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Analysis of Residual Solvents – Class 1, Class 2A, Class 2B – in Pharmaceuticals Using Headspace-GC/MS

 

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APPLICATION NOTE 10676 Routine-grade performance of a new static headspace autosampler for the analysis of residual solvents according to USP <467> method Authors Giulia Riccardino1, Paolo Magni2, Stefano Pelagatti2, Manuela Bergna2, Davide Bressanello2, and Cristian Cojocariu1 Thermo Fisher Scientific, Runcorn,…
Key words
xylene, xyleneresidual, residualsolvents, solventstetralin, tetralinprocedure, procedurechlorobenzene, chlorobenzenepharmaceutical, pharmaceuticalaccording, accordingtoluene, tolueneaspirin, aspirinnitromethane, nitromethanechloroform, chloroformmethycyclohexane, methycyclohexanepyridine, pyridinetetrahydrofuran
USP<467> residual solvents
2018|Agilent Technologies|Applications
Application Note Pharmaceuticals USP<467> residual solvents Applying the Agilent 5977A MSD with the Agilent 7697A headspace sampler and Agilent 7890B GC Authors Roger L. Firor and Mike Szelewski Agilent Technologies, Inc. 2850 Centerville Rd Wilmington, DE 19808-1610 USA Abstract The…
Key words
vial, vialheadspace, headspacesolvents, solventsresidual, residualloop, loopacquisition, acquisitiontetralin, tetralintetrahyrofuran, tetrahyrofurannitromethane, nitromethanesim, simcounts, countsmethylcyclohexane, methylcyclohexanepressure, pressureusp, uspxylene
LAAN-C-XX-E038 Application Note No. 56 Analysis of Volatile Hazardous Air Pollutants and Ozone Precursors Using the Cryofocusing GC-MS/MS (MRM) Method Yasuji Watanabe *1, Akira Suzuki *2 Environment Environment 1. Introduction Environmental monitoring of volatile organic compounds in the atmosphere has…
Key words
unit, unitmrm, mrminterference, interferencesubstance, substancedrift, driftunknown, unknownpseudo, pseudodichlorobenzene, dichlorobenzenelow, lowbaseline, baselinesim, simchloride, chloridecyclopentane, cyclopentanepinene, pinenexylene
Application News No. AD-0228 ❑ Pharmaceuticals / HS-20 GC-2030 Analysis of Residual Solvents in Pharmaceutical Products by Headspace-GC-FID with Nitrogen Carrier Gas Following USP<467> - Procedure B Introduction USP <467> monograph describes Procedure A and B for analysing residual solvents…
Key words
nitrogen, nitrogenratio, ratiocarrier, carrierfid, fidgas, gaspharmaceutical, pharmaceuticalsolvents, solventsprocedure, procedurexylene, xylenepeak, peakresidual, residualnews, newsheadspace, headspacemethylbutyylketone, methylbutyylketonetemperature
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