VRX GC Columns

Thermo Scientific™ TraceGOLD TG-VRX GC Columns provide good resolution and fast analysis times for volatile compounds.

<p><strong>Thermo Scientific™ TraceGOLD TG-VRX GC Columns provide good resolution and fast analysis times for volatile compounds.</strong></p><ul><li>Proprietary stationary phase</li><li>Optimized dimensions for analysis of volatile organic pollutants</li><li>Ideally suited for US EPA Methods 502.2, 524.2, 8021, and 8260</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Volatile organic pollutants</li><li>Aromatics</li></ul><h4><strong>Application:</strong></h4><ul><li>Volatile Organic Pollutants Analysis</li><li>GC/MS for US EPA Method 8021 Compounds</li></ul><h4><strong>Similar to:</strong></h4><ul><li>DB-VRX</li><li>Rtx-VRX</li></ul>

Thermo Scientific TraceGOLD™ TG-VMS GC Columns

Thermo Scientific™ TraceGOLD TG-VMS GC Columns provide good resolution and fast analysis times for volatile compounds.

<p><strong>Thermo Scientific™ TraceGOLD TG-VMS GC Columns provide good resolution and fast analysis times for volatile compounds.</strong></p><ul><li>Proprietary stationary phase</li><li>Optimized dimensions for analysis of volatile organic pollutants</li><li>Ideally suited for US EPA Method 8260B</li><li>Max. temperature: 260 °C</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Volatile organic pollutants</li></ul><h4><strong>Application:</strong></h4><ul><li>Volatile Organic Pollutants Analysis</li><li>GC/MS for US EPA Method 8260B Compounds</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx-VMS</li></ul>

Thermo Scientific TraceGOLD™ TG-OCP I and II GC Columns

Analyze organochlorine pesticides and herbicides with ultralow bleed, superior sensitivity, excellent peak shape using Thermo Scientific™ TraceGOLD™ TG-OCP I and TG-OCP II GC columns.

<p><strong>Analyze organochlorine pesticides and herbicides with ultralow bleed, superior sensitivity, excellent peak shape and the highest levels of reproducibility using Thermo Scientific™ TraceGOLD™ TG-OCP I and TG-OCP II gas chromatography columns.</strong></p><h4><strong>Redefining Your Expectations for Gas Chromatography:</strong></h4><ul><li>Low bleed with excellent signal-to-noise ratio, sensitivity and mass spectral integrity</li><li>Fast analysis time to facilitate full separation of chlorinated pesticides</li><li>Ideal for U.S. EPA methods 8081, 608 and CLP</li></ul><h4><strong>Proprietary Formulation Facilitates Analysis of Difficult Compounds:</strong></h4><ul><li>The acidic nature of the silanol groups prevalent within many GC columns can result in the adsorption of basic compounds, which frequently leads to peak tailing.</li><li>In TraceGOLD GC columns, basic functional groups are bonded onto the column surface to reduce the effects of tailing and improve run-to-run reproducibility and sensitivity.</li></ul><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended Use:</strong></h4><ul><li>Organochlorine pesticides</li><li>Herbicides</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx™-CLPesticides</li><li>Rtx™-CLPesticides2</li></ul>

Thermo Scientific TraceGOLD™ TG-OPP I and II GC Columns

Analyze organophosphorus pesticides with ultralow bleed, superior inertness, and consistent reproducibility using Thermo Scientific™ TraceGOLD™ TG-OPP I and II GC Columns.

<p><strong>Analyze organophosphorus pesticides with ultralow bleed, superior inertness, and consistent reproducibility using Thermo Scientific™ TraceGOLD™ TG-OPP I and II GC Columns. This column's low bleed delivers excellent signal-to-noise ratio, sensitivity, and mass spectral integrity. Expect full separation of organophosphorus pesticides with a fast analysis time. TraceGOLD TG-OPP I and II GC Columns are ideal for U.S. EPA methods 8141A.</strong></p><h4><strong>Redefines Expectations for Gas Chromatography:</strong></h4><ul><li>Low bleed, delivering excellent signal-to-noise ratio, sensitivity and mass spectral integrity.</li><li>Fast analysis time, facilitating full separation of organophosphorus pesticides.</li><li>Ideal for U.S. EPA methods 8141A</li></ul><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended Use:</strong></h4><ul><li>GC/MS for Organophosphorus Pesticides</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx™-OPPesticides</li><li>Rtx™-OPPesticides2</li></ul>

Thermo Scientific TraceGOLD™ TG-PAH GC Columns

Use these thermally stable TraceGOLD TG-PAH GC columns for fast analysis of regulated polycyclic aromatic hydrocarbons (PAHs) in complex food and environmental samples.

<p><strong>Perform rapid analysis of regulated PAHs such as persistent organic pollutants (POPs) in complex food and environmental samples using Thermo Scientific™ TraceGOLD™ TG-PAH GC columns.&nbsp;</strong></p><p>High selectivity and maximum resolution of this capillary silica based column, combined with its unique bonded chemistry, ensure accurate separation of isobaric compounds even at very low concentration levels. The TraceGOLD TG-PAH GC column is regarded as highly robust due to the exceptionally high thermal stability and long life time. Sensitivity is of paramount importance in meeting regulatory standards in the challenging trace analysis.</p><p>Designed for high resolution analysis of polycyclic aromatic hydrocarbons (<strong>PAHs</strong>) in <strong>complex food and environmental samples</strong>.</p><h4><strong>Key benefits</strong></h4><ul><li>Fast analysis of regulated PAHs</li><li>Maximize resolution for critical isobaric PAHs</li><li>Max. temperature of 360°C</li><li>Low column bleed</li></ul>

Thermo Scientific Trace™ TR-1 GC Columns

Use Thermo Scientific Trace™ TR-1 non-polar GC column for method development and analysis of chlorinated and nitroaromatic compounds and environmental samples.

<p><strong>Use the Thermo Scientific™ TRACE™ TR-1 GC column for method development and chlorinated and nitroaromatic compounds and environmental analyses.&nbsp;</strong></p><ul><li>These non-polar phase, 100% dimethyl polysiloxane gas chromatography columns have a high operating temperature.</li><li><strong>Max. temperature: </strong>340/360 °C</li><li><strong>USP Type: </strong>G1, G2, G38</li></ul>

Thermo Scientific Trace™ TR-1MS GC Columns

Use Thermo Scientific Trace™ TR-1MS low bleed nonpolar column for GC/MS environmental analyses that require high temperature and an inert phase.

<p><strong>With low bleed and a maximum operating temperature of 340–360°C, the Thermo Scientific™ TRACE™ TR-1MS column is ideal for all GC/MS applications. The column is particularly well suited for applications such as GC/MS environmental analyses, which require an inert phase that can operate at high temperature.</strong></p><h4><strong>Engineered for Superior Performance:</strong></h4><ul><li>Nonpolar phase, 100% dimethyl polysiloxane</li><li>High operating temperature</li><li>Inert phase suited for environmental analyses</li></ul><h4><strong>Excellent Quality and Reproducibility:</strong></h4><ul><li>Low bleed even at elevated temperatures</li><li>Outstanding robustness for difficult separations</li><li>Reliable and reproducible performance</li></ul><h4><strong>Applications:</strong></h4><ul><li>Chlorinated and nitroaromatic compounds</li><li>GC/MS environmental analyses</li></ul><h4><strong>Recommended For:</strong></h4><ul><li>Phthalates</li><li>Polymers</li><li>Total recoverable petroleum hydrocarbons (TRPHs)</li></ul><h4><strong>Alternative Uses:</strong></h4><ul><li>Chlorinated Aromatics</li><li>Organochlorine Pesticides</li><li>Organophosphorous Pesticides</li><li>PAHs</li><li>Paraffins</li><li>Polywax</li><li>Pyrethroids</li><li>Semivolatiles</li><li>Xylenes</li></ul><h4><strong>Similar To:</strong></h4><ul><li>DB-1</li><li>DB-Petro</li><li>BP1</li><li>HP-1</li><li>HP-1MS</li><li>Rtx™-1</li><li>Ultra-1</li><li>SPB™-1</li><li>SPB™-1 Sulfur</li><li>Petrocol™ DH</li><li>CP-Sil 5CB</li><li>RSL-150</li><li>RSL-160</li><li>ZB-1</li><li>CB-1</li><li>OV™-1</li><li>PE-1</li><li>007-1(MS)</li><li>SP™-2100</li><li>SE-30</li><li>RH-1</li><li>CC-1</li><li>CP-Sil 5CB MS</li><li>VF-1ms</li></ul>

Thermo Scientific TracePLOT™ TG-BOND Q GC Columns

Achieve consistent, reproducible separation of CO2, methane and 02/N2/CO with Thermo Scientific™ TracePLOT TG-BOND Q GC columns 

<p><strong>Achieve consistent, reproducible separation of CO2, methane and 02/N2/CO. Thermo Scientific™ TracePLOT TG-BOND Q GC columns deliver high performance and unsurpassed stability.&nbsp;</strong></p><p>The columns use a nonpolar, 100% divinyl benzene phase, and the particles are incorporated into the walls of the tubing for essentially no particle release. This strong bonding helps prevent damage to detection systems.</p><h4><strong>Applications:</strong></h4><ul><li>C1 to C3 isomers and alkanes up to C12</li><li>Separation of CO2, methane and O2/N2/CO</li><li>Analysis of oxygenated compounds and solvents</li></ul><h4><strong>Similar To:</strong></h4><ul><li>CP-PoraPLOT Q</li><li>Rt™-Q-BOND</li><li>CP-PoraBond Q</li><li>Supel-Q™-Plot</li><li>AT™-Q</li></ul>

Phenomenex Zebron ZB-1XT SimDist GC Columns

Zebron ZB-1XT SimDist columns deliver outstanding reproducibility and up to 70% higher efficiency thanks to Glass Infusion™ technology—ensuring sharper peaks, accurate high-temperature SimDist, and long column lifetime.

<h4><strong>Consistent, Reliable Results for Simulated Distillation</strong></h4><ul><li>Glass Infusion™ technology for higher efficiency and greater column-to-column reproducibility</li><li>Individual QC testing for every column</li><li>Up to 70 % higher efficiency than other columns</li><li>Increased accuracy for high temperature simulated distillation</li></ul><p>Want a flexible fused-silica alternative for SimDist testing? See <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1563"><strong>ZB-1HT-Inferno</strong></a></p><h5><strong>Recommended Use</strong></h5><ul><li>ASTM Methods (D2887, D2887X, D3710, D6352, D7169), Crude Oil, Gasoline Fractions, Petroleum Distillates, Petroleum Fractions, Simulated Distillation, Vacuum Distillates</li></ul><h5><strong>Upgrade to Zebron from any 100 % dimethylpolysiloxane phase:</strong></h5><p><strong>Agilent®&nbsp;&nbsp;</strong>&nbsp;&nbsp;</p><ul><li>DB®-1</li><li>DB-HT SimDis</li><li>DB-PS1</li><li>DB-PS2887</li><li>CP-SimDist</li><li>CP-SimDist UltiMetal</li></ul><p><strong>Restek®</strong></p><ul><li>Rtx®-1</li><li>Rxi®-1HT</li><li>MXT®-1HT SimDist</li></ul><p><strong>SGE®</strong></p><ul><li>BP1</li><li>BPX1-SimD</li></ul><h3><strong>Sharper Peak Shape and Better Efficiency through Uniform Glass Infusion™ Coating Technology</strong></h3><ul><li><strong>Sharper Peaks and Higher Efficiency:</strong><ul><li>Glass Infusion Technology Provides &nbsp; &nbsp;&nbsp;</li><li>Uniform Coating and Minimizes</li><li>Unwanted Activity.</li></ul></li><li><strong>Consistency and Reliability:</strong><ul><li>Zebron Columns are INDIVIDUALLY</li><li>Tested for Better Reproducibility and</li><li>Overall Performance.</li></ul></li><li><strong>Higher Efficiency:</strong><ul><li>Up to 70 % Higher Column Efficiency.</li></ul></li><li><strong>Long Lifetime and Better Results:</strong><ul><li>Improved Resolution of C50/C52 &nbsp; &nbsp;&nbsp;</li><li>Hour after Hour.</li></ul></li><li><strong>Guaranteed:</strong><ul><li>100 % Risk-Free</li></ul></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Zebron_ZB_1_XT_Sim_Dist_GC_Columns_dd3e7f0c32.jpg" alt="Phenomenex: Zebron ZB-1XT SimDist GC Columns" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Zebron_ZB_1_XT_Sim_Dist_GC_Columns_dd3e7f0c32.jpg 146w," sizes="100vw" width="677" height="722"></p><h3><strong>Improved Recovery and Peak Shape</strong></h3><h4><strong>The Benefits of Glass Infusion™ Technology</strong></h4><p>The Zebron ZB-1XT SimDist metal columns employ a new proprietary bonding called Glass Infusion Technology. The Glass Infusion technology starts by depositing a very uniform layer of glass that completely covers the internal metal surfaces of the column. The result is a uniform coating throughout the column.</p><h5><strong>Glass Enclosed</strong></h5><ul><li>Uniform Glass Infusion ensures adequate covering of exposed metal to promote better recovery and peak shape.</li><li>Each Zebron ZB-1XT is individually tested to confirm and ensure excellent reproducibility.</li><li>The uniform glass coating provides a consistent foundation for stationary phase bonding, thus promoting better over-all efficiency and resolution.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Glass_Enclosed_b434ad6540.jpg" alt="Phenomenex: Glass Enclosed" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Glass_Enclosed_b434ad6540.jpg 245w," sizes="100vw" width="709" height="232"></p><h5><strong>Exposed Metal</strong></h5><ul><li>Non-glass infused with exposed metal can cause tailing peaks and sample adsorption.</li><li>Some manufacturers batch test their columns, leading to poor column-to-column reproducibility.</li><li>These exposed surfaces result in abnormal bonding of the stationary phase which affects chromatographic performance, decreases efficiencies, and inconsistent performance between columns.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Phenomenex_Exposed_Metal_00e4466d96.jpg" alt="Phenomenex: Exposed Metal" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Phenomenex_Exposed_Metal_00e4466d96.jpg 245w," sizes="100vw" width="706" height="237"></p>

Products from category Non-polar GC columns focused on GC columns - page 1

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