James Little - Mass Spec Interpretation Services
James Little - Mass Spec Interpretation Services

My name is James Little and my private consulting company is Mass Spec Interpretation Services. I contract for NIST, Wiley, and Sapec. Previously, I was a Research Fellow specializing in mass spectrometry at Eastman Chemical Company in Kingsport, TN and retired in early 2016 after >37 years of service. For 2017-2019, I did NMR as a limited service employee specializing in end group determinations for Eastman.

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures. All the technical information on my web page was approved as technical session handouts, conference presentations, workshops, journal publications, courses, etc. for distribution outside Eastman. Other postings on this site are my own and do not necessarily represent Eastman’s positions, strategies or opinions. I also include a “little” information about my sailing experiences.

In 2017, I purchased a used Model S85 Tesla and starting to participate in electric vehicle events. In addition, I am a member of the choir at St. Paul’s Episcopal Church, play competitive duplicate bridge, and race sailboats on Watauga Lake.

 

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Processing EI GC-MS Data in Chromatogram Window NIST26
Article | Academy

Processing EI GC-MS Data in Chromatogram Window NIST26

Learn how to process EI GC-MS data in NIST 26 using integrated AMDIS deconvolution, library searching, filtering, spectral review, and Excel reporting for confident compound identification.
James Little/Mass Spec Interpretation Services
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Configuring and Navigating Chromatogram Window NIST26
Article | Academy

Configuring and Navigating Chromatogram Window NIST26

Learn how to configure, customize, and navigate the new NIST 26 Chromatogram Window. This practical guide covers layouts, zooming, filtering, structure display, and efficient data review workflows.
James Little/Mass Spec Interpretation Services
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Wrote about us

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News from LabRulezGCMS Library - Week 43, 2024
Article | Application

News from LabRulezGCMS Library - Week 43, 2024

This week we bring you applications by Agilent Technologies, Thermo Fisher Scientific, and Shimadzu and a presentation by James Little - Mass Spec Interpretation Services!
LabRulez
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RI Calibration in NIST26 Chromatogram and Applying to Calculating RI in Samples

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
GC/MSD, Software
Manufacturer
Wiley
Industries
Other

Processing of Accurate Mass GC-MS with NIST26 Chromatogram

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
Software
Manufacturer
Wiley
Industries
Other

Raw Data Files for EI Low Resolution in the Identifications Folder

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
Software, GC/MSD
Manufacturer
Wiley
Industries
Other

Lib Search: Similarity EI Hybrid Search for Spectra Sent from Chromatogram Window

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
Software, GC/MSD
Manufacturer
Wiley
Industries
Other
 

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Alcohol Determination of Sanitizer Gel Using Nexis GC-2060

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