AAPS 2024 PHARMSCI 360
AAPS 2024 PharmSci 360 will take place October 20-23, 2024, in Salt Lake City, UT.
Registration
Registration Pricing
Full Conference Registration includes access to the scientific sessions, access to the Solution Center (exhibit hall), and entry to the Welcome and Closing Receptions
Early Registration (Received On/Before – Aug. 27, 2024)
Member Rates
- Full Conference: $998
- Student/Post-Doc* (Membership Required): $275
- 1-Day Pass (Mon/Tues/Wed): $520
Non-Member Rates
- Full Conference: $1,498
- 1-Day Pass (Mon/Tues/Wed): $750
Speakers Rate (Please contact [email protected] for instructions)
- Full Conference: $550
- Presentation Day Only: $0
Exhibits & Networking Pass (Exhibit Hall, Posters & Career Development)
- All Three Days: $325
- 1-Day Pass (Mon/Tues/Wed): $175
Advance Registration (On/After Aug. 28 – Sept. 24, 2024)
Member Rates
- Full Conference: $1,198
- Student/Post-Doc* (Membership Required): $285
- 1-Day Pass (Mon/Tues/Wed): $640
Non-Member Rates
- Full Conference: $1,698
- 1-Day Pass (Mon/Tues/Wed): $850
Speakers Rate (Please contact [email protected] for instructions)
- Full Conference: $550
- Presentation Day Only: $0
Exhibits & Networking Pass (Exhibit Hall, Posters & Career Development)
- All Three Days: $350
- 1-Day Pass (Mon/Tues/Wed): $200
On-Site Registration (On/After Sept. 25, 2024)
Member Rates
- Full Conference: $1,398
- Student/Post-Doc* (Membership Required): $295
- 1-Day Pass (Mon/Tues/Wed): $750
Non-Member Rates
- Full Conference: $1,898
- 1-Day Pass (Mon/Tues/Wed): $975
Speakers Rate (Please contact [email protected] for instructions)
- Full Conference: $550
- Presentation Day Only: $0
Exhibits & Networking Pass (Exhibit Hall, Posters & Career Development)
- All Three Days: $375
- 1-Day Pass (Mon/Tues/Wed): $225
*Student / Post-Doc Rate: In order to receive the student / post-doc rate for PharmSci 360, you must be an AAPS student or post-doc member. If you are not a current member, please join or renew your membership before you begin registering. Please allow 24 hours before proceeding with your registration. AAPS audits the list of those registered for PharmSci 360 as students and postdoctoral fellows and may contact these individuals to request verification of their eligibility for the reduced registration fee. Eligibility is based on an individual’s ability to provide suitable documentation.
2024 Scientific Themes and Descriptions
Discovery and Basic Research
Theme 1: Leveraging AI in the Processes of Drug Discovery, Lead Validation, Preclinical Development, and Regulatory Submissions
Keywords: Artificial Intelligence (AI), Bioinformatics, Drug Discovery, Drug Repurposing, Machine
Learning (ML), Metabolomics, Predictive Network Analysis, Proteomics, Regulatory Guidelines, Target
Identification.
Theme 2: Challenges and Opportunities Associated with Targeted Therapeutics
Keywords: Antibody-Drug Conjugates, Cancer, Drug Delivery, Infectious Diseases, Intracellular Signaling, Molecular Pharmacology, Neurological Diseases, Precision Medicine, Targeted Therapeutics, Transporters, Receptor-Mediated Transcytosis.
Theme 3: Innovative Methodologies for Advancing Therapeutics from Bench to Bedside
Keywords: DNA Microarray, Drug Metabolism, Drug Transport, Imaging Modalities, Large Molecule Drugs, Organ-on-a-Chip, Pharmacokinetics, Single-Cell Technologies, Small Molecule Drugs
Preclinical, Clinical, and Translational Sciences
Theme 1: Translating the Translational Sciences - Different Understanding, Common Aim
Keywords: Translation, Preclinical Pharmacology, Clinical Development, Biomarkers, Patient Outcome.
Theme 2: Making Data Work for Us – Applying and Combining Empirical (AI/ML) and Mechanistic Modeling in the Preclinical, Clinical, and Post-Approval Realms
Keywords: Modeling and Simulation, PBPK/QSP, Mechanistic Models, Empirical Models, AI/ML, Digital
Biomarkers.
Theme 3: Advancing Vaccine Development: Utilizing the Power of Model-Based Approaches
Keywords: Model informed drug development, vaccines, immunogenicity prediction, dose optimization,
QSP, real world data
Bioanalytics
Theme 1: Bioanalytical Lab Innovations
Keywords: Automation, Artificial Intelligence (AI), Machine Learning (ML), High Throughput, Assay
Design, Predictive Outcomes, Devices, Platforms, Supply Chain, GLP, GCP, Clinical, Drug Development,
Troubleshooting, Validation, Bioanalytical, Therapeutic, Robotics, Cut-Point Analysis.
Theme 2: Current Challenges in Bioanalytical Labs
Keywords: PK, PD, ADA, APA, NAb, Assays, Immunogenicity, PCR, Molecular, RT-PCR, dd-PCR, ELISPOT, Potency Assays, Domain Specificity, CAR-T, Cross-Validation, Biodistribution, Cell and Gene Therapy, ADCs, AOCs, Oligonucleotides, RNA Therapeutics, Biologics, Multidomain Therapeutics, Critical Reagents, Genomics, Stability, Matrices, Surrogate, LCMS, LBA, Troubleshooting, Microsampling, Con-Conforming Modalities, Cut-Point Analysis.
Theme 3: Regulatory Implications for Bioanalysis
Keywords: PCR, Molecular, RT-PCR, dd-PCR, ELISPOT, Domain Specificity, CAR-T, Cross-Validation, LCMS, LBA, Study Design and Implementation, Cell and Gene Therapy, Immunogenicity, Gaps, Regulatory, Biomarkers, Clinical, Assays, Rare Diseases, Animal Models, Alternate Animal Models, Microsampling, Sample Logistics (China HGRA).
Manufacturing and Analytical Characterization
Theme 1: Innovation in Pharmaceuticals/Biopharmaceuticals Manufacturing and Characterization
Keywords: Continuous manufacturing, single use technologies, modality agnostic flex facilities, green chemistry, sustainability, collaborative ecosystems, smart manufacturing, bioprocessing innovation, pharmaceutical manufacturing 4.0, EU regulatory reform, cross-industry collaborations, disruptive innovation, industry-academia collaboration, federal funding for innovation, digital replicas, predictive modeling, ICH Q12 and Q 14, capillary zone electrophoresis, isoelectric focusing, ion exchange, size exclusion (SEC), reversed phase (RP) or hydrophilic interaction liquid chromatography (HILIC), coupled with ultraviolet (UV), fluorescence, or mass spectrometric (MS), LC MS/MS, SEC-MS, Drug release and dissolution.
Theme 2: Digital Tools to Accelerate Drug Development, Manufacturing and Analysis
Keywords: Automation and Robotics, Simulation And Modeling Platforms To Increase Efficiency, Virtual Testing And Process Design, Digital Twins, Mini Piloting, Platform Ecosystem For DS and DP, Line of Sight to Commercialization, Predictive Modeling for Manufacturing, Supply Chain Visibility (Enhanced Traceability And Visibility), Internet Of Things (IOT) Devices, Real-Time Data Collection, Analysis and Decision Making, Training Simulations Using Virtual Reality (VR) and Augmented Reality (AR), Drug Repurposing -- Artificial Intelligence (AI) and Machine Learning (ML) to Identify New Uses, Regulatory Guidance For Digital Tools, Validation Of Digital Tools, Model Maintenance, Safeguards for Digital Tools.
Theme 3: Challenges and Lessons Learned in Commercializing (Manufacturing and Product Quality Analysis) Novel Modalities
Keywords: Commercialization of Antibody-Drug Conjugates (ADC), Nano-Medicine, Protein Degradation Therapies (PROTACS), Cell Therapy, CRISPER, Bispecifics, Oral Peptide, RNA-Based Therapies, mRNA, SiRNA, Antisense Oligonucleotides, Gene Therapy, Phage Therapy, 3D Printing In Drug Delivery, mRNA Vaccines, Abuse Deterrent Formulations, Life Cycle Management of Analytical Methods, Regulatory Strategy, Intellectual Property Protection, Manufacturing Scalability, Cost of Goods and Manufacturing (COGM) Considerations, Long Term Sustainability and End to End (E2E) Product Lifecycle Management.
Formulation and Delivery
Theme 1: Formulation Approaches to Overcome Development Challenges Across Modalities
Keywords: Modelling, Modality-Specific Formulation Development, Stability and Prediction, Processes and technologies, Quality by Design (QbD).
Theme 2: Turbocharging Drug Product Development: The Critical Role of Excipients
Keywords: Novel Excipients, Advanced Applications of Traditional Excipients, Material Properties, Physicochemical and Biological Properties, Supply Chain Management, Sustainability, Quality and Regulatory Compliance, Impurities.
Theme 3: Advanced Drug Delivery Technologies for Targeted Therapeutics
Keywords: Targeted Drug Delivery, Controlled Release, Site and Disease-Specific Drug Delivery, Long-Acting Therapeutics, Nanomedicine, Drug-Device Combination, Patient Centricity, Target Product Profile.
Career Development
Theme 1: Elevate your Scientific Career with Strong Business Acumen
- Mastering the Art of Contract Negotiation
- Safeguarding Intellectual Property in the Evolving Scientific Landscape
- Unveiling the Secrets in Job Offers: Pharmaceutical Science Career Acceleration
- Securing Resources for Innovations: A Business-Centric Approach for Academic Professionals
- Decoding Stock Options: A Strategic Approach for Pharma Professionals
- Investor Relationship Management: Navigating Objectives Effectively
- Crafting Successful Inter-Company Collaborations in Pharma (In-licensing, Mergers, Acquisitions, Co-Developed Assets)
- Entrepreneurship Unleashed: Initiating Your Venture
- Securing Venture Capital for Start-ups: Strategies for Success
Theme 2: Nurturing a Sense of Equity and Inclusion to Build a Diverse Workforce
- Cultivating Meaningful Diversity to Enrich a Workforce
- Navigating Unconscious Bias: Strategies for Understanding and Inclusive Decision-making
- Promoting Mental Health and Wellness in a Competitive and Diverse Work Environment
- Effective Communication for Diverse Teams: From Listening to Using Inclusive Languages, to Building a Diverse and Successful Team
- Strategies for Work-life Balance for a Diverse and Successful Team
- Role of Mentorship in Building and Nurturing a Diverse and Successful Workforce
- Creating a safe environment to foster new ideas and innovations.
- Develop Intelligence for Effective Cross-Cultural Collaboration
Selection from the Program
Opening Plenary: Panel Discussion on Research Integrity
- Sunday, October 20, 2024
- 5:00 PM – 6:30 PM MT
- Grand Ballroom A-J
Plenary Speaker(s)
- Ivan Oransky, MD (Co-Founder Retraction Watch, New York, New York)
- Brian Nosek, Ph.D. (Co-founder and Executive Director Center for Open Science Charlottesville, Virginia)
- Colby Vorland, Ph.D. (Assistant Research Scientist Indiana University School of Public Health-Bloomington Bloomington, Indiana)
Moderator(s)
- Lynn Kamen, Ph.D. (Scientific Officer and Executive Director BioAgilytix Durham, North Carolina)
Closing Plenary: AI and AI-assisted Approaches in Pharmaceutical Discovery and Development
- Wednesday, October 23, 2024
- 4:15 PM – 5:30 PM MT
- Grand Ballroom A-J
Plenary Speaker
- Piet van der Graaf, Pharm.D., Ph.D. (SVP and Head of QSP, Certara Certara Radnor, Pennsylvania)
Keynote lectures
Monday, October 21, 2024 1:30 PM – 2:30 PM MT
- Accelerating Formulation Development via Machine Learning and Automation
- Christine Allen, PhD (Professor, University of Toronto, Toronto, Ontario, Canada)
- Applying AI/ML Methodologies Within Regulated Bioanalysis
- Mary Belfast (Associate Director, Specialty Bioanalytics, Automation Teva Branded Pharmaceutical Products, Inc., West Chester, Pennsylvania)
- Bioanalytical Lab in the Era of AI and Revolutionary Technologies
- Mark Ma, PhD (VP, Head of Translational Clinical Sciences Biotech, New Haven, Connecticut)
- From Theory to Therapy: Charting the Course from the Lab to Global Health Outcomes in Translational Sciences
- Brian Corrigan, PhD (Unaffiliated Pfizer, Lyme, Connecticut)
- Takeaways from Translational Science Sharpshooters: Simple Strategies for Accuracy, Efficiency, and Impact
- Sam Raney, Ph.D. (Associate Director for Science, US Food and Drug Administration, Silver Spring, Maryland)
- Transitioning Novel Modalities from Exploratory to Patient Centered Medicinal Products: Development Approaches to Maximize Value
- Sachin Mittal, PhD (Executive Director, Pharmaceutical Sciences & Clinical Supplies, Merck & Co., Inc., New Jersey)
- Unveiling Potential: A SWOT Analysis of Innovation in Manufacturing and Analytical Characterization
- Rodolfo Pinal, Ph.D. (Purdue University West Lafayette, Indiana)
- Zero Waste Sustainable Pharmaceutical Manufacturing
- Shweta Singh, PhD (Associate Professor, Purdue University, West Lafayette, Indiana)
- Drug Discovery and Repurposing in the LLM (Large Language Model) Era
- Tudor Oprea, MD, PhD (CEO, Expert Systems Inc, San Diego, California)
Tuesday, October 22, 2024 1:30 PM – 2:30 PM MT
- Isoform-Selective Inhibition of Hsp90 Affords New Opportunities to Treat Cancer, Diseases of the CNS, and Glaucoma
- Brian Blagg, PhD (University of Notre Dame)
- ADC: Drug Development Challenges- What We are Measuring and What Does it Matter?
- Malaz Abutarif PhD (DSI)
- Digital Transformation: A Look Ahead at Unlocking Productivity
- Kevin Macias (Doctor of Philosophy – Eli Lilly)
- Keynote: Digital Transformation: A Paradigm Shift in Pharmaceutical Manufacturing
- Mohan Boggara PhD (Sanofi)
- Using AI/ML What is Lacking to Make AI/ML Really Successful in the Drug Discovery/Development Processes
- Aleksander Mendyk, MSc, PhD, DSc, Professor (Chair and Department of Pharmaceutical Technology and Biopharmacutics, Faculty of Pharmacy, Jagiellonian University - Medical College)
- Purposeful Bioanalysis: Ask the Why and What Questions
- Boris Gorovits, PhD (Regeneron)
- Recent Focus and Landscape Maneuvering of Excipients in Pharmaceutical Formulations
- Mansoor A. Khan, PhD (he/him/his) (Texas A&M University)
- The Importance of Excipient Quality and Development: New Frontiers for Use in Medicines
- Catherine Sheehan, DRSc. MS. MS. (U.S. Pharmacopeia (USP))
- Harnessing the Power of Synergy: How AI and Scientific Analytics Together Deliver Breakthrough Medicines
- Joga Gobburu, PhD, MBA (University of Maryland)
- Impact of Immunogenicity on Gene Therapy Development – Science, Regulatory and Patients
- Jim McNally, PhD (BioAgilytix)
- Challenges with New Modalities: Hitting the Stride from Day 1
- Jennifer Chadwick, PhD (Jennifer Chadwick)
- Effective Drug Development Requires Rationales, Not Rules – Rethinking Guidance for Industry
- Lauren Stevenson, PhD (she/her/hers) (Immunologix Laboratories)
- Innovation Through Advanced Manufacturing: What We Can Learn From the Future
- Xiaoming Xu, PhD (he/him/his) (US Food and Drug Administration)
- Materials and Protein Engineering to Counter Inflammation and Autoimmunity
- Jeffrey A. Hubbell, PhD (he/him/his) (University of Chicago)
- Model Informed Vaccine Development (MIVD) – Challenges and Opportunities
- Mindy Magee, PharmD (she/her/hers) (Clinical Pharmacology Modeling & Simulation, Infectious Diseases and Vaccines, Precision Medicine, GlaxoSmithKline)
- Modelling Prion Neurodegeneration in Human Brain Organoids; Can We Increase the Possibility of Therapeutic Success?
- Cathryn Haigh, PhD (NIAID, NIH)
