Quick Start Guide to TurboVap LV

Importance of Evaporation in Sample Preparation

The control of solvent evaporation is a critical step in analytical workflows, ensuring consistent sample concentration prior to chromatographic or mass spectrometric analysis. Rapid, uniform and safe removal of solvents from multiple samples enhances throughput, reproducibility and data quality in research, QA/QC and industrial laboratories.

Objectives and Overview of the TurboVap LV Quick Start Guide

This guide provides a concise procedure to familiarize users with the key functions of the TurboVap LV solvent evaporation system. It covers initial setup, operation modes, control panel navigation and recommended daily practices to achieve efficient evaporation of sample tubes in racks of up to 48 positions.

Methodology and Instrumentation

Operation relies on precise control of temperature, gas flow and nozzle positioning to accelerate evaporation while preventing sample loss. Core components include:

• TurboVap LV main unit with integrated water bath and touch-screen interface
• Interchangeable manifolds supporting up to 48 nozzle positions
• Nozzle rack assemblies with end-point detection capability
• Compressed inert gas supply (e.g. nitrogen) regulated via flow control

Users select one of three modes—Manual, Timed or Method—which dictate how and when evaporation terminates. Settings for bath temperature (°C/°F), gas flow (L/min), sound level, screen brightness and sleep behavior are adjusted directly on the display.

Main Procedures and Discussion

Daily preparation involves verifying gas supply, bath water level and instrument settings. Sample racks are placed into the preheated bath, nozzles aligned and secured to avoid contact with tubes. During a run, elapsed and remaining times are monitored on screen; individual nozzle rows can be paused, resumed or disabled as needed. Continuous end-point mode allows replacing completed tubes without restarting the full run. Post-run recommendations include leaving the lid open to prevent moisture buildup and shutting off gas and power when idle.

Benefits and Practical Applications

• High throughput evaporation of up to 48 samples in parallel
• Accurate temperature and gas flow control for reproducible concentration
• Modular nozzle setups accommodate various tube sizes and rack formats
• Automated end-point detection minimizes risk of over-drying highly volatile analytes

Future Trends and Potential Developments

Advancements may include enhanced automation with programmable methods, remote monitoring via network connectivity, integration with LIMS systems and adaptive control algorithms to optimize evaporation profiles for a wider range of solvents and sample matrices.

Conclusion

The TurboVap LV Quick Start Guide equips analysts with the essential steps to operate the evaporation system efficiently and safely. By following standardized setup and operational procedures, laboratories can achieve consistent sample preparation while reducing operator intervention and potential sample loss.

Reference

Biotage. TurboVap LV Quick Start Guide. 2020.