Join us for a free two-day LECO Separation Science Workshop on September 23–24, 2026, at the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/219">C³AL Laboratory</a> at Cal State LA. Registration is free, and meals and refreshments will be provided throughout the workshop.&nbsp;<h4>Registration</h4><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://forms.cloud.microsoft/pages/responsepage.aspx?id=iYeNbqIuykW7qZP4_jUEVbznDB40eK1PgjPzhHyb__9URTFTTFA5UEEzQ1A4MUtFV0o4TEJTNlZCOS4u&amp;route=shorturl">Register HERE</a>Space is limited, register today!<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg" alt="LECO: LECO Separation Science Workshop - QR code for registration" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg 156w," sizes="100vw" width="437" height="437"></blockquote><h4>Hand-on Experience with the LECO Complex Chemical Composition Analysis Lab C3AL</h4><ul><li>Work directly with LECO instruments in the C3AL Laboratory</li><li>Learn complete analytical workflows from sample to answer</li><li>Get expert guidance from LECO application scientists</li><li>Develop methods and solve real-world challenges</li><li>Collaborate, ask questions, and build your skills</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg" alt="Cal State LA: The LECO Pegasus BTX system in Cal State LA’s LECO Complex Chemical Compositional Analysis Lab enhances research and student training in advanced chemical analysis" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg 227w," sizes="100vw" width="1252" height="863">The first day will focus on the fundamentals and theory of comprehensive two-dimensional gas chromatography (GC×GC), with an emphasis on understanding how GC×GC can enhance your research, solve complex analytical challenges, and support your laboratory or company goals.&nbsp;The second day will be dedicated to hands-on activities, giving participants the opportunity to work directly with LECO instrumentation, learn practical analytical workflows, and analyze their own samples with guidance from LECO application scientists.&nbsp;Whether you are new to GC×GC or looking to expand its use in your research or organization, this workshop offers a unique opportunity to learn, explore, and apply the technology in a practical setting. Space is limited, so register early!<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg" alt="Cal State LA: LECO QUADJET GCxGC coupled to Pegasus BT 4D TOM MS in the Complex Chemical Composition Analysis Lab (C³AL)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/thumbnail_Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg 234w," sizes="100vw" width="1949" height="1299">

LECO Separation Science Workshop

This study presents a robust GC-MS method for direct detection and quantification of hydrogen in complex gas mixtures using electron ionization without dopants, reagent gases, or ion–molecule reactions. A modified EI source combined with a cryogenically cooled single capillary column achieved baseline separation of hydrogen from permanent gases and hydrocarbons in refinery gas while using helium as the carrier gas.The method demonstrated high sensitivity, linearity, and reproducibility across trace- and percent-level hydrogen concentrations. By simultaneously profiling other gas components in a single run, the approach simplifies conventional multi-column workflows and extends GC-MS capabilities for hydrogen analysis in complex industrial gas mixtures.<blockquote><h4>The original article</h4><h4><a target="_blank" rel="noopener noreferrer" href="https://pubs.acs.org/ancham/article/98/26/19493/5200102/Hydrogen-Analysis-by-Gas-Chromatography-Mass#247324328">Hydrogen Analysis by Gas Chromatography–Mass Spectrometry&nbsp;</a></h4>Vladislav V. Lobodin* ; Yensil Park; Charles E. A. FinneyAnal. Chem. (2026) 98 (26): 19493–19499.<div><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021/acs.analchem.6c00257">https://doi.org/10.1021/acs.analchem.6c00257</a></div><h6>licensed under <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a></h6></blockquote>Selected sections from the article follow. Formats and hyperlinks were adapted from the original.<div><div><div><div>Hydrogen analysis in complex gas mixtures, including permanent gases, and volatile and semivolatile organic and inorganic compounds, is crucial for optimizing hydrogen production, storage and use, and ensuring reliability across diverse applications. Accurate hydrogen analysis underpins production and distribution processes such as steam methane reforming, gasification, and electrolysis, helping maintain purity and quality throughout the supply chain. (<a href="javascript:;">1</a>) Reliable hydrogen measurements are also critical for fuel cell power generation, where automotive manufacturers and fueling stations must meet strict fuel quality standards to ensure safety and performance. (<a href="javascript:;">2, 3</a>) Hydrogen is a flammable, colorless, and odorless gas that poses significant hazards in air at levels between 4 and 74%. (<a href="javascript:;">4, 5</a>)</div><div>Many industrial processes, including chemicals and petrochemicals, steel manufacturing, glass production, and electronics, depend on precise hydrogen measurements for process control, quality assurance, and energy efficiency. (<a href="javascript:;">6−9</a>) Beyond these established uses, hydrogen analysis plays a vital role in energy storage, power generation, and utilization as a fuel for transportation and grid applications (e.g., power-to-gas and sustainable integration), with monitoring required to maintain the integrity and safety of stored and injected hydrogen. (<a href="javascript:;">10, 11</a>) It is also essential for environmental monitoring, including leak detection, emissions control, (<a href="javascript:;">5, 12</a>) and geological exploration of natural hydrogen sources. (<a href="javascript:;">13−15</a>) In the aerospace industry, hydrogen analysis ensures its safe handling and optimal performance of hydrogen as a fuel or propellant. (<a href="javascript:;">16−18</a>) In addition, forensic studies also rely on hydrogen measurements to provide critical evidence in criminal investigations and legal cases. (<a href="javascript:;">19, 20</a>)</div><div>A GC coupled to thermal conductivity detector (TCD) continues to be a common method of choice for hydrogen analysis despite the detector limitations. (<a href="javascript:;">21, 22</a>) However, the use of helium as a carrier gas, despite being the most popular choice, results in complications with a TCD because the thermal conductivity for hydrogen and helium is very close and hydrogen produces a relatively low and nonlinear response. To avoid the hydrogen–helium interference, argon or nitrogen is used as the carrier gas with a TCD. However, the use of those gases compromises chromatographic resolution, significantly reduces sensitivity for the other compounds by a factor of ∼10, and can interfere with the detection of other analytes.</div><div>Besides a TCD, a helium ionization detector (HID) and an atomic emission detector (AED) are utilized by coupling to a GC to analyze hydrogen. (<a href="javascript:;">23, 24</a>) As in the case of a TCD, these detectors suffer from limitations and more importantly are not informative enough for identification of unknown chromatographic peaks during the hydrogen production development. Raman spectroscopy can detect low hydrogen concentrations but suffers from low sensitivity, complex setups, and long measurement times. Commercial systems have high detection limits and reduced precision over time, limiting practicality for dynamic or in-line applications. (<a href="javascript:;">25, 26</a>)</div><div>In contrast, GC coupled to MS serves as a powerful tool for both qualitative and quantitative analysis of various compound mixtures. (<a href="javascript:;">27</a>) Nonetheless, it has been reported that GC–MS faces challenges due to the difficulties of detecting lighter gases relative to the carrier gas (<a href="javascript:;">28, 29</a>) and direct EI in the absence of a dopant and ion–molecule reactions has been considered an impossible task. (<a href="javascript:;">29</a>)</div><div>Chromatographic analysis of hydrogen typically involved a dual-column setup to effectively separate it from other gases like O2, N2, CO, CO2, CH4, and various volatile hydrocarbons. These setups often used packed columns or molecular sieves PLOT columns, which additionally necessitated a particle trap on the detector side to block sorbent particles from entering the mass spectrometer’s ion source. (<a href="javascript:;">30, 31</a>)</div><div>In the present study, we report the development of a novel method for hydrogen analysis that employs direct EI of hydrogen and a simplified column configuration with a single capillary column. This approach is capable of detecting hydrogen across a broad concentration range, including trace levels in complex matrices. Importantly, our method also delivers compositional information for other gases in a single run, which can provide valuable context for many applications, thereby providing a significant advancement in hydrogen analysis methodology.<h4>Experimental Part</h4>The development of the method for hydrogen analysis was conducted with a GC–MS instrument employing an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7890B">Agilent 7890B GC</a> system and an Agilent <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=5977B">5977B mass spectrometer</a> (Agilent Technologies, Santa Clara, CA). The GC system was modified with a liquid N2 cryogenic valve kit (Agilent G3466A) to enable operation at low temperatures and liquid N2 (supplied from a Dewar) was used to cool the GC oven. Chromatography-grade helium with a purity of 99.9999% from Airgas (Radnor, PA) additionally passed through a helium purifier trap (model RMSH-2) from Agilent Technologies at a flow rate of 2.0 mL·min–1 was used as a carrier gas. The gas chromatograph inlet temperature was set to 200 °C. The GC oven temperature was programmed to hold at −80 °C for 2 min, subsequently ramped to 260 °C at 20 °C·min–1, and then held for 17 min. The transfer line was kept at 260 °C. A GS-GASPRO GC column (60 m long, 320 μm ID) from Agilent Technologies was used for chromatographic separation. The ion source was held at 230 °C. The EI ion source was modified by replacing a standard (350 G) magnet with a low-gauss magnet (220 G) assembly (Agilent part: G3163-60560). The hydrogen tune macros were procured from Diablo Analytical (Antioch, CA) and are described elsewhere. (<a href="javascript:;">32</a>) Both selected ion monitoring (SIM) and scan modes (recorded as a total ion chromatogram [TIC]) were utilized for detection of hydrogen and other gases. In particular, hydrogen detection was performed using SIM mode at a mass-to-charge ratio (m/z) of 2.<h4>Results and Discussion</h4><div>Here, we describe the development of a new hydrogen analysis approach that utilizes direct EI and selective detection at m/z = 2. Because the conventional EI source magnetic field is optimized to confine and focus electrons for ionization of species with m/z ≥ 10, this configuration is suboptimal for hydrogen, resulting in limited ionization efficiency and inefficient extraction of low-mass ions. The modification of the EI ion source with a low-gauss magnet is necessary to improve the formation and detection of H2+ ions. Reduction of the magnetic field strength decreases confinement of ionizing electrons emitted by the filament, thereby increasing the effective interaction volume and residence time of electrons with hydrogen molecules and enhancing ionization probability. In addition, the reduced magnetic field mitigates discrimination against low-mass ions during extraction and transmission into the mass analyzer. Collectively, these effects enhance sensitivity for H2 detection under EI conditions, eliminating the need for chemical ionization or indirect detection strategies.</div><div>In addition to the specialized hardware, custom low-mass optimization tune macros are required to achieve reliable sensitivity. We used tune macros from a hydrogen detection kit developed for Agilent MSD instruments that had been converted into standalone RGA-type mass analyzers. (<a href="javascript:;">32</a>) The tuning and mass-calibration procedure began with a low-mass autotune (lomass.u), followed by a helium optimization tune that used the helium carrier gas flowing through the column into the ion source as the tuning mixture. The optimization tune adjusts key ion–optics parameters, including repeller voltage, ion focus, electron energy, emission current, and entrance lens offset to maximize the response at m/z = 4. Additionally, ions at m/z = 69, 131, and 219 from the instrument’s calibration compound (PFTBA) were used to calibrate the mass axis, adjust the electron multiplier voltage, and set appropriate peak widths.<div>The mass spectrometry detection method involved simultaneous acquisition in SIM mode at m/z = 2 for hydrogen detection, and scan mode (at 2.4 scans s–1) within the range of m/z = 10–160 for other gases. Attempts to scan from m/z = 1.6 to 160 and subsequently extract the ion chromatogram at m/z = 2 resulted in a significantly lower signal response for hydrogen detection. Detection of hydrogen in SIM mode at m/z = 2 significantly improves the signal-to-noise (S/N) ratio and detection limit. The dwell time (the time during which the quadrupole is set at m/z = 2) was adjusted to 100 ms to enhance sensitivity. The high-resolution quadrupole settings (with peak width of 0.5 m/z) further improved S/N ratio by a factor of 2.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Anal_Chem_2026_98_26_19493_19499_Figure_1_GC_MS_analysis_of_hydrogen_standard_gas_mixtures_9439c835f2.jpg" alt="Anal. Chem. (2026) 98 (26): 19493–19499: Figure 1. GC–MS analysis of hydrogen standard gas mixtures. Upper figures show scans from m/z = 10–160, and lower figures show detection at m/z = 2. Left: 5% (50000 ppm) H2. Right: 5000 ppm of H2. Nitrogen is a balance gas." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Anal_Chem_2026_98_26_19493_19499_Figure_1_GC_MS_analysis_of_hydrogen_standard_gas_mixtures_9439c835f2.jpg 245w," sizes="100vw" width="1600" height="1022"></div><div>Standalone mass spectrometers (without GC) are often employed as RGAs, including for hydrogen detection. However, the absence of chromatographic separation limits reliable hydrogen quantification and comprehensive characterization of other species in a mixture. Furthermore, quadrupole mass spectrometers, commonly used both as RGAs and in GC–MS configurations, are subject to the “zero-blast” effect. (<a href="javascript:;">35</a>) This occurs when low DC voltage and RF amplitudes at low m/z are insufficient to prevent heavier ions from reaching the detector, leading to false signals in the low m/z range up to m/z = 4, even in the absence of corresponding low molecular weight analytes such as H2 or He. (<a href="javascript:;">36</a>) The “zero-blast” effect is particularly noticeable when measuring low levels of hydrogen amidst significantly higher concentrations of heavier gases, e.g., N2, O2, CO, Ar, CO2, H2O, hydrocarbons. This interference, which fluctuates constantly, makes the detection and resolution of hydrogen peaks at m/z = 2 highly challenging. <a href="javascript:;">Figure 1</a> shows the GC–MS analysis of two standard gas mixtures containing 50000 and 5000 ppm hydrogen with nitrogen as the balance gas. The injected sample volume was 250 μL, and the split ratio was 20:1. The upper plots display total ion chromatograms for the mass range m/z = 10–160, where the peak at 4.1 min corresponds to N2. The lower plots show extracted ion chromatograms at m/z = 2, where the peak at 3.4 min represents H2, while the peak at 4.1 min, matching the nitrogen elution time, is a false signal caused by the “zero-blast” effect. This interference is especially pronounced at lower hydrogen concentrations and would significantly affect quantitation in the absence of chromatographic resolution. By separating hydrogen into a distinct chromatographic peak with GC–MS, the “zero-blast” interference can be minimized. Therefore, efficient chromatographic separation of hydrogen from other gases is essential for reliable detection and quantification.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Anal_Chem_2026_98_26_19493_19499_Figure_4_GC_MS_analysis_of_refinery_gas_mixture_2977041c4b.jpg" alt="Anal. Chem. (2026) 98 (26): 19493–19499: Figure 4. GC–MS analysis of refinery gas mixture. Top. TIC for m/z = 10–160. Bottom. SIM at m/z = 2." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Anal_Chem_2026_98_26_19493_19499_Figure_4_GC_MS_analysis_of_refinery_gas_mixture_2977041c4b.jpg 226w," sizes="100vw" width="1600" height="1104"><a href="javascript:;">Figure 4</a> presents the gas chromatographic separation and mass spectrometric detection of a refinery gas test mixture using a combined scan (m/z = 10–160) and SIM (m/z = 2) acquisition mode. The total ion chromatogram (top panel) demonstrates excellent baseline separation of all major permanent gases and hydrocarbons, including O2, N2, CO, CH4, CO2, C2H4, C2H6, propane, propylene, n-butane, iso-butane, and various C5 isomers. Notably, even isobaric species such as N2, CO, and C2H4, each with nominal mass of 28 Da, are fully resolved chromatographically, enabling accurate identification and quantitation despite their identical molecular weights.The SIM trace at m/z = 2 (bottom panel) highlights the selective detection of hydrogen. One of the most critical regions for hydrogen separation is between 2 and 7 min, where H2 elutes well before O2, N2, CO, and CH4. This complete chromatographic resolution effectively eliminates interference from the quadrupole “zero-blast” effect and suppresses false low-mass signals that typically arise from high concentrations of heavier gases, thereby ensuring reliable and interference-free quantitation of hydrogen. The combination of efficient separation and SIM-based detection provides a robust analytical platform for accurate measurement of hydrogen in complex gas mixtures.</div></div><h4>Conclusions</h4>We successfully developed and validated a robust GC–MS method capable of directly detecting and quantifying hydrogen using EI without the need for dopants, reagent gases, or ion–molecule reaction schemes traditionally required for low-mass. By integrating specialized low-mass tuning procedures, a modified EI source, and a cryogenically cooled single-capillary column, we achieved efficient baseline chromatographic separation of hydrogen from other permanent gases, hydrocarbons, and isobaric species in complex gas mixtures. This separation was essential to eliminate false low-mass signals originating from the quadrupole “zero-blast” effect, and provided accurate, interference-free hydrogen quantitation. The method demonstrated high sensitivity and selectivity across more than 3 orders of magnitude concentration ranges from 5 to 5000 ppm, with excellent linearity (R2 = 0.9999). The combination of adjustable sample-loop volumes and tunable split ratios allowed optimization of peak shape and signal-to-noise performance for both trace-level and percent-level hydrogen concentrations. Triplicate analyses showed exceptional reproducibility, with variability below 1%, confirming suitability of the sampling approach for reliable quantitative analysis. Importantly, this approach provides simultaneous compositional information for a wide range of gases in a single analytical run, enabling comprehensive characterization of complex mixtures. This capability is particularly valuable for hydrogen production, storage, fuel-quality monitoring, geologic hydrogen exploration, industrial process control, safety and forensic applications, and environmental assessments where hydrogen must be measured alongside a panel of other gases.</div></div></div></div>

Hydrogen Analysis by Gas Chromatography–Mass Spectrometry

In the week of August 24, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars">👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</a></h4>👉 Search and filter in the largest global database with over 5 500 GC, LC, MS and spectroscopy webinars.</blockquote><h5>1. Thermo Fisher Scientific: From legacy to leading edge: unlock more uptime, throughput, and confidence with modern GC-MS technology</h5><ul><li>Tu, 25.8.2026 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/6457">Registration</a></li></ul>Discover how upgrading legacy GC-MS systems to the Thermo Scientific ISQ 7610 GC-MS and TSQ 9610 GC-MS/MS can improve performance, simplify maintenance, and reduce operating costs.<h5>2. Waters Corporation: Foundations of a Sustainable, High-Performing QA Program</h5><ul><li>We, 26.8.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/6448">Registration</a></li></ul>Build a sustainable, high-performing QA program in your lab. Learn the four pillars of data quality: method validation, analyst competency, control charting, and certified reference materials.

Webinars LabRulezGCMS Week 35/2026

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In 1936, the Laboratory Equipment Company introduced the first rapid carbon determinator for the American iron and steel industry.  Today, almost 80 years later, LECO is recognized globally as a leader in the development of high-quality analytical instrumentation, mass spectrometers, comprehensive two-dimensional chromatography, metallography & optical equipment as well as consumables.

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Agilent Technologies

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This presentation will cover products from Agilent that make GC connections more robust by utilizing new technologies that make connections easier, leak free and more inert for any application.Topics covered include: Self Tightening Stainless Column Nuts and ferrules, Press Fits, UltiMetal Plus and Stainless Steel Capillary Tubing, Ferrule Pre-swaging installation tool and MS interface installation tool, among others.<blockquote>Speaker: Mark Sinnott (Technical Support Engineer, Consumables and Supplies Division, Agilent Technologies)Mark Sinnott works for Agilent Technologies as a Technical Support Engineer in the Consumables and Supplies Division (CSD). In his position at Agilent, Mark performs technical support and applications assistance to gas chromatographers worldwide. He has more than 22 years of experience in gas chromatography, including environmental analysis of compounds in air, soil and water matrices, including dissolved gas analysis for the electrical industry. Mark holds a Master’s Degree in Chemistry from California State University, Sacramento, and currently resides in Twin Falls Idaho.</blockquote>

Agilent Technologies: Becoming A Better Chromatographer - GC Webinar Series

From Inlet to Detector: Building Better Connections in GC and GC/MS Workflows

Build better GC and GC/MS connections with Agilent. Explore self-tightening column nuts, pre-swaging tools, and inert capillaries to eliminate leaks

Building Better Connections in GC and GC/MS Workflows

<div><div id="inner_content_body_text" data-content-id="394785">Polymers are complex materials, and understanding their performance requires more than just mechanical testing. Rheology provides valuable information on viscosity, elasticity, and flow, but it cannot fully explain the chemical and structural changes that occur during processing. By integrating rheology with Raman spectroscopy, researchers and engineers can correlate mechanical behavior with molecular-level insights in real time.This combined Rheo-Raman approach opens up new possibilities for understanding polymerization, crystallization, and thermal stability, supporting better formulation, troubleshooting, and quality control across the polymer industry.<h4>Key Learning Topics:</h4><ul><li>How Rheo-Raman correlates mechanical properties with chemical structure to deliver deeper insights into polymer behavior</li><li>How to monitor polymerization reactions and chemical transformations in real time</li><li>How to study crystallization pathways and their impact on material performance</li><li>How to assess thermal stability and degradation during processing or use</li><li>How Rheo-Raman supports faster material development, improved quality control, and problem-solving in industrial and research settings</li></ul><blockquote>Presenter: James P. Eickhoff Jr.James Eickhoff is the principal application engineer for the rheology division as a member of the Advanced Technical Support Center at Anton Paar USA. He has over 20 years of theoretical and experimental rheology training, including the last 17 years with Anton Paar having guided current and prospective customers on the use of rheological techniques in their industrial and academic research. James earned a Bachelor’s and Master’s Degree in Chemical Engineering from Michigan Technological University and Clemson University, respectively.</blockquote></div></div>

Anton Paar: Correlating Mechanical and Chemical Properties: Introduction to Rheo-Raman for Polymers

Correlating Mechanical and Chemical Properties: Introduction to Rheo-Raman for Polymers

Learn how Rheo-Raman combines rheology and Raman spectroscopy to study polymerization, crystallization, and polymer performance in real time.

Introduction to Rheo-Raman for Polymers

Laboratories are under growing pressure to handle increasing volumes of samples and data while operating under tighter regulatory inspection, all without compromising turnaround times or traceability. In this context, many organizations attempt to extend existing workflows and legacy tools, which can introduce inefficiencies, increase manual effort, and create compliance risks. At the same time, it is not always clear which digital solutions are best suited to address these challenges.This presentation illustrates how modern digital laboratory environments streamline routine activities by minimizing manual tasks and embedding compliance directly into everyday workflows. Drawing on a real-world use case, we show how automated capture of data from multiple sample measurements at the point of execution enables a continuous, sample-centric workflow.By removing manual interventions and paper-based processes, laboratories can improve efficiency and visibility, support faster and more reliable decision-making while remaining responsive to evolving customer demands.<h4>Learning Points</h4><ul><li>The role of different systems (LIMS, SDMS, ELN) within the digital lab landscape and how they differ from each other's</li><li>How WebLab manages laboratory operations from a sample perspective, enabling you to track every sample, stage, and next action across workflows</li><li>How automated data capture from connected instruments helps reduce errors, lower contamination risks, and accelerate sample processing</li><li>You will see, through a real-life example, how integrated digital workflows improve data quality, accelerate reporting, and increase operational efficiency</li></ul><h4>Who should attend</h4>Professionals working in small to mid‑sized laboratories, including:<ul><li>Directors and Managers of Analytical, QC, or Contract Labs</li><li>Lab Operations and QA/QC Leaders</li><li>Digitalization and IT at organizations transitioning from paper, Excel, or legacy systems to LIMS</li></ul><blockquote>Presenter: Peter Bellstedt, PhD (Director of Business Development and Product Manager at SciY)Peter studied Biochemistry at the University of Jena before completing a PhD on the structural characterization of a DNA repair protein using solution and solid-state NMR. He was then appointed as the head of the NMR Spectroscopy Platform in Jena, Germany, where he pioneered the implementation of modern, highly efficient data-driven workflows. After five years, he moved to the University of Zurich, Switzerland, as a principal investigator, where his lab focused on structure-based drug discovery. This year, he brought his wealth of experience to the LOGS by SciY team, focusing on efficient workflow solutions for research labs and facilities on a global scale.</blockquote>

SciY: From Legacy Workflows to Paperless Labs: Track Every Sample, Process, and Decision

From Legacy Workflows to Paperless Labs: Track Every Sample, Process, and Decision

Transition from paper to a paperless lab. Discover how WebLab, LIMS, and automated data capture streamline sample tracking and boost compliance

Paperless Labs & Sample Tracking: Digital LIMS Workflows

The challenge of developing and maintaining robust chemometric models for use within Process Analytical Technology (PAT) deployment remains a significant barrier to implementation. This webinar explores how Iterative Optimization Technology (IOT) is advancing the principles of lean chemometrics by reducing the calibration burden associated with PAT deployment. Case studies will demonstrate how these methods enable faster model deployment, improved lifecycle management, and greater operational efficiency without compromising product quality or process understanding. Attendees will gain insights into how innovative chemometric strategies can accelerate PAT adoption while supporting the industry's drive towards agile, data-driven manufacturing.<h4>Learning Points</h4><ul><li>You will learn how lean chemometrics reduces model complexity and data requirements</li><li>Discover how to simplify model deployment and lifecycle management</li><li>Explore how to accelerate PAT adoption while maintaining process understanding and quality</li></ul><h4>Who should attend</h4><ul><li>Process development and MSAT teams scaling processes to manufacturing</li><li>PAT scientists and analytical experts developing chemometric models</li><li>Lab managers driving efficient and scalable PAT implementation</li><li>Development and manufacturing and digitalization leaders advancing data-driven operations</li></ul><blockquote>Presenter: Jonique Samuels (Scientific Advisor for Innovations, SciY)Jonique Samuels is a Scientific Advisor for Innovations at SciY where she leads research and development projects on new, novel functionality for synTQ, the orchestration and real-time process-control platform that enables PAT and advanced, quality-centric control strategies. Currently, Jonique's focus is on supporting sustainability initiatives with customers, which includes investigating and developing lean chemometrics methods.&nbsp;</blockquote><blockquote>Presenter: Anna Codina, Ph.D. ( Senior Director Strategy and Business Development, SciY)Anna Codina is Senior Director of Strategy and Business Development at SciY, where she focuses on enabling data-driven orchestration across the pharmaceutical value chain. With a background in experimental science, analytical development, and digital innovation, she works at the intersection of data, automation, and AI to accelerate scientific workflows and decision-making.Anna holds a Ph.D. in protein NMR from the University of Barcelona and completed postdoctoral research at the MRC Laboratory of Molecular Biology in Cambridge. She spent seven years in Analytical R&amp;D at Pfizer, specializing in reaction monitoring, impurity characterization, and regulatory submissions, and was recognized with a Pfizer Worldwide Achievement Award for implementing NMR-based reaction monitoring in an open-access environment.Since joining Bruker, Anna has held multiple leadership roles across applications, product management, and biopharma business development and market management. In her current role at SciY, she drives strategy for vendor-agnostic data platforms and digital solutions that connect instruments, robotics, and enterprise systems enabling orchestration, AI-powered experimentation and scalable workflows across R&amp;D, CROs/CDMOs, and manufacturing.</blockquote>

SciY: Advancing Lean Chemometrics: Iterative Optimization Technology as a Process Analytical Technology Tool for Reducing Calibration Burden

Advancing Lean Chemometrics: Iterative Optimization Technology as a Process Analytical Technology Tool for Reducing Calibration Burden

Reduce PAT calibration burden with Lean Chemometrics and IOT. Learn to accelerate model deployment and simplify lifecycle management in this webinar

Lean Chemometrics & IOT: Reducing PAT Calibration Burden

Simplifed, turnkey workflows of the Agilent 8700 LDIR.<blockquote>Presenter: Louis Tisinger, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)Louis (Lou) Tisinger has a Ph.D. in Analytical Chemistry from Miami University in Oxford Ohio, where his graduate research involved the study of ATR imaging and microscope performance in vibrational spectroscopy. Most of his career has been related to pre- and post-sales support of FTIR spectrometers, microscopes, imaging systems, and thermal analytical instruments, focusing on analyzing customer samples, demonstrations, post-sales training, troubleshooting, and R&amp;D.</blockquote>

Agilent Technologies: IR Microscopy to Streamline Your Microplastics Analysis

IR Microscopy to Streamline Your Microplastics Analysis

discover streamlined microplastics analysis using IR microscopy. Learn how the Agilent 8700 LDIR system provides automated workflows for fast testing

Agilent 8700 LDIR: Streamlined Microplastics Analysis

Contamination is one of the most common causes of deteriorated product quality and equipment performance in industrial environment. FTIR has been proven to be a valuable tool to characterize the contamination rapidly and economically. Agilent’s compact and portable FTIR spectrometers provide a complete product portfolio with versatile sampling interfaces and spectral process capabilities, which can offer great convenience, stability and high-throughput solution to the contamination-related applications.<blockquote>Presenter:&nbsp; Yanqia Wang, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)Dr. Yanqia Wang started working for Agilent Technologies Inc. as a FTIR application Engineer in 2013, providing pre-&amp;post-sale application support. The products he covers from Bench-top FTIR microscopes to various Mobile FTIR spectrometers. Dr. Wang received his PhD of analytical chemistry from Duke University in 2004, doing dynamic IR spectroscopy research. Then he joined Fitzpatrick Center for Photonics at Duke University, doing Tissue Raman spectrometer instrumentation. Since 2007, Dr. Wang worked for Avery Dennison Corp. as a spectroscopist, providing molecular analytical support to the research &amp; development.</blockquote>

Agilent Technologies: Learn How FTIR Can Help You with Contamination and Poor Product Quality

Learn How FTIR Can Help You with Contamination and Poor Product Quality

Solve contamination and quality issues with Agilent FTIR. Learn how compact, portable FTIR spectrometers enable fast, high-throughput identification

Agilent FTIR: Rapid Contamination Analysis

This session will focus on setting up a simple quantification method by FTIR, using MicroLab and MicroLab Quant. It will include scanning standards and showing how to use them in preparation of the calibration curve, through to the analysis of real samples by FTIR.<blockquote>Presenter:&nbsp; Louis Tisinger, PhD (Application Engineer, Molecular Spectroscopy, Agilent Technologies, Inc.)Louis (Lou) Tisinger has a Ph.D. in Analytical Chemistry from Miami University in Oxford Ohio, where his graduate research involved the study of ATR imaging and microscope performance in vibrational spectroscopy. Most of his career has been related to pre- and post-sales support of FTIR spectrometers, microscopes, imaging systems, and thermal analytical instruments, focusing on analyzing customer samples, demonstrations, post-sales training, troubleshooting, and R&amp;D.</blockquote>

Agilent Technologies: How to Perform Routine Quantification by FTIR: Tips & Tricks Workshop

How to Perform Routine Quantification by FTIR: Tips & Tricks Workshop

Master routine FTIR quantification. Learn how to use MicroLab and MicroLab Quant software to measure standards, build calibration curves, and test samples

Routine FTIR Quantification Workshop: MicroLab Tips

<h4>Build Confidence in Your Laboratory Data</h4>Reliable laboratory data doesn't happen by chance, it is the result of a quality assurance program designed to detect risk, drive consistency, and support continuous improvement.In this webinar, we'll explore the four foundational elements of an effective QA program: method development, analyst training, ongoing performance monitoring, and corrective action. Learn how laboratories can use precision, accuracy, control charting, trending analysis, and root cause investigations to identify issues before they impact data quality.We'll also discuss practical strategies for verifying method performance, demonstrating analyst competency, sustaining long-term process control, and using certified reference materials as independent tools to strengthen confidence in analytical results.Whether you are building a new QA program or looking to improve an existing one, this session provides actionable guidance for creating a robust and sustainable framework for quality.<h5>Key takeaways</h5><ul><li>Build a more effective and sustainable laboratory QA program.</li><li>Use precision, accuracy, and control charting to improve data quality and identify issues early.</li><li>Apply root cause analysis and certified reference materials to strengthen performance and corrective actions.</li></ul>Who should attendThis webinar is designed for Quality Assurance (QA) and Quality Control (QC) managers, analytical chemists and laboratory scientists, laboratory managers and supervisors.Don't miss it!<blockquote>Speaker:&nbsp;Christy Abbas, PhD (Sr. Product Marketing Manager, Waters ERA)Christy has been with Waters ERA for six and a half years. Her career spans roles at an instrument manufacturer, a biopharmaceutical laboratory, and a mining company. She earned her PhD in Applied Chemistry from the Colorado School of Mines.Throughout her career, Christy has supported the nuclear, pharmaceutical, and chemical industries, as well as academia. Drawing on her background in analytical chemistry, product development, marketing, and sales, she is focused on expanding Waters ERA’s product portfolio to better meet evolving customer needs.</blockquote>

Foundations of a Sustainable, High-Performing QA Program

Build a sustainable QA program for your laboratory. Learn how control charting, root cause analysis, and reference materials drive data confidence

Sustainable Laboratory QA: Control Charts & Data Integrity

<div>Rapid microbial analysis is essential for maintaining product quality, ensuring safety, and supporting efficient laboratory workflows, yet selecting the most appropriate analytical approach can be challenging.This educational webinar explores three complementary methods—matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for microbial identification, Fourier transform infrared (FTIR) spectroscopy for microbial strain typing, and automated DNA/RNA electrophoresis for genetic analysis.Through practical examples and application-focused discussion, attendees will gain a clearer understanding of each technique's strengths, limitations, and ideal use cases, helping them make more informed decisions when designing or optimizing microbial testing workflows.Attend this webinar to:<ul><li>Understand how MALDI-TOF MS, FTIR, and automated DNA/RNA electrophoresis address different microbial analysis challenges</li><li>Learn how these three methods can support faster and more efficient microbial testing workflows</li><li>Evaluate which analytical approach is best suited to specific microbial testing applications and laboratory objectives</li><li>Apply practical considerations when implementing microbial identification, bacterial classification, or genetic analysis techniques in routine testing</li></ul><blockquote>Presenter: Kaoru Nakagawa (Assistant Manager, Application Specialist (MALDI), Shimadzu Corporation)Kaoru Nakagawa joined Shimadzu Corporation in 2008. She began her career at the Koichi Tanaka Mass Spectrometry Research Laboratory, where she developed highly sensitive glycan analysis methods using MALDI-MS with liquid-matrix-based on-plate labeling. Kaoru later moved to a customer-facing role, supporting applications such as, MALDI-MS imaging technologies, including on-tissue chemical derivatization. Today, her work focuses on developing rapid, practical methods for microbial identification using MALDI. Guided by Shimadzu’s corporate philosophy, “Contributing to society through science and technology,” she is dedicated to advancing mass spectrometry technologies that help address real-world scientific challenges.</blockquote><blockquote>Presenter: Nozomi Maeshima (Assistant Manager, Application Specialist (Life Science), Shimadzu Corporation)Nozomi Maeshima is an applications scientist at Shimadzu, where she has been involved in LC-MS application development in the life sciences field and in genetic analysis applications. She also leads promotional and marketing activities and supports customer inquiries. During university, she studied chemical biology and investigated the mechanisms of enzymes involved in biosynthetic processes. Nozomi brings a combination of research experience and applications expertise to help laboratories identify practical solutions for their analytical needs.</blockquote><blockquote>Presenter: Xu Yan ( Assistant Manager, Application Specialist (FTIR), Shimadzu Corporation)Xu Yan is an application chemist at Shimadzu Corporation with five years of experience developing FTIR applications for microbiology, environmental analysis, and GX-related fields. His work focuses on advancing practical FTIR applications and has gained extensive experience in method development and real-world implementation. In this session, Xu will present insights into the use of FTIR for microbiological analysis, including strain typing and related applications.</blockquote></div>

Technology Networks: Modern Methods for Faster Microbial Analysis

Modern Methods for Faster Microbial Analysis

Explore modern microbial analysis methods. Learn how MALDI-TOF MS, FTIR, and automated electrophoresis streamline identification, strain typing, and genetics

Modern Microbial Analysis: MALDI-TOF, FTIR & Electrophoresis

Legacy GC-MS systems can create costly bottlenecks through increased maintenance, reduced productivity, and limited analytical capabilities. Join our webinar to discover how upgrading from legacy GC-MS platforms to the latest Thermo Scientific™ ISQ™ 7610 Single Quadrupole GC-MS and TSQ™ 9610 Triple Quadrupole GC-MS/MS systems are helping laboratories modernize their workflows, achieve higher performance and stay ahead of evolving analytical demands.Learn how innovative technologies such as NeverVent maintenance, extended dynamic range, intelligent software tools, and advanced quantitative performance can help you generate trusted results faster while lowering operational costs. We will also discuss available upgrade incentives designed to support laboratories ready to replace aging GC-MS instrumentation.Whether you currently operate an older Thermo Scientific system or another legacy GC-MS platform, this webinar will provide practical insights into the benefits of modernization and explain how our limited-time upgrade promotion can help make the transition easier.<blockquote>Presenter: Amit Gujar (Product Manager GC-MS, Thermo Fisher Scientific)Amit Gujar, Ph.D. is a Product Manager with the GC, GC-MS business unit at Thermo Fisher Scientific. He has worked at Thermo for over 12 years and has been intimately involved with planning, development and commercial release of their most recent TRACE 1610, ISQ 7610 and TSQ 9610 GC and GC-MS systems. He has a Ph.D. in Chemical Engineering from University of Tulsa. He did a couple of stints as a postdoctoral scholar before coming to Thermo. The focus of his research has been catalysis, biofuels and clean energy.Moderator: Daniela Cavagnino (Product Marketing Manager, Thermo Fisher Scientific)</blockquote>

Thermo Fisher Scientific: From legacy to leading edge: unlock more uptime, throughput, and confidence with modern GC-MS technology

From legacy to leading edge: unlock more uptime, throughput, and confidence with modern GC-MS technology

Learn how modern Thermo Scientific GC-MS systems improve productivity, maintenance, quantitation, and workflow efficiency when replacing legacy instrumentation.

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