Phenomenex Strata Screen-A Solid Phase Extraction (SPE)

Mixed-Mode Solid Phase Extraction (SPE) Sorbent

Incorporates the hydrophobic selectivity of a C8 phase and strong anion-exchange for the extraction of acidic drugs from biological matrices.

Phenomenex: Strata Screen-A

• Surface Area (m²/g): -
• Separation Mode: Multi-Mode
• Particle Size: 55
• Recommended Use: Extracts acidic drugs from biological matrices

Starting Method

Strata Screen-A Strong Anion-Exchange

• Condition: 1 mL Methanol
• Equilibrate: 1 mL Water
• Load: Pretreated sample
• Wash 1: 1 mL 25mM Ammonium Acetate Buffer, pH 6-7
• Wash 2: 1 mL Methanol, dry under vacuum for 2-5 min
• Elute: 1 mL 5% Formic Acid in Methanol

Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.