Phenomenex Strata Silica (Si-1) Solid Phase Extraction (SPE)

Normal Phase Solid Phase Extraction (SPE)

A polar phase with slight hydrophobic selectivity in reversed phase mode and moderate polar selectivity in normal phase mode.

Phenomenex: Strata-Silica (Si-1)

• Surface Area (m²/g): 550, m²/g, null m²/g, 490 m²/g
• Separation Mode: Normal Phase
• Pore Size: 70
• Particle Size: 55
• Recommended Use: Extraction of polar compounds that are similar in structure

Starting Method

Strata Normal Phase Method

• Condition: IPA/DCM
• Equilibrate: Hexane
• Load: Pretreated sample
• Wash: 5 % DCM in Hexane
• Elute: 1:1 Hexane / DCM or 1:1 Hexane / IPA

Based on 100 mg/1 mL sorbent mass. The above is a convenient starting point for SPE method development, further optimization may be required to tailor the method for your specific extraction needs.