Thermo Scientific DXR3 SmartRaman Spectrometer

Thermo Scientific DXR3 SmartRaman Spectrometer is a highly automated, push-button operated Raman spectrometer designed for routine laboratory analysis. As a dedicated macro-sampling Raman system, it brings the power of Raman spectroscopy to multi-purpose analytical laboratories that require reproducible, accurate results from a reliable, low-maintenance instrument. With minimal sample preparation and fully automated workflows, the DXR3 SmartRaman is well suited for both research and quality control environments.

Key Capabilities

• Direct measurement through containers: analyze samples directly through glass bottles, jars, and vials (clear or colored), as well as through plastic bags.
• Representative sampling of heterogeneous materials: expandable measurement spot size up to 5 × 5 mm.
• High-throughput automation: accessories support automated measurements of well plates, tablet arrays, tubes, and vials.
• Specialized sample cells: support high- and low-temperature measurements as well as electrochemical experiments.
• Remote sampling: optional fiber-optic probes for samples too large to fit in the sample compartment.
• Advanced software tools: automate analysis workflows and transform spectral data into actionable results.

Thermo Scientific DXR3 SmartRaman Spectrometer

High Performance

• Full spectral range from 3500 to 50 cm⁻¹ captured in a single CCD exposure, eliminating stitching artifacts.
• User-adjustable measurement area from 10 µm to 5 mm using Variable Dynamic Point Sampling (VDPS).
• Four excitation wavelengths (455, 532, 633, and 785 nm) that can be changed in less than one minute.
• Automatic fluorescence correction available for all excitation lasers.
• Automatic intensity correction ensures spectra are comparable across instruments and excitation wavelengths.
• Multidimensional wavelength calibration provides accurate calibration across the entire spectral range.
• Patented triple spectrograph delivers excellent peak shape and maintains focus at all wavelengths.
• Patented algorithms for automated cosmic ray rejection and high-quality laser line filters ensure artifact-free spectra.
• Depolarized lasers minimize sample orientation effects.
• Laser Power Regulator continuously monitors laser power and ensures reproducible excitation over the lifetime of the laser.
• Optimized gratings for each laser avoid compromises associated with shared-grating systems.
• Patented autoalignment keeps the system performing in like-new condition.
• Smart-backgrounds technology automatically removes the CCD dark energy profile.

Software and Spectral Databases

• Extensive spectral libraries with more than 16,000 compounds.
• Library search algorithms optimized specifically for Raman data.
• Specta™ search software enables identification of multiple components in a single measurement.
• Macro-building tools allow repetitive actions to be executed with a single button.
• OMNIC™ Array supports automated data collection and analysis for array-based formats such as well plates and tablet arrays.
• Automatic audit trails record all acquisition parameters and processing steps with each spectrum.

Thermo Scientific DXR3 SmartRaman Spectrometer

Ease of Use

• Patent-pending Autoexposure removes guesswork from optimizing exposure time and number of exposures.
• Autofocusing accessories enable effortless switching between different sample types.
• GO-button operation allows walk-up use: place the sample, press a button, and receive a report without interacting with a computer.
• Fully automated alignment and calibration performed by the software—no user decisions required.
• Smart accessories recognition automatically optimizes parameters and alignment when components are changed.

Reliability, Maintenance, and Modularity

• Routine automatic alignment fully controlled by software.
• Automated calibration procedures with software-driven decision making.
• Automatic laser usage tracking for each installed laser.
• Modular design enables flexible purchasing and future expansion without service calls or penalties.
• User-replaceable lasers with SmartLock™ technology ensure reproducible results via automatic alignment and calibration routines.
• Shared components (lasers, gratings, filters, accessories) can be used across multiple instruments; the system stores alignment and calibration parameters for each unique component and applies them automatically upon installation.

Laser Safety and Validation

• Independently certified Class 1 laser safety for the spectrometer.
  (Note: optional fiber-optic probes and certain accessories are Class IIIB laser devices and require appropriate laser safety precautions and eyewear.)
• Complete DQ/IQ/OQ/PQ validation package available, including extensive documentation and automated software protocols.
• OMNIC™ D/S software supports 21 CFR Part 11 compliance.

Recommended Applications

• Forensics: illicit drug identification, high-throughput automated measurements, and infrared ID backup for court proceedings.
• Pharmaceutical analysis: differentiation of polymorphs and salt forms, tablet characterization.
• Gemology: rapid identification of colored gemstones and discrimination between natural and synthetic diamonds.
• Nanotechnology: bulk nanotube characterization and quality control.
• Academic research: materials science, biological studies, and a wide range of applied research fields.

Thermo Scientific DXR3 SmartRaman Spectrometer

Specifications

• Depth (Metric): 69 cm
• Description: DXR3 SmartRaman Spectrometer
• Height (Metric): 46 cm
• Laser Power: 
  • Fine Laser Power: Control Power controlled and reported at samples in 0.1 mW increments
  • Excitation Lasers: 455 nm, 532 nm, 633 nm, 785 nm
• Model: DXR3
• Operating Temperature Range: 16°C to 32 °C
• Optional Accessories: 
  • Universal Platform Sampling Accessory
  • Carousel Autosampler Sampling Accessory
  • 180 Degree Sampling Accessory
• Resolution: 
  • Full-Range Grating: 5.0 cm⁻¹
  • High-Resolution Grating: 2.0 cm⁻¹
• Software Details: OMNIC Software Suite
• Spectral Range: 3500 to 50 cm⁻¹
• Wavelength Range: 
  • Full-Range Grating: 3500 to 50 cm⁻¹
  • High-Resolution Grating: 1800-50 cm⁻¹
• Weight (Metric): 56.7 kg
• Width (Metric): 97 cm
• Type: Spectrometer
• Unit Size: Each