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James Little/Mass Spec Interpretation Services
James Little/Mass Spec Interpretation Services
My main interest is the identification of organic compounds by mass spectrometry in organic mixtures.
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Effective Use of EI Mass Spectral Databases in Unknown Identifications - Part VII: Tracking Complex Coelution with AMDIS and NIST Search

Th, 24.10.2024
| Original article from: Mass Spec Interpretation Services/James Little
This series of webinars will demonstrate the use of the NIST software suite including the NIST Search, AMDIS, and MS Interpreter for searching EI libraries.
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  • Photo: James Little: Effective Use of EI Mass Spectral Databases in Unknown Identifications - Part VII: Tracking Complex Coelution with AMDIS and NIST Search
  • Video: james little: Forensic@NIST2022 Workshop: Case Study #2 (Tackling Co-elution) – Gary Mallard

NIST, Wiley, and user-created EI mass spectral libraries are very powerful tools for the identification of organic compounds in complex mixtures by gas chromatography-mass spectrometry (GC-MS).  This series of webinars will demonstrate the use of the NIST software suite including the NIST Search, AMDIS, and MS Interpreter for searching EI libraries. The series should be useful to a wide variety of research and developmental scientists involved in medical, environmental, industrial, forensic, and biological disciplines.

The webinars demonstrate both Versions 3.0 (2023) and V2.4 of the NIST search. If you are using V3.0, start with Part 0. If you are using V2.4, start with Part I.

Today, we will look at:

Part VII:  Tracking Complex Coelution with AMDIS and NIST Search

Gary Mallard presented an excellent talk at the Forensic@NIST 2022 Workshop that demonstrated the use of both AMDIS and the NIST Search for identifying unknowns in coeluting GCMS peaks.

I have included the following links to his talk and associated resources. It discusses several more advanced approaches.

Detailed Handouts including tables of content are available in the LabRulezGCMS library

Other parts of this series are focused on:

Higher quality videos can be downloaded here:

Other Webinar Resources:

James Little/Mass Spec Interpretation Services
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