Thermo Scientific DXR3 Raman Microscope

The Thermo Scientific™ DXR3 Raman Microscope is a modern, easy-to-use point-and-shoot Raman microscope designed to provide faster, more reliable access to Raman data than ever before. Advanced imaging capabilities combined with automated system calibration deliver exceptional stability, reproducibility, and confidence in Raman measurements—even for non-specialist users.

Thanks to Automated X-axis Calibration, the DXR3 system maintains long-term accuracy and reliability while minimizing user intervention. With a flexible choice of lasers and gratings, the DXR3 Raman Microscope is ideally suited for applications across pharmaceutical research, academia, advanced polymers, microplastics, and many other demanding fields.

Thermo Scientific DXR3 Raman Microscope

Key capabilities

• New Particle Analysis functionality for rapid identification and analysis of microparticles
• High-performance confocal Raman microscopy in a robust, fully integrated design
• Fully automated alignment and calibration with no tools or manual procedures required
• Real-time preview, automated fluorescence correction, auto-exposure, and cosmic ray rejection
• System status indicator providing at-a-glance confirmation that the instrument is optimized and ready for data acquisition
• Three-path fine-beam autoalignment to maintain peak performance and sampling integrity
• Active laser power regulation ensuring consistent sample excitation throughout the lifetime of the laser
• Advanced spectrograph design with no moving parts for simplified operation and highly robust detection and calibration
• Pre-aligned, lock-in-place components with automatic recognition and stored alignment, enabling system reconfiguration in seconds
• Interchangeable lasers and components shared across the DXR3 Raman family
• Optional automated polarized Raman spectroscopy for structural information complementary to chemical data
• Add new excitation wavelengths without tools or service engineer intervention

Thermo Scientific DXR3 Raman Microscope

Laser safety

• Microscope independently certified as Class 1 laser safe
  (Note: optional fiber-optic accessories and certain other optional components are Class 3B laser devices and require appropriate laser safety precautions and eyewear)
• Laser is physically blocked from the visual viewing path, preventing eye exposure during sample observation

Validation and compliance

• Complete DQ/IQ/OQ/PQ validation package available, including extensive documentation and automated software protocols
• OMNIC™ D/S software supports compliance with 21 CFR Part 11

Thermo Scientific DXR3 Raman Microscope

Exceptional analytical performance

• Spatial resolution down to 540 nm on ideal samples
• Confocal depth resolution as fine as 1.7 µm on ideal samples
• Full spectral range of 3500–50 cm⁻¹ captured in a single CCD exposure, eliminating stitching artifacts
• Extended spectral range up to 6000 cm⁻¹ available with the 532 nm laser
• Support for multiple excitation lasers: 455, 532, 633, and 785 nm (high-brightness and high-power options)
• Automatic fluorescence correction available for all excitation lasers
• Research-grade Olympus viewing optics
• Automatic intensity correction enabling spectral comparability between instruments and across different excitation lasers
• Multidimensional wavelength calibration ensuring accurate calibration across the entire spectral range
• Proprietary Triplet spectrograph delivering exceptional peak shape and maintaining focus at all wavelengths
• Software-controlled switching between confocal and high-energy collection modes
• Proprietary algorithms for automated cosmic ray rejection and high-quality laser line filters for artifact-free spectra
• Depolarized lasers to eliminate confusing sample orientation effects
• Active laser power monitoring ensures reproducible excitation power over the laser lifetime and after laser replacement
• Optimized gratings for each excitation laser, avoiding performance compromises associated with shared gratings
• Proprietary autoalignment maintains the system in like-new condition
• Smart-Backgrounds technology automatically removes the CCD dark energy profile

Thermo Scientific DXR3 Raman Microscope

Recommended applications

• Forensics – trace evidence analysis and illicit drug identification
• Pharmaceuticals – polymorphism studies, particulate contamination, and diffusion analysis
• Art restoration and conservation – identification and characterization of pigments, resins, glazes, and inks
• Archaeology – characterization of horn, shell, bone, and ceramic artifacts
• Solar materials – silicon crystallinity and photovoltaic material characterization
• Polymers – inclusions, gel defects, weathering effects, laminate layers, and crystallinity
• Failure analysis – characterization of particulates and small surface features
• Gemology – rapid identification of colored stones, differentiation of natural and synthetic diamonds, characterization of inclusions and adulterants
• Nanotechnology – graphene, carbon nanotubes (CNTs), DLC coatings, and other nanostructures
• Academic research – materials science, biological studies, and a wide range of applied research fields

Thermo Scientific DXR3 Raman Microscope

Specification

• Depth (Metric): 68 cm
• Description: DXR3 Raman Microscope
• Electrical Requirements: 100/240 V, 47/63 Hz
• Electronic Records and Signatures: 21CFR Part 11
• For Use With (Application): 
  • Pharmaceutical
  • Microplastics
  • Forensics
  • Polymer/Chemical
  • Petrochemical
  • Material Science
  • Nanomaterials
  • Academia
  • Energy Storage
  • Art Restoration/Conservation
• Height (Metric): 61 cm
• Laser Power: Fine Laser Power Control: Power controlled and reported at samples in 0.1 mW increments
• Model: DXR3
• Operating Temperature Range: 16°C to 27 °C
• Resolution: 
  • Spatial: 1 µm
  • Confocal Depth: 2 µm
• Wavelength Range: 
  • 455 nm
  • 532 nm high brightness
  • 532 nm high power
  • 633 nm high brightness
  • 633 nm high power
  • 780 nm
• Weight (Metric): 66.5 kg
• Width (Metric): 94 cm
• Type: Microscope
• Unit Size: Each