Sample Handling Vials

Importance of the Topic

Reliable sample containment is a critical factor in modern chromatographic and mass spectrometric analyses, directly influencing data integrity, reproducibility and instrument uptime.

Objectives and Overview

This document surveys the Verex product line of autosampler vials, inserts, caps and seals offered by Phenomenex, detailing formats from 8-millimeter to 15-millimeter neck finishes, specialty micro vials, headspace and storage kits. Emphasis is placed on certified quality, lot traceability and compatibility with major HPLC, GC, SFC and MS autosamplers.

Methodology and Instrumentation

Manufacturing Processes and Quality Control:

• High-purity borosilicate glass (USP Type I Class A) produced by high-speed automated forming
• Machine vision inspection for critical dimensions and tolerances
• Annealing at approximately 1200 °F to remove organic residues and enhance glass integrity
• Positive-pressure cleanroom packaging to prevent particulate contamination

Analytical Testing and Traceability:

• Random lot sampling following ANSI standards
• Contamination screening by LC-UV, GC-FID and LC-MS
• Tamper-evident packaging and 100% lot traceability documentation

Main Results and Discussion

Verex vials achieve ultra-low residual volumes (down to <2 µL with specialty inserts) and reliable air-tight, leak-free seals. A variety of neck finishes (8-425, 9-425, 10-425, 11 mm and 13-425) ensure compatibility across a wide range of autosamplers. Specialty options include silanized deactivated glass, amber coloration, polypropylene for biocompatibility and mass spectrometry certified screw caps for low extractables.

Benefits and Practical Applications

• Improved reproducibility through elimination of ghost peaks and trace contaminants
• Reduced instrument downtime with precision-formed vials and ready-to-use assembled kits
• Enhanced workflow flexibility for routine analysis and high-sensitivity detection
• Streamlined vial selection aided by a detailed autosampler compatibility chart

Future Trends and Applications

Anticipated advances include further miniaturization for nano- and microflow systems, development of advanced low-bleed polymers and coatings, integration of smart tracking (RFID or barcode) for sample chain of custody, and increased automation in sample loading to support high-throughput and remote laboratory operations.

Conclusion

Phenomenex Verex autosampler vials and closures deliver certified, lot-traceable quality and broad instrument compatibility, establishing a robust solution for reliable, high-performance chromatographic and mass spectrometric workflows across research, QA/QC and industrial applications worldwide.