We present the combination of Vac-SPME and MC-SPME into Vac-MC-SPME, along with the enhanced separation capability provided by GC×GC and advanced tile-based data handling.

We aim to simplify complex data to elucidate high-level mechanisms of engineering processes using non-targeted (NT) analysis by two-dimensional gas chromatography coupled with mass spectrometry (GCxGC-MS).

This work aimed to verify compliance and validate the performance of two-dimensional gas chromatography coupled to mass spectrometry in different laboratories by monitoring probe metabolites in exhaled breath.

Two-dimensional gas chromatography (GC×GC) methodology, with dedicated sample preparation techniques, has been applied to investigate lipid fractions - total fatty acid profile and minor lipid components.

In the first, part we will summarize why GC×GC has not yet become established in the pharmaceutical field. In the second part, we will present how GC×GC-HRMS was used to investigate the active API.

Development of a low solvent consuming sample preparation for the analysis of xenobiotics in vegetable oils using cryogenic-modulation GC × GC combined with QqQMS

Identification of prehistoric adhesives on stone tools is valuable as it might reveal something about tool use and human behaviour.

In the present study, the volatile organic compounds (VOCs) of pistachio from different geographic origins, were evaluated using a high-capacity concentration (HCC) tool, named HiSorb™, was used.

The performances of GC-TOFMS and GC×GC-TOFMS are compared for in-depth flavour profiling and differentiation of lager beers.

Due to GC×GC’s unique capabilities for delivering separations of complex mixtures of small, organic molecules, it is no surprise that it is a key technology for the agrifood industry.