James Little - Mass Spec Interpretation Services
James Little - Mass Spec Interpretation Services

My name is James Little and my private consulting company is Mass Spec Interpretation Services. I contract for NIST, Wiley, and Sapec. Previously, I was a Research Fellow specializing in mass spectrometry at Eastman Chemical Company in Kingsport, TN and retired in early 2016 after >37 years of service. For 2017-2019, I did NMR as a limited service employee specializing in end group determinations for Eastman.

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures. All the technical information on my web page was approved as technical session handouts, conference presentations, workshops, journal publications, courses, etc. for distribution outside Eastman. Other postings on this site are my own and do not necessarily represent Eastman’s positions, strategies or opinions. I also include a “little” information about my sailing experiences.

In 2017, I purchased a used Model S85 Tesla and starting to participate in electric vehicle events. In addition, I am a member of the choir at St. Paul’s Episcopal Church, play competitive duplicate bridge, and race sailboats on Watauga Lake.

 

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Lib Search: Cleaning Up Workspace and Temporary HLM Files in NIST26clean up
Article | Academy

Lib Search: Cleaning Up Workspace and Temporary HLM Files in NIST26clean up

Learn how NIST MS Search stores library search history, what HLM files are used for, and how to automatically remove temporary files to keep your workspace clean and organized.
James Little/Mass Spec Interpretation Services
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Raw Data Files for EI Low Resolution in the Identifications Folder
Article | Academy

Raw Data Files for EI Low Resolution in the Identifications Folder

Discover what the NIST Identification Folder contains during low-resolution EI GC-MS processing. Learn how TIC, ELU, FIN, TSV, RUN, and LOG files support deconvolution and library searching.
James Little/Mass Spec Interpretation Services
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Wrote about us

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News from LabRulezGCMS Library - Week 43, 2024
Article | Application

News from LabRulezGCMS Library - Week 43, 2024

This week we bring you applications by Agilent Technologies, Thermo Fisher Scientific, and Shimadzu and a presentation by James Little - Mass Spec Interpretation Services!
LabRulez
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Library

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Lib Search: Similarity EI Hybrid Search for Spectra Sent from Chromatogram Window

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
Software, GC/MSD
Manufacturer
Wiley
Industries
Other

Processing of Accurate Mass GC-MS with NIST26 Chromatogram

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
GC/MSD, Software
Manufacturer
Wiley
Industries
Other

RI Calibration in NIST26 Chromatogram and Applying to Calculating RI in Samples

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
GC/MSD, Software
Manufacturer
Wiley
Industries
Other

Configuring and Navigating Chromatogram Window NIST26

Presentations
| 2026 | James Little/Mass Spec Interpretation Services
Instrumentation
GC/MSD, Software, GC/MS/MS
Manufacturer
Wiley
Industries
Other
 

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