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Low-Level Quantification of NDMA and Non-Targeted Contaminants Screening in Drinking Water Using GC-Orbitrap MS

 

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APPLICATION NOTE Authors: Cristian Cojocariu,1 Maria José Farré,2 Sara Insa,2 Damià Barceló2,3 and Paul Silcock1 Thermo Fisher Scientific, Runcorn, UK; 2Catalan Institute 1 for Water Research (ICRA), Parc Científic i Tecnològic de la Universitat de Girona, 17003 Girona, Spain; 3Institute…
Key words
ndma, ndmadrinking, drinkingwater, waterexactive, exactivedcm, dcmsamples, samplesquantification, quantificationmass, masscontaminants, contaminantsusing, usingdetection, detectionscreening, screeningsolvent, solventrepeatability, repeatabilitywere
Cristian Cojocariu,1 Maria Jose Farre,2 Sara Insa,2 Damia Barcelo,2,3 and Paul Silcock1 1 Thermo Fisher Scientific, Runcorn, UK 2 Catalan Institute for Water Research (ICRA), Parc Científic i Tecnològic de la Universitat de Girona, 17003 Girona, Spain 3 Institute of…
Key words
ndma, ndmadcm, dcmexactive, exactivenitrosodimethylamine, nitrosodimethylamineflask, flaskdetection, detectionmass, massppb, ppbdata, dataquantification, quantificationdrinking, drinkingusing, usingidl, idlrepeatability, repeatabilitychromatography
CASE STUDY 73263 Overcoming the challenges of nitrosamine impurities in drugs What pharmaceutical QA/QC laboratories need to know: Advanced GC-MS capabilities for cGMP nitrosamine testing Why we need to analyze nitrosamine impurities in drugs Unacceptable levels of nitrosamine impurities were…
Key words
min, minndma, ndmandea, ndeanitrosamine, nitrosamineneipa, neipatime, timetemperature, temperatureimpurities, impuritiesorbitrap, orbitrapaquisition, aquisitionmass, massexactive, exactivesource, sourceloop, loopkpa
Overcoming the challenges of nitrosamine impurities in drugs
2020|Thermo Fisher Scientific|Technical notes
CASE STUDY 73263 Overcoming the challenges of nitrosamine impurities in drugs What pharmaceutical QA/QC laboratories need to know: Advanced GC-MS capabilities for cGMP nitrosamine testing Why we need to analyze nitrosamine impurities in drugs Unacceptable levels of nitrosamine impurities were…
Key words
min, minndma, ndmandea, ndeanitrosamine, nitrosamineneipa, neipatime, timetemperature, temperatureimpurities, impuritiesorbitrap, orbitrapmass, massaquisition, aquisitionexactive, exactivesource, sourceloop, loopkpa
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