GCMS
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike
Author
The Multidimensional Chromatography (MDC) Workshop
The Multidimensional Chromatography (MDC) Workshop
The Multidimensional Chromatography (MDC) Workshop draws experts in this exciting field to share and discuss their research.
Tags
Presentation
Video
Logo of LinkedIn

Non-destructive identification of prehistoric adhesives by HS-GC×GC-TOFMS (Anika Lokker, MDCW 2023)

Th, 18.1.2024
| Original article from: The Multidimensional Chromatography (MDC) Workshop
Identification of prehistoric adhesives on stone tools is valuable as it might reveal something about tool use and human behaviour.
Video placeholder
  • Photo: Non-destructive identification of prehistoric adhesives by HS-GC×GC-TOFMS (Anika Lokker, MDCW 2023)
  • Video: LabRulez: Anika Lokker: Non-destructive identification of prehistoric adhesives by HS-GC×GC-TOFMS (MDCW 2023)
  • 🎤 Presenter: Anika Lokker¹, Pierre-Hugues Stefanuto², Ronè Oberholtzer², Dries Cnuts², Veerle Rots², Jean-François Focant² (¹University of liège, liège, Belgium. ²University of liège, Liège, Belgium)

Abstract

Identification of prehistoric adhesives on stone tools is valuable as it might reveal something about tool use and human behaviour. Currently, prehistoric glues are chemically analysed by gas chromatography coupled to mass spectrometer (GC-MS) which requires extraction and derivatization of the residues¹.

This is a major drawback as it is destructive for the glue and often, the required amount is not present. Moreover, the adhesives cover a wide range of materials (e.g., resin,animal glue, gum). Therefore, sensitive, universal, and non-destructive identification methods are needed. Headspace solid phase micro-extraction (HS-SPME) in combination with GC-MS and with comprehensive GC-time-of-flight mass spectrometer (HS-SPME-GCxGC-TOFMS) has been proposed²´³.

HS-SPME requires no extraction and derivatization, it is therefore a good opportunity for the chemical identification of prehistoric glues. Moreover, GCxGC-TOFMS has more peak capacity and is more sensitive than GC-MS³. But sensitivity remains a problem, therefore we investigated a different headspace method; dynamic headspace (DHS) coupled to GCxGC-TOFMS.

The DHS method is optimized and validated via design of experiment on pine resin and hide glue. Subsequently, the method is tested on several different adhesives and compared to SPME-GCxGC-TOFMS.

(1.) D. Cnuts, K. A. Perrault, P. H. Stefanuto, L. M. Dubois, J. F. Focant, and V. Rots, Archaeometry, 2018, 60, 1361.
(2.) M. Regert, V. Alexandre, N. Thomas, and A. Lattuati-Derieux, J. Chromatogr. A, 2006, 1101, 245.
(3.) K. A. Perrault, P. H. Stefanuto, L. Dubois, D. Cnuts, V. Rots, and J. F. Focant, Separations, 2016, 3, 8.

The Multidimensional Chromatography (MDC) Workshop
Logo of LinkedIn
 

Related content

Enhanced calibration precision: Leveraging RSE and WLS for optimal function optimization

Technical notes
| 2025 | Thermo Fisher Scientific
Instrumentation
Software
Manufacturer
Thermo Fisher Scientific
Industries

Extractable Pollutants from Microplastics to Vegetables: Incorporation to the Food Chain

Applications
| 2025 | Agilent Technologies
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Agilent Technologies
Industries
Environmental

Analysis of Aldehydes, Benzene, and Limonene in Recycled Polyethylene Terephthalate

Applications
| 2025 | Agilent Technologies
Instrumentation
GC/MSD, GC/SQ, HeadSpace
Manufacturer
Agilent Technologies
Industries
Energy & Chemicals

Analyzing Various Plastics - Benefits of Bundled KnowItAll® Software

Applications
| 2025 | Shimadzu
Instrumentation
Microscopy, RAMAN Spectroscopy, FTIR Spectroscopy
Manufacturer
Shimadzu
Industries
Materials Testing

GC/MS Analysis of Fluorophosphates as Decomposition Products in Lithium Battery Electrolyte

Applications
| 2024 | Shimadzu
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Shimadzu
Industries
Energy & Chemicals
 

Related articles

Pavel Plevka: I only give my team colleagues projects that I would be happy to work on myself
Article | Scientists

Pavel Plevka: I only give my team colleagues projects that I would be happy to work on myself

Virologist Pavel Plevka, two-time ERC grant holder at CEITEC MU, seeks new team members. He discusses virus research, team leadership, and opportunities for students and postdocs.
CEITEC
tag
share
more
A Winning Lab
Article | Science and research

A Winning Lab

A Winning Lab - Chemistry professor receives new lab equipment that expands research capacity and student training.
William & Mary
tag
share
more
News from LabRulezGCMS Library - Week 7, 2025
Article | Application

News from LabRulezGCMS Library - Week 7, 2025

This week we bring you application and technical notes by Agilent Technologies, Thermo Fisher Scientific and Shimadzu!
LabRulez
tag
share
more
Natural Gas Analyser B - Quick Reference Guide
Article | Product

Natural Gas Analyser B - Quick Reference Guide

The NGA (System B) is a standard turnkey system designed for analysing natural gas and de-methaniser hydrocarbon matrices.
ChromSolutions
tag
share
more
 

Related content

Enhanced calibration precision: Leveraging RSE and WLS for optimal function optimization

Technical notes
| 2025 | Thermo Fisher Scientific
Instrumentation
Software
Manufacturer
Thermo Fisher Scientific
Industries

Extractable Pollutants from Microplastics to Vegetables: Incorporation to the Food Chain

Applications
| 2025 | Agilent Technologies
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Agilent Technologies
Industries
Environmental

Analysis of Aldehydes, Benzene, and Limonene in Recycled Polyethylene Terephthalate

Applications
| 2025 | Agilent Technologies
Instrumentation
GC/MSD, GC/SQ, HeadSpace
Manufacturer
Agilent Technologies
Industries
Energy & Chemicals

Analyzing Various Plastics - Benefits of Bundled KnowItAll® Software

Applications
| 2025 | Shimadzu
Instrumentation
Microscopy, RAMAN Spectroscopy, FTIR Spectroscopy
Manufacturer
Shimadzu
Industries
Materials Testing

GC/MS Analysis of Fluorophosphates as Decomposition Products in Lithium Battery Electrolyte

Applications
| 2024 | Shimadzu
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Shimadzu
Industries
Energy & Chemicals
 

Related articles

Pavel Plevka: I only give my team colleagues projects that I would be happy to work on myself
Article | Scientists

Pavel Plevka: I only give my team colleagues projects that I would be happy to work on myself

Virologist Pavel Plevka, two-time ERC grant holder at CEITEC MU, seeks new team members. He discusses virus research, team leadership, and opportunities for students and postdocs.
CEITEC
tag
share
more
A Winning Lab
Article | Science and research

A Winning Lab

A Winning Lab - Chemistry professor receives new lab equipment that expands research capacity and student training.
William & Mary
tag
share
more
News from LabRulezGCMS Library - Week 7, 2025
Article | Application

News from LabRulezGCMS Library - Week 7, 2025

This week we bring you application and technical notes by Agilent Technologies, Thermo Fisher Scientific and Shimadzu!
LabRulez
tag
share
more
Natural Gas Analyser B - Quick Reference Guide
Article | Product

Natural Gas Analyser B - Quick Reference Guide

The NGA (System B) is a standard turnkey system designed for analysing natural gas and de-methaniser hydrocarbon matrices.
ChromSolutions
tag
share
more
 

Related content

Enhanced calibration precision: Leveraging RSE and WLS for optimal function optimization

Technical notes
| 2025 | Thermo Fisher Scientific
Instrumentation
Software
Manufacturer
Thermo Fisher Scientific
Industries

Extractable Pollutants from Microplastics to Vegetables: Incorporation to the Food Chain

Applications
| 2025 | Agilent Technologies
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Agilent Technologies
Industries
Environmental

Analysis of Aldehydes, Benzene, and Limonene in Recycled Polyethylene Terephthalate

Applications
| 2025 | Agilent Technologies
Instrumentation
GC/MSD, GC/SQ, HeadSpace
Manufacturer
Agilent Technologies
Industries
Energy & Chemicals

Analyzing Various Plastics - Benefits of Bundled KnowItAll® Software

Applications
| 2025 | Shimadzu
Instrumentation
Microscopy, RAMAN Spectroscopy, FTIR Spectroscopy
Manufacturer
Shimadzu
Industries
Materials Testing

GC/MS Analysis of Fluorophosphates as Decomposition Products in Lithium Battery Electrolyte

Applications
| 2024 | Shimadzu
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Shimadzu
Industries
Energy & Chemicals
 

Related articles

Pavel Plevka: I only give my team colleagues projects that I would be happy to work on myself
Article | Scientists

Pavel Plevka: I only give my team colleagues projects that I would be happy to work on myself

Virologist Pavel Plevka, two-time ERC grant holder at CEITEC MU, seeks new team members. He discusses virus research, team leadership, and opportunities for students and postdocs.
CEITEC
tag
share
more
A Winning Lab
Article | Science and research

A Winning Lab

A Winning Lab - Chemistry professor receives new lab equipment that expands research capacity and student training.
William & Mary
tag
share
more
News from LabRulezGCMS Library - Week 7, 2025
Article | Application

News from LabRulezGCMS Library - Week 7, 2025

This week we bring you application and technical notes by Agilent Technologies, Thermo Fisher Scientific and Shimadzu!
LabRulez
tag
share
more
Natural Gas Analyser B - Quick Reference Guide
Article | Product

Natural Gas Analyser B - Quick Reference Guide

The NGA (System B) is a standard turnkey system designed for analysing natural gas and de-methaniser hydrocarbon matrices.
ChromSolutions
tag
share
more
 

Related content

Enhanced calibration precision: Leveraging RSE and WLS for optimal function optimization

Technical notes
| 2025 | Thermo Fisher Scientific
Instrumentation
Software
Manufacturer
Thermo Fisher Scientific
Industries

Extractable Pollutants from Microplastics to Vegetables: Incorporation to the Food Chain

Applications
| 2025 | Agilent Technologies
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Agilent Technologies
Industries
Environmental

Analysis of Aldehydes, Benzene, and Limonene in Recycled Polyethylene Terephthalate

Applications
| 2025 | Agilent Technologies
Instrumentation
GC/MSD, GC/SQ, HeadSpace
Manufacturer
Agilent Technologies
Industries
Energy & Chemicals

Analyzing Various Plastics - Benefits of Bundled KnowItAll® Software

Applications
| 2025 | Shimadzu
Instrumentation
Microscopy, RAMAN Spectroscopy, FTIR Spectroscopy
Manufacturer
Shimadzu
Industries
Materials Testing

GC/MS Analysis of Fluorophosphates as Decomposition Products in Lithium Battery Electrolyte

Applications
| 2024 | Shimadzu
Instrumentation
GC/MSD, GC/SQ
Manufacturer
Shimadzu
Industries
Energy & Chemicals
 

Related articles

Pavel Plevka: I only give my team colleagues projects that I would be happy to work on myself
Article | Scientists

Pavel Plevka: I only give my team colleagues projects that I would be happy to work on myself

Virologist Pavel Plevka, two-time ERC grant holder at CEITEC MU, seeks new team members. He discusses virus research, team leadership, and opportunities for students and postdocs.
CEITEC
tag
share
more
A Winning Lab
Article | Science and research

A Winning Lab

A Winning Lab - Chemistry professor receives new lab equipment that expands research capacity and student training.
William & Mary
tag
share
more
News from LabRulezGCMS Library - Week 7, 2025
Article | Application

News from LabRulezGCMS Library - Week 7, 2025

This week we bring you application and technical notes by Agilent Technologies, Thermo Fisher Scientific and Shimadzu!
LabRulez
tag
share
more
Natural Gas Analyser B - Quick Reference Guide
Article | Product

Natural Gas Analyser B - Quick Reference Guide

The NGA (System B) is a standard turnkey system designed for analysing natural gas and de-methaniser hydrocarbon matrices.
ChromSolutions
tag
share
more
Other projects
LCMS
ICPMS
Follow us
More information
WebinarsAbout usContact usTerms of use
LabRulez s.r.o. All rights reserved. Content available under a CC BY-SA 4.0 Attribution-ShareAlike