<div><p><strong>Per- and polyfluoroalkyl substances (PFAS) represent a vast class of more than 3,000 synthetic compounds containing perfluorinated chains (with the general formula CnF₂n+₁COOH), commonly utilized in a wide range of consumer products and industrial processes.</strong></p><p>The unique structure of PFAS, characterized by multiple carbon-fluorine (C-F) bonds, contributes to their <strong>exceptional chemical stability and resistance</strong> to degradation through environmental or biological processes. This durability makes them some of the <strong>most persistent pollutants in the environment</strong>. Their resistance to water and oil has led to widespread use in diverse applications, including water- and stain-repellent coatings for textiles, paints, personal care items, firefighting foams, fluoropolymer-based lubricants and additives, as well as grease- and water-resistant food packaging. Due to their extensive use, PFAS have been found in various environmental and biological samples, such as <strong>food, drinking water, wastewater, and human blood</strong>.</p></div><div><div><div><div><h3><strong>Why PFAS Testing Is Crucial?</strong></h3></div></div></div></div><div><p>Like many other chemicals, PFAS can cause<strong> </strong>various <strong>harmful health effects</strong>, depending on factors such as the level, duration, and route of exposure, as well as individual characteristics like age, sex, ethnicity, overall health, and genetic background. PFAS exposure has been linked to various health effects in both sexes, with some impacts supported by high certainty evidence—such as <strong>thyroid disease, liver damage, kidney cancer, and testicular cancer</strong>.</p><p>In females, PFAS may also affect pregnancy outcomes and fetal development, including increased miscarriage risk, reduced birth weight, and delayed mammary gland development. Because of their toxic nature, these compounds have been classified as “persistent organic pollutants” by the<strong> Stockholm Convention</strong> (including PFOS, PFOA, PFHxS, and their salts) and by the <strong>European Commission</strong> (including PFOA, PFOS, PFNA, and PFHxA). Their durability, chemical stability, harmful effects, and tendency to build up in living organisms make them a serious risk to both environmental and human health; hence, PFAS testing is crucial for monitoring and mitigating these threats.</p></div><div><div><div><div><h3><strong>PFAS Testing Techniques</strong></h3></div></div></div></div><div><p>PFAS testing employs advanced techniques to detect, identify, and quantify both known and emerging compounds across diverse environmental matrices.</p><h5><strong>Liquid Chromatography-Mass Spectrometry (LC-MS/MS)</strong></h5><p>LC-MS is a <strong>commonly used PFAS testing method</strong>. Samples are first processed using suitable preparation techniques, such as <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=136&amp;manufacturerItems=50"><strong>solid phase extraction </strong></a>(SPE). The resulting extracted samples are then examined using LC/MS/MS with calibration performed via standards. Target analytes are identified with help of isotopically labeled surrogate standards. . Additionally, product ion ratios are compared with those from standards to support identification. Once confirmed, the concentration of each identified target compound is determined based on the response of its main product ion using external standard calibration.</p></div><div><div><div><div><h4><strong>Gas Chromatography-Mass Spectrometry (GC-MS)</strong></h4></div></div></div></div><div><p>Non targeted analysis of PFAS has largely been dominated by LC-MS methods, although GC-MS can access a complementary chemical space, especially for volatile and semivolatile PFAS. Studies show that LC‑MS covers most ionic PFAS; GC‑MS captures neutral/volatile precursors less amenable to LC, highlighting the need for GC-based approaches. GC is particularly valuable for identifying novel PFAS and transformation products from sources like manufacturing waste, incineration, wastewater, and consumer products.</p></div><div><div><div><div><h4><strong>Total Organic Fluorine (TOF)</strong></h4></div></div></div></div><div><p>Total Organic Fluorine (TOF) analysis is an indirect method used to estimate the overall burden of per- and polyfluoroalkyl substances (PFAS) and other organofluorine compounds in a sample. Instead of targeting individual PFAS molecules, TOF methods quantify the sum of organically bound fluorine.</p><p>Because this process measures the organic fluorine present within a sample, it provides a helpful bulk measurement of fluorine from all PFAS present, including those which may not be covered by targeted LC-MS/MS methods.</p></div><div><div><div><div><h4><strong>High Resolution Mass Spectrometry (HRMS)</strong></h4></div></div></div></div><div><p>HRMS is increasingly used to detect emerging PFAS, with two main strategies applied for identification: suspect screening (SS) and non-target screening (NTS). SS is a more direct method, particularly effective when tandem mass spectrometry (MS/MS) reference spectra are available. In contrast, NTS is critical for uncovering new PFAS compounds in the absence of a suspect list, using fragment-based or homologue-based techniques.</p><p>HRMS contributes significantly by offering precise mass measurements, which are essential for identifying unknown substances. Since PFAS often form homologous series, patterns in accurate mass, retention time, and common fragments (such as CF₂, C₂F₄, and CF₂O) help in their recognition.</p></div><div><div><div><div><h3><strong>Choosing the Right Testing Method</strong></h3></div></div></div></div><div><p>C-MS/MS is the primary technique used for targeted PFAS analysis due to its high sensitivity and accuracy. It is validated by the U.S. EPA through established methods such as 1633, 533, and 537.1 for detecting PFAS in various environmental and drinking water samples. For laboratories seeking reliable and compliant workflows, choosing a comprehensive <a target="_blank" rel="noopener noreferrer" href="https://www.phenomenex.com/industries/pfas">P<strong>FAS analysis solution</strong></a> that aligns with these regulatory methods is essential for accurate detection and quantification.</p><ul><li><strong>EPA Method 1633</strong> is designed for use under the Clean Water Act (CWA) to measure the levels of 40 different PFAS in various sample types including water, soil, biosolids, sediment, and biological tissue, using <strong>LC-MS/MS</strong>. Weak anion exchange solid phase extraction (WAX-SPE) is employed for extracting various sample matrix types, and PFAS compounds are quantified through calibration with isotopically labeled internal standards.<br>&nbsp;</li><li><strong>EPA Method 533</strong> utilizes weak anion exchange solid phase extraction (WAX-SPE) followed by LC-MS/MS to detect 25 specific PFAS in drinking water, including short chain PFAs. This method employs tandem mass spectrometry and isotope dilution to improve analytical selectivity.<br>&nbsp;</li><li><strong>Method 537.1 </strong>involves extraction via SDBL reversed phase SPE combined with LC-MS/MS for detection of 18 specific PFAs compounds, including the novel GenX compound. This method involves <a target="_blank" rel="noopener noreferrer" href="https://www.phenomenex.com/documents/pfas-in-drinking-water">PFAS detection in drinking water</a> samples.</li></ul></div>

Guide to PFAS Testing Methods

ISC 2026 Program

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 15th June 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you brochure by <strong>Agilent Technologies, </strong>application note<strong> </strong>by<strong> Shimadzu</strong>, presentation by <strong>MDCW / Institut d’Investigació Sanitària Pere Virgili </strong>and poster by<strong> Waters Corporation!</strong></p><h3><strong>1. Agilent Technologies: </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8860B"><strong>Agilent 8860B Gas Chromatograph</strong></a></h3><ul><li>Brochure</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/ds_8860_gas_chromatograph_5994_9066en_agilent_f4d445178f.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8860B"><strong>Agilent 8860B gas chromatograph</strong></a> delivers reliable, repeatable performance for routine analyses, combining proven GC expertise with simplified operation. A bright color touchscreen provides quick access to system setpoints, configuration details, flowpath information, and live signal plots to easily monitor run progress. For deeper control, the built‑in Agilent GC Assist interface—optimized for tablets, PCs, and mobile devices—offers advanced system intelligence, including remote status checks, self‑guided diagnostics, maintenance tools, and method and sequence&nbsp;editing. The 8860B supports full electronic pneumatics control (EPC) or electronic pneumatics regulation (EPR), enabling precise, automated or electronically adjusted gas management. Both EPC and EPR use robust 7th‑generation microchannel architecture, designed for superior protection against contaminants and improved long-term reliability.</p><h4><strong>GC system capabilities&nbsp;</strong></h4><ul><li><strong>Retention time repeatability: </strong>&lt; 0.03% or 0.003 minutes&nbsp;</li><li><strong>Area repeatability:&nbsp;</strong><ul><li>&lt; 1.0% RSD&nbsp;</li><li>The 8860B display comes with physical start/stop buttons for manual analysis&nbsp;</li><li>Easy access to maintenance and service modes from the GC&nbsp;Assist interface, including autonomous leak checks&nbsp;</li><li>The GC Assist interface provides remote connectivity enabling you to monitor your smart GC system, check system logs, and perform diagnostics tests, from inside or outside the laboratory&nbsp;</li><li>Atmospheric pressure and temperature compensation are built into every system, so results do not change, even when the laboratory environment does.</li></ul></li><li><strong>Simultaneously supports&nbsp;</strong><ul><li>Two inlets&nbsp;</li><li>Three detectors &nbsp;</li><li>Support for up to any combination of three valves total:&nbsp;<ul><li>Up to four heated gas sample valves&nbsp;</li><li>Up to two liquid sampling valves&nbsp;</li></ul></li><li>Dual sample introduction capabilities:&nbsp;<ul><li>Supports two <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=7693A"><strong>7693A</strong></a> autoinjectors with capacity for 16&nbsp;sample vials&nbsp;</li><li>Supports one 7693A autoinjector and automatic sampler tray with capacity for 150 sample vials&nbsp;</li><li>Supports one 7650A autoinjector with capacity for 50 sample vials with one 7693A with capacity for 16&nbsp;sample vials&nbsp;</li><li>Supports one <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=PAL3"><strong>PAL3</strong></a> autosampler&nbsp;</li></ul></li></ul></li><li><strong>Instrument dimensions&nbsp;</strong><ul><li><strong>Height:</strong> 49 cm (19.2 in)&nbsp;</li><li><strong>Width:</strong> 58 cm (22.9 in), 68 cm with side-mounted detector&nbsp;</li><li><strong>Depth</strong>: 54 cm (21.3 in)&nbsp;</li><li><strong>Typical weight</strong>: 51 kg (112 lb)</li></ul></li></ul><h3><strong>2. MDCW / Institut d’Investigació Sanitària Pere Virgili: GcDUO: A Batch Processing Framework Integrating PARAFAC and PARAFAC2 for GC×GC-MS Data Analysis</strong></h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_10_Llambrich_54914668f8.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>The presentation introduces <strong>GcDUO</strong>, an open-source batch-processing framework developed for the analysis of comprehensive two-dimensional gas chromatography–mass spectrometry (GC×GC-MS) data. The tool was designed to address one of the main challenges in GC×GC-MS workflows: extracting meaningful chemical information from highly complex multidimensional datasets while reducing dependence on proprietary software. GcDUO combines the strengths of <strong>PARAFAC</strong> and <strong>PARAFAC2</strong> chemometric algorithms to perform automated peak detection, deconvolution, compound annotation, and quantification across large batches of samples.</p><p>The workflow begins with raw GC×GC-MS data imported from CDF files and converted into a four-dimensional matrix. Regions of interest (ROIs) are automatically selected using a watershed algorithm, allowing relevant chromatographic features to be isolated from the background. PARAFAC decomposition is then applied to separate overlapping compounds into their individual first-dimension retention times, second-dimension retention times, and mass spectra. Compound identification is performed using spectral similarity calculations, retention index information, and comparison against reference libraries, creating a consensus-based annotation strategy that improves confidence in identifications.</p><p>To further improve quantitative performance, GcDUO incorporates a constrained PARAFAC2 approach that can model chromatographic peak shifts between samples while preserving accurate peak integration. The framework was evaluated using benchmark GC×GC datasets containing fragrances, allergens, food-related compounds, and breath-analysis samples. Validation studies showed strong detection and annotation performance, including successful identification of most compounds in independent datasets such as FruityBeer and BreathMix. Quantitative comparisons with the widely used <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/41"><strong>ChromaTOF software</strong></a> demonstrated highly comparable retention times and peak areas for a range of volatile compounds, indicating that GcDUO can deliver results similar to established commercial platforms.</p><p>The authors conclude that GcDUO provides a powerful open-source alternative for GC×GC-MS data processing. The framework supports automated deconvolution, annotation, and quantification without requiring strict trilinearity assumptions often associated with traditional chemometric approaches. Although computational cost and user expertise remain important considerations, GcDUO offers performance comparable to gold-standard commercial software while expanding access to advanced GC×GC-MS data analysis for metabolomics, environmental, food, fragrance, and other analytical applications. The software is freely available through GitHub, supporting broader adoption and further development by the scientific community.</p><h3><strong>3. Shimadzu: Discrimination of Coffee Bean Species Based on Aroma Compounds</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_01123_en_c8ac025ba9.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>User Benefits</strong></h5><ul><li>Qualitative analysis of aroma compounds can be easily performed using the Smart Aroma Database.</li><li>Intuitive statistical analysis and exploration of characteristic compounds are possible using eMSTAT Solution.</li><li>The AOC -6000 multifunctional autosampler system enables the analysis of aroma compounds without sample pretreatment.</li></ul><p>Common coffee bean types are broadly classified into two types: Coffea arabica (Arabica) and Coffea canephora (Robusta). Among them, Arabica is superior in flavor and is highly favored as a specialty beverage. However, in recent years, there have been multiple reports of products sold claiming to be 100% Arabica while being adulterated with Robusta<sup>1)</sup>. A reported method for discriminating between the two is the analysis of lipophilic extracts of coffee beans using a benchtop NMR spectrometer<sup>1)</sup>. This method uses 16-O-Methylcafestol, which is present in Robusta but almost undetectable in Arabica, as a marker. However, it requires complicated pretreatment such as extraction and concentration.&nbsp;</p><p>Therefore, in this Application News, we investigated a method to discriminate between Arabica and Robusta more easily and rapidly using GC-MS/MS and the statistical analysis software eMSTAT Solution.</p><h5><strong>Sample and Analytical Methods&nbsp;</strong></h5><p>Commercially available coffee beans roasted at the same roastery were used as samples. Four brands of Arabica (Kilimanjaro, Brazil Bourbon, Mandheling G1, Brazil No.2 #18) and two brands of Robusta (Vietnam Robusta, Java Robusta) were prepared (Table 1). Each brand was individually crushed with a mill, and 1 g was weighed and sealed in a screw vial.</p><p>Volatile compounds were concentrated and introduced into the GC-MS using the HS-SPME method and then analyzed under the conditions registered in the GC-MS(/MS) Smart Aroma Database (Table 2). The <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMSTQ8040+NX"><strong>GCMS-TQTM8040 NX</strong></a> and the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=AOC-6000"><strong>AOC-6000 multifunctional autosampler</strong></a> system were used as the analytical instruments (Fig. 1). To verify whether rapid analysis is possible, a temperature ramp of 10˚C/min was adopted, and a low-polarity column was used to obtain stable retention times for each compound. Data acquisition was performed in Scan mode or MRM mode, and each sample was analyzed three times.</p><h4><strong>Exploration of Characteristic Aroma Compounds for Arabica and Robusta&nbsp;</strong></h4><p>Next, we investigated which compounds contribute to the discrimination between Arabica and Robusta. The PCA score plot (Fig. 4) reflects the differences in the tendencies of each group, with Arabica distributed on the left side and Robusta on the right side, clearly separated along the first principal component (PC1) axis. Referring to the corresponding loading plot, compounds located on the left side of the origin tend to have higher area values in Arabica, which is also positioned on the left in the score plot. On the other hand, compounds on the right side tend to show higher values in Robusta, which is located on the right in the score plot. In other words, the difference in the balance of these compoundsisthe main factorseparating the two groups. First, Arabica was commonly rich in compounds such as 5-Methyl furfural, Acetoin, and Furaneol acetate. MS chromatograms analyzed using LabSolutions Insight GCMS are shown in Fig. 7. In eMSTAT Solution, not only score plots and loading plots but also box plots can be easily drawn, making it possible to easily visualize and compare the distribution tendencies of each compound. From the box plots of the above compounds (Fig. 8), it was visually confirmed that all of them are contained in abundance in Arabica. These compounds are sometimes described as having a roasted or creamy quality, and it can be inferred that this result supports the characteristics of Arabica, which issuperior in aroma and acidity.&nbsp;</p><p>On the other hand, a compound found in abundance in Robusta was p-Vinylguaiacol. This compound is known to cause an offflavor similar to a medicinal odor in sake, and its content was low in Arabica. From this, it was suggested that p-Vinylguaiacol may be one of the compounds contributing to the bitterness and offtastes characteristic of Robusta.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>In this Application News, we investigated the discrimination of coffee bean types based on aroma compounds using the triple quadrupole gas chromatograph mass spectrometer <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=GCMSTQ8040+NX"><strong>GCMSTQ8040 NX</strong></a> and the GC-MS(/MS) <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=Smart+Aroma+Database"><strong>Smart Aroma Database</strong></a> for aroma analysis.&nbsp;</p><p>Four types of Arabica and two types of Robusta were analyzed as samples. Analysis using Scan data confirmed a tendency for the two types to separate. Subsequently, data was acquired in MRM mode, which offers higher sensitivity and selectivity, and detailed analysis was performed using the statistical analysis software eMSTAT Solution. As a result, the two groups were clearly separated in PCA and cluster analysis, demonstrating the effectiveness of discrimination by this method. Additionally, a discrimination model was developed and validated, confirming that highly accurate discrimination is possible.&nbsp;</p><p>From the above results, we conclude that the discrimination of coffee beans by aroma compound analysisis highly feasible using this method. Furthermore, this method enables a comprehensive workflow, from discrimination to the identification of characteristic compoundsfor each type.</p><h3><strong>4. Waters Corporation: Improvements to the Analysis of PBDEs in Environmental Matrices: Transitioning from EI Magnetic Sector to GC-APCI TQ MS/MS</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/720009372_7abfa9f0e9.pdf"><strong>Full PDF for download</strong></a></li></ul><p>This poster evaluates the transition of polybrominated diphenyl ether (PBDE) analysis in environmental samples from traditional electron ionization high-resolution magnetic sector GC-MS to a modern <strong>GC-APCI triple quadrupole MS/MS (GC-APCI TQ MS/MS)</strong> workflow. PBDE flame retardants are highly regulated due to their environmental persistence and potential health risks, making accurate and reliable analytical methods essential. The study investigated whether a GC-APCI MS/MS approach could match or exceed the performance of established GC-HRMS methods while offering greater flexibility and modernization opportunities.</p><p>The method was developed on a <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/554"><strong>Waters Xevo TQ Absolute mass spectrometer</strong> </a>equipped with APCI ionization and an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890"><strong>Agilent 8890 GC</strong></a>. A key innovation was the use of <strong>nitrogen as the carrier gas instead of helium</strong>, helping laboratories reduce dependence on helium supplies and mitigate increasing helium costs. By applying nitrogen flow ramping, the authors maintained chromatographic resolution and runtime comparable to the reference helium-based method without requiring changes in column dimensions. The approach also reduced the risk of thermal degradation of highly brominated compounds such as BDE 209 and achieved faster elution while preserving peak shape and separation quality.</p><p>For quantitative analysis, up to six MRM transitions per analyte were monitored, taking advantage of the characteristic isotope patterns of brominated compounds. The use of multiple transitions improved selectivity and sensitivity, while Waters waters_connect software enabled summation of MRM signals to enhance signal-to-noise ratios near detection limits. Excellent calibration performance was achieved across more than three orders of magnitude, with correlation coefficients above 0.999 for all analytes. Internal standards and recovery standards demonstrated strong reproducibility, and quality control samples showed precision typically below 15% RSD and acceptable accuracy across low, medium, and high concentration levels.</p><p>The authors conclude that an all-nitrogen GC-APCI TQ MS/MS configuration can successfully meet the performance criteria established for PBDE analysis by reference EI GC-HRMS methods. The workflow maintains critical chromatographic separations, delivers accurate quantitative results, and offers a platform that could potentially combine PBDE determination with other halogenated flame retardants in a single analytical method. These findings demonstrate that GC-APCI TQ MS/MS represents a robust and practical modernization strategy for environmental PBDE analysis.</p></div></div></div></div></div></div></section></div></div></div></div></div></div></section>

News from LabRulezGCMS Library - Week 25, 2026

Article

Events

Application

Academy

Presentation

Poster

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in industrial, government and academic laboratories.

Phenomenex

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Separation Science

Mettler-Toledo

Agilent Technologies

AZoM

LECO

Thermo Fisher Scientific

Restek Corporation

Waters Corporation

<div><h4><strong>Navigating Challenges and Opportunities for Environmental Testing Labs Under the Revised EU Water Framework Directive</strong></h4><p><strong>The European Commission’s proposed updates to the Water Framework, Groundwater, and Environmental Quality Standards Directives are bringing new responsibilities and opportunities for environmental testing labs. With expanded pollutant lists - including PFAS, pharmaceuticals, and pesticide metabolites - and stricter monitoring and reporting requirements, the landscape of water analysis is rapidly evolving.</strong></p><p>Join the 4th Waters Environmental Webinar Series to explore how your lab can navigate these challenges and turn regulatory change into opportunity.</p><p>Register for free and partner with us to shape the future of European water quality.</p><h5><strong>Why Attend</strong></h5><p>Stay ahead of new EU regulatory demands with insights from leading experts. Gain practical guidance, share experiences with peers, and prepare your lab for the next generation of water quality standards.</p><h5><strong>Highlights</strong></h5><ul><li>New pollutant categories and analytical challenges</li><li>Updates to monitoring protocols and reporting</li><li>Innovative methods to meet revised Environmental Quality Standards</li><li>Strategic guidance for compliance and adaptation</li></ul><p><strong>Lead the change in water analysis—stay ahead, stay compliant, and make a real impact.</strong></p><h4><strong>EPISODE 6: Blue Thursdays 2026 – The Best Of</strong></h4><p>In this final session, we’ll look back at the most important things we’ve learned throughout the Blue Thursday series. We’ll explore the big trends we’re seeing, the smart tools scientists use to study the environment, and what exciting developments will be coming next.</p><blockquote><p><strong>Speaker:</strong> Claudia Rathmann (Principal F&amp;E Market Development Manager, Waters Corporation)</p><p>Experienced and passionate analytical science professional with over 20 years of technical and strategic expertise in food and environmental applications. Currently serving as Principal Market Development Manager at Waters Corporation, Claudia specializes in connecting customers with product management to deliver innovative solutions for complex analytical challenges. With a strong scientific foundation and a proven track record in both technical and marketing roles, Claudia bridges the gap between customer needs and product innovation across the EMEA region.</p><p><strong>Speaker: </strong>Janitha De-Alwis (JD) (Principal F&amp;E Market Development Manager, Waters Corporation)</p><p>Janitha De-Alwis (known as JD) is an applications chemist in the European demo lab, based in Wilmslow, UK. His main role focuses on application development work for the food and environmental sector. JD takes great pride in speaking to, and advising, many food and environmental customers. His position requires him to be reactive and proactive to the changes in the food industry, such as changing regulations, topical issues and food safety risks.</p></blockquote></div>

Blue Thursdays 2026 – The Best Of

In this final session, we’ll look back at the most important things we’ve learned throughout the Blue Thursday series.

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>High-performance plastics (polymers) are the backbone of modern aerospace, medical, analytical instrumentation, and energy technologies. Because they are designed to survive extreme heat and chemicals, they are notoriously difficult to break down and study. To build better materials and ensure they don’t fail, scientists need to understand their chemical composition including the additives and “building blocks” that give them their strength.</strong></p><p>This webinar demonstrates two specialized sample delivery techniques to characterize these materials without the need for elaborate sample preparation strategies:</p><ul><li><strong>Thermal Desorption: </strong>Controlled heating (up to 300 °C) of the plastic to release additives and potential contaminants.</li><li><strong>Pyrolysis: </strong>Using intense heat (greater than 600 °C) to break the plastic’s “backbone” into identifiable fragments.</li></ul><p>Combining these techniques with high-resolution GC-TOFMS enables detection of the complex chemical fingerprints for high-performance plastics like polyether ether ketone (PEEK, used in medical implants) and polytetrafluoroethylene (PTFE, commonly known as Teflon).</p><p>We will demonstrate a reliable method to analyze the chemistry of the world’s toughest plastics. This method will help manufacturers ensure their materials are pure, and ready for use in planes, electronics, and human bodies.</p><blockquote><p><strong>Presenter: </strong>David Alonso (Applications Chemist, LECO Corporation)</p></blockquote></div></div></div>

LECO: Characterization of High-Performance Polymers Using Thermal Desorption/Pyrolysis and High-Resolution Mass Spectrometry 

Characterization of High-Performance Polymers Using Thermal Desorption/Pyrolysis and High-Resolution Mass Spectrometry 

Advanced GC-TOFMS workflows using thermal desorption and pyrolysis for chemical characterization of high-performance plastics like PEEK and PTFE.

Polymer characterization by TD/Pyrolysis & HRMS

<p><strong>PFAS &amp; Our Planet is a webinar series on PFAS testing in environmental samples, food and food contact materials, textiles and other materials. Alongside the laboratory and regulatory lens, the series addresses the broader planetary impact of PFAS, including their persistence and movement through water, soil, air, food systems, and materials. It brings together what laboratories and industry need to understand now: where PFAS rules are heading, which sample types are under increasing focus, what needs to be measured, and how those needs translate into method selection, workflow setup, and result reporting.</strong></p><h4><strong>Webinar Series Details</strong></h4><ul><li>One registration to attend the full three-part series</li><li>Questions for experts in advance and/or live Q&amp;A</li><li>Access to recorded sessions provided</li></ul><h4><strong>Who Should Attend:</strong>&nbsp;</h4><p>Environmental and water testing laboratories, food testing laboratories, food contact material and packaging laboratories, textile and materials testing laboratories, contract testing laboratories, public sector and regulatory laboratories, manufacturers of food, packaging, textiles, and consumer goods, quality, product safety, regulatory affairs, and sustainability functions, and research laboratories working on PFAS analysis.</p><h4><strong>Recommended for:&nbsp;</strong></h4><p>Analytical chemists, laboratory managers, QA/QC managers, regulatory affairs managers, food safety and product safety managers, environmental scientists, packaging and food contact materials specialists, textile and materials testing leads, sustainability and product stewardship managers, validation and method development scientists, and technical leaders in contract, public sector, and research laboratories.</p><h4><strong>Regulatory context covered:&nbsp;</strong></h4><p>EU and U.S. PFAS developments, food contact and packaging measures, environmental monitoring frameworks, OEKO-TEX requirements for textiles and materials, Singapore’s food and water surveillance activity, India’s draft PFAS-related packaging amendment, and emerging movement in parts of Southeast Asia like Thailand, Malaysia, Vietnam, Indonesia, Bangladesh and Philippines.</p><h3><strong>Textiles and Materials</strong></h3><p><strong>Textiles and treated materials are facing stronger PFAS scrutiny as product restrictions widen and supply chains are asked to verify material content more clearly. This session will cover the main external reference points shaping that shift, including the EU REACH PFAS restriction process and OEKO-TEX requirements, which have become highly relevant for textile and material suppliers serving global brands.</strong></p><p>It will then step into the laboratory workflow for textiles and related materials, covering extraction and cleanup, targeted LC/MS/MS for non-volatile PFAS, selected GC/MS/MS approaches for volatile PFAS where relevant, contamination control, and reporting formats suited to product verification. Regional context will be framed around export-market pull, buyer specifications, and certification-driven testing, which are often the main drivers for suppliers in South and Southeast Asia.</p><blockquote><p><strong>Presenter: </strong>David Saladin (Ecology Lab Team Leader, TESTEX AG, Swiss Textile Testing Institute)</p><p><strong>Presenter:&nbsp;</strong>Aimei Zou, Ph.D. (Application Scientist, Agilent Technologies, Singapore)</p></blockquote>

Agilent Technologies: PFAS & Our Planet: Textiles and Materials

PFAS & Our Planet: Textiles and Materials

PFAS in textiles webinar: regulations, LC-MS/MS and GC-MS/MS workflows, contamination control, and compliance for global supply chains.

<h3><strong>Real-Time Process Insights for Oil, Gas, &amp; Future Fuels with Raman Spectroscopy</strong></h3><h4><strong>A 5-Part Webinar Series</strong></h4><p>As the energy sector shifts toward more complex and dynamic processes, real-time analytics are essential for maintaining control, efficiency, and product quality. This 5-part webinar series explores how process Raman spectroscopy and integrated measurement solutions enable fast, in-line analysis across oil &amp; gas, power generation, and emerging energy applications.</p><h5><strong>What we'll cover:</strong></h5><p>Each session highlights practical approaches to improving process visibility, reducing analytical delays, and supporting faster decision-making for:</p><ul><li>Natural gas</li><li>Refined fuels</li><li>Hydrogen</li><li>Sustainable aviation fuels</li><li>Carbon capture</li><li>Power generation</li><li>Emerging energy applications</li></ul><h5><strong>This Series is Ideal For:</strong></h5><p>Process, operations, and instrumentation professionals across oil &amp; gas, power generation, and emerging energy sectors, including engineers, plant and refinery managers, and technical specialists involved in process optimization and analytical measurement.</p><h5><strong>Join the Webinars To:</strong></h5><ul><li>Understand how real-time, in-line analytics improve process control and efficiency</li><li>Learn how process Raman simplifies and accelerates gas and liquid analysis</li><li>Explore alternatives to traditional methods such as gas chromatography</li><li>See how integrated measurement solutions enhance operational visibility</li><li>Gain insight into applications across conventional and next-generation energy systems</li></ul><h4><strong>Webinar 5: Optimizing Future Fuel Processes with Process Raman Spectroscopy: Applications in Hydrogen, Sustainable Aviation Fuels &amp; Carbon Capture</strong></h4><p>The global transition to future fuels, such as sustainable aviation fuel (SAF), hydrogen, and carbon capture, utilization and storage (CCUS), is reshaping how energy and chemicals are produced, monitored, and controlled. Real-time analytical technologies are becoming critical to ensure process efficiency, product quality, and regulatory compliance across these emerging applications. Process Raman spectroscopy enables in-line, non-destructive measurement of complex chemical systems with minimal sample preparation.</p><p>By delivering rapid, data-rich measurements from a single scan, process Raman allows simultaneous quantification of multiple components in gases, liquids, and heterogeneous systems. This reduces reliance on slow, offline techniques and enables tighter process control and faster decision-making. The technology combines robust probe design, flexible sampling configurations, and seamless integration into industrial control systems. Its compact, field-deployable design allows deployment at multiple points from pilot to full-scale production.</p><p>This webinar will discuss the application of process Raman spectroscopy in real-time monitoring of SAF production, hydrogen isomer conversations and CCUS applications.</p><blockquote><p><strong>Speaker: </strong>Linxi Chen (Field Application Scientist, Thermo Fisher Scientific)</p></blockquote>

Thermo Fisher Scientific: Real-Time Process Insights for Oil, Gas, & Future Fuels with Raman Spectroscopy

Optimizing Future Fuel Processes with Process Raman Spectroscopy: Applications in Hydrogen, Sustainable Aviation Fuels & Carbon Capture

Join this webinar to discover how process Raman spectroscopy enables real-time analysis and process control for SAF, hydrogen, and CCUS applications.

Process Raman in Hydrogen, Sustainable Aviation Fuels

<p><strong>Discover how today’s advanced peptide technologies are shaping tomorrow’s research, development, and manufacturing success.</strong></p><h5><strong>In this symposium, you'll learn about:</strong></h5><ul><li>Scalable peptide API manufacturing and purification expertise for GLP‑1 class molecules</li><li>Label‑free, real‑time cell‑based bioassays for peptide activity, optimization, and safety testing</li><li>Non‑destructive Raman raw material identification through opaque containers to streamline GMP workflows</li><li>Inert LC/MS strategies for enhanced peptide separation, impurity profiling, and molecular weight confirmation</li></ul><p>This digital symposium explores the innovations shaping the future of peptide‑driven science, featuring modern analytical tools across cell analysis, chemistries, spectroscopy, and mass spectrometry. Experts will reveal practical approaches for integrating these technologies to strengthen and streamline peptide analysis.</p><p>Attendees will gain a clear view of emerging technologies and practical strategies across modern research and applied science. Join the symposium to discover how to connect these advances directly to your own work.</p><p><strong>10:00 - 10:05 - Intro</strong></p><p>Vitan Blagotinsek, Agilent Technologies</p><p><strong>10:05 - 10:20 - Highlight Talk - Scaling the GLP-1 Surge: Peptide API Development, Purification and Manufacturing at AAT</strong></p><p>Wolfgang Schiek, BioVectra</p><p>As the paradigm shift in diabetes management and the surge in anti-obesity drug sales and development are propelling unprecedented demand for complex peptide APIs therapies, reliable high quality peptide API manufacturing and purification are critical. Agilent Advanced Therapeutics provides specialized expertise and scaling capacity for these GLP-1 Agonists. We support our customers from preclinical to commercial through swift, customer-focused implementation in state-of-the-art facilities and are continuously expanding capabilities, true to our commitment: Invested in Science, Invested in You!</p><p><strong>10:20 - 11:05 - Talk 1: Accelerating Synthetic Peptide Discovery, Quality Control, and Safety Testing with xCELLigence Bioassay</strong></p><p>Leyna Zhao, Agilent Technologies</p><p>Synthetic peptides and proteins are rapidly emerging as important therapeutic modalities, driving the need for robust approaches to evaluate biological activity, product quality, and safety throughout development. In this webinar, we will explore how Agilent’s label free xCELLigence Real Time Cell Analysis (RTCA) platforms can support synthetic peptide discovery, quality evaluation, and safety testing through functional, cell based bioassays. Selected case studies will highlight the use of real time, kinetic cellular readouts in peptide discovery and optimization workflows. Evaluation criteria for biological products will be reviewed in the context of ICH Q6B specifications, with emphasis on the role of bioassays in assessing biological activity. In addition, examples of toxicity testing using xCELLigence RTCA—including published vaccine related applications—will demonstrate how real time cell based assays can provide sensitive and reproducible QC results.</p><p><strong>11:10 - 11:50 - Talk 2: Unlocking Deeper Insights into Peptide Purity and Impurity Profiling with LC/MS for GLP-1 RA Characterization</strong></p><p>Holger Stalz, Agilent Technologies</p><p>Synthetic Peptide therapeutics are reshaping the biopharma landscape, and GLP-1 receptor agonists are at the center of that momentum—raising the stakes for purity assessment and impurity profiling. Join this webinar to see how Agilent’s advanced LC/MS workflows help scientists tackle these challenges with greater confidence and efficiency. You’ll learn how the InfinityLab Pro iQ Plus LC/MSD enables reliable peptide purity confirmation, while the Agilent BioQTOF high-resolution LC/MS/MS system supports detailed sequence confirmation and impurity identification. We’ll also show how OpenLab CDS and MassHunter BioConfirm software simplify complex data interpretation, helping QC and R&amp;D teams move faster and make more confident decisions in peptide characterization.</p><p><strong>11:55 - 12:35 - Talk 3: Raman Spectroscopy in Peptide Pharmaceuticals</strong></p><p>Jan Wuelken, Agilent Technologies</p><p>Rapid, non destructive raw material identification (RMID) through all types of packaging. Reliable identity verification of peptides, amino acids, protected building blocks, and excipients is a critical step in peptide manufacturing. The Agilent Vaya Raman Raw Material Identity Verification System is specifically designed to identify raw materials directly through non transparent and opaque containers, without opening the package. By leveraging Spatially Offset Raman Spectroscopy (SORS), Vaya minimizes interference from container walls, liners, and fluorescence. This enables fast and reliable identification through typical peptide pharma packaging, including plastic drums, paper and multi layer bags, FIBCs, and amber glass containers. The through container measurement capability eliminates the need for sampling, significantly reducing the risk of cross contamination and protecting operators from hazardous, highly potent, or sterile materials. At the same time, it streamlines workflows by reducing handling steps and operator exposure. Agilent Vaya supports high throughput, GMP compliant raw material testing, accelerates release to manufacturing, and helps ensure a secure, efficient supply of materials for peptide synthesis and downstream processing—from early development to commercial production.</p><p><strong>12:40 - 13:15 - Talk 4: Advanced Column Solutions to enhance your Peptide Analysis and Purification Workflows</strong></p><p>Katrien Sabbe, Agilent Technologies</p><p>Whether you're optimizing existing methods or developing new ones, this session will equip you with the tools to streamline your peptide characterization and purification. LC analysis of peptides can be challenging due to their sensitivity to metal interactions within chromatographic systems, often leading to poor peak shape and reduced sensitivity. Agilent Altura HPLC columns with Ultra Inert technology overcome these challenges by minimizing metal-analyte interactions. We will illustrate how this innovation enhances resolution, reproducibility, and quantification in reversed phase and HILIC separations of therapeutic peptides such as GLP-1 receptor agonists. Furthermore we will explore preparative techniques and purification workflows, offering tips for achieving high purity and recovery in synthetic peptide purification.</p><blockquote><p><strong>Presenter: </strong>Vitan Blagotinsek (EMEA Marketing Program Manager Bio/Pharma, Agilent Technologies)</p><p>Vitan is the Agilent Marketing Manager for the Pharma and Biopharma markets across the EMEA region, covering a broad portfolio of all Agilent products with relevance to these markets. Prior to this role, he had started at Agilent as a Chromatography and Sample prep-focused Product Specialist targeting the Biopharma market in the DACH region. His scientific background is in Protein Biochemistry/Structural Biology. He graduated in Biochemistry from the University of Oxford in the UK and has a PhD from Marburg University in Germany (Department of Chemistry).</p></blockquote><blockquote><p><strong>Presenter:&nbsp;</strong>Wolfgang Schiek (Director Business Development, BIOVECTRA, Agilent Technologies)</p><p>Wolfgang is the BD Director Europe for Agilent Advanced Therapeutics, where he specializes in bespoke CDMO solutions and a chemist by profession. With a 25-year track record at industry leaders like Evonik, Cambrex, and Novasep in a variety of technical, commercial and strategic roles, he has helped numerous clients bridge the gap from drug development to successful market launch. For the past four years at AAT, he has focused on the cutting edge of biologics and peptides, serving as one of the primary forces behind the company’s GLP-1 programs.</p></blockquote><blockquote><p><strong>Presenter: </strong>Leyna Zhao (Product Marketing Director, Agilent Technologies)</p><p>Leyna is Product Marketing Director at Agilent Technologies, where she leads global strategy for cell analysis platforms, including xCELLigence Real-Time Cell Analysis (RTCA). With over 20 years of experience in molecular biology, immunology, and drug discovery, she bridges scientific innovation with market adoption. Her work focuses on advancing label-free, real-time technologies that support small molecule screening, immune cell function analysis, and predictive toxicology. She holds a PhD in Biochemistry and has been instrumental in aligning Agilent’s cell analysis solutions with emerging regulatory trends, such as non-animal testing methodologies.</p></blockquote><blockquote><p><strong>Presenter: </strong>Jan Wuelfken (Product Specialist, Molecular Spectroscopy EMEA IDO, Agilent Technologies)</p><p>Jan graduated from the University of Hamburg in 1997 with a thesis about NMR-based conformation analysis of an antimicrobial peptide and in 2001 with his PhD thesis about CD4-binding peptides as inhibitors for HIV infection. He joined Varian Inc. in 2001 as a sale representative for molecular spectroscopy and with the takeover of Varian by Agilent 2010 he became a product specialist for molecular spectroscopy in the Agilent International Distributor Organization (IDO). Today his responsibility is the full Agilent Molecular Spectroscopy Portfolio which is UV-Vis, UV-Vis/NIR, Fluorescence, FT-IR and Raman Spectroscopy.</p></blockquote><blockquote><p><strong>Presenter:&nbsp;</strong>Holger Stalz (LCMS Product Specialist, Agilent Technologies )</p><p>Holger has worked as a product specialist for LC/MS for Agilent in Austria and Switzerland since 2011. He leads a team of European BioPharma Specialists focusing on biopharmaceutical applications and has been coordinating the development of new analytical solutions and methods for protein therapeutics and oligonucleotide-based products.</p></blockquote><blockquote><p><strong>Presenter:&nbsp;</strong>Katrien Sabbe (Biopharma Business Development Manager, Agilent Technologies)</p><p>For more then 25 years Katrien has been working in the field of Chromatography Columns and Supplies, first at VWR International and later at Varian Analytical Instruments, which was acquired in 2011 by Agilent Technologies. Currently, she is the EMEA Biopharma Business Development Manager at Agilent Technologies Chemistries and Supplies Division.</p></blockquote>

BiteSizeBio: Innovations and Emerging Tools in Peptide Science

Innovations and Emerging Tools in Peptide Science

Explore advanced peptide technologies. Learn about GLP-1 API manufacturing, xCELLigence bioassays, through-container Raman RMID, and inert LC/MS workflows

Advanced Peptide Technologies and GLP-1 Analysis

<p><strong>Today’s demanding GC and GC/MS applications place increasing pressure on laboratory productivity and operating costs. While advancements in GC column inertness over the past decade have enhanced data quality, improved inertness alone is no longer sufficient for laboratories striving to remain competitive. Agilent’s premium 5Q columns build on Ultra Inert performance with added premium GC column features including enhanced thermal stability, ultra‑fast conditioning, and extended column lifetime. Join this webinar to see how these premium features can elevate your analytical performance and drive meaningful improvements in productivity.</strong></p><blockquote><p><strong>Speaker: </strong>Ashlee Gerardi (Product Marketing, Agilent Technologies, Inc.)</p><p>Ashlee Gerardi is a GC Columns Product Manager at Agilent Technologies. After receiving her B.S. in Chemistry, Ashlee began her career as an R&amp;D chemist, where she developed novel stationary phases and surface deactivations for GC columns. Ashlee then received her MBA and transitioned to business development overseeing the cannabis and hemp markets. She then served as a market manager for the chemicals, semiconductor, and mining segments.Within her current role at Agilent, Ashlee is currently working on commercializing new GC columns and workflows.&nbsp;</p></blockquote>

Agilent Technologies: Becoming a Better Chromatographer - Webinar Series

Becoming A Better Chromatographer: Understanding the Impact of Advanced GC Column Features for Improving Productivity and Data Quality in GC/MS Workflows

Improve GC/MS workflows with Agilent 5Q columns. Benefit from enhanced thermal stability, ultra-fast conditioning, and ultra-inert peak shapes

Agilent 5Q Columns for Advanced GC/MS Workflows

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Ready to modernize your dioxin analysis? Join this webinar to learn about the Orbitrap Exploris™ GC S mass spectrometer and its application in dioxin analysis for food control laboratories. The session will outline how high-resolution GC-MS with Orbitrap technology can deliver the analytical performance required for regulatory compliance. It will also consider how such approaches support the analysis of dioxins and other persistent organic pollutants in routine workflows. The presenters - Dr Kerstin Krätschmer &nbsp; (Wageningen Food Safety Research) and Dominic Roberts (Thermo Fisher Scientific), will present application data, review analytical performance against regulatory criteria, and discuss current challenges in dioxin analysis, including considerations when evaluating alternatives to traditional magnetic sector GC-HRMS systems.</strong></p><h4><strong>Learning points</strong></h4><ul><li>Learn about the new Orbitrap Exploris GC S released at ASMS 2026.</li><li>See how high-resolution GC-MS meets dioxin regulatory requirements and expands analytical capability.</li><li>Learn how to modernize workflows for simpler, future-ready dioxin &amp; POPs analysis.</li></ul><h4><strong>Who should attend?</strong></h4><ul><li>Laboratory managers, supervisors, and analysts working in food safety and environmental labs.</li><li>Analysts performing dioxin and POPs analysis interested in learning about latest technology and application approach.</li></ul><blockquote><p><strong>Presenter: </strong>Dr Kerstin Krätschmer (Head of the Dutch National Reference Laboratory for POPs, Wageningen Food Safety Research (WFSR))</p><p>Kerstin has a PhD in food chemistry and is currently head of the Dutch NRL POPs situated at Wageningen Food Safety Research (WFSR) in Wageningen, the Netherlands. She earned her PhD at the European Union Reference Laboratory for halogenated POPs in Freiburg, Germany, exploring polychlorinated alkanes analysis using GC-Orbitrap-HRAM. Within her current work as researcher in the contaminants team at WFSR, she covers a wide range of topics from PCDD/Fs to radioactivity in food, looking into new detection methods, fate in the circular food system, emerging risks and crisis preparedness.</p><p><strong>Presenter:&nbsp;</strong>Dominic Roberts (Product Marketing Manager, GC Orbitrap MS, Thermo Fisher Scientific)</p><p>Dominic Roberts has been closely involved with the Thermo Scientific GC Orbitrap MS since its launch in 2015. He started at Thermo Fisher Scientific as a Senior Applications Specialist for the product and is currently the GC Orbitrap MS Product Marketing Manager. Dominic is an experienced analytical chemist and mass spectrometrist with more than 25 years of experience using state-of-the-art analytical systems. He has worked in both a regulatory and industrial environment with GC–MS and LC–MS systems to investigate a variety of chemicals in food, biological, and environmental samples.</p></blockquote></div></div></div>

Thermo Fisher Scientific: Modernizing Dioxin Analysis for Food Control: Introducing a New GC Orbitrap

Modernizing Dioxin Analysis for Food Control: Introducing a New GC Orbitrap

Join webinar to learn about Orbitrap Exploris GC S mass spectrometer and its application in dioxin analysis for food control laboratories.

Dioxin Analysis with New GC Orbitrap

<header><p><strong>The ongoing urbanization and progressive sealing of landscapes have exacerbated surface runoff, mobilizing pollutants such as Total Suspended Solids (TSS) and microplastics (MPs), including tire and road wear particles (TRWP). The effective removal of these pollutants is imperative to meet increasingly stringent water quality regulations. Sedimentation tanks, widely deployed for the treatment of urban runoff, are often insufficient in achieving the necessary pollutant retention efficiencies, especially for particles below 63 µm. Long-term monitoring of a sedimentation tank (mixed area with pollution categories I - III, as per DWA A-102-2) in Paderborn, Germany, verified that the actual retention efficiency for TSS63 (particles &lt; 63 µm) fell significantly below the theoretical benchmark of 49,3%%, required to meet pollution category I standards. The observed inefficiency suggests that tire wear particles, which are part of the TSS, are also insufficiently retained.</strong></p><p>To address these shortcomings, we propose a novel, cost-effective, and scalable solution in the form of a microflotation-based system. This innovative technology employs controlled microbubble generation (mean diameter:45 µm) to exploit the hydrophobic properties of microplastics, facilitating their efficient separation from water. This in-situ microflotation (ISM) technology can be easily retrofitted into existing stormwater retention basins.</p><p>In this context, the focus in the presentation shown within the webinar is on the assessment of the removal of tire wear particles (TWP) in existing stormwater sedimentation tanks using in-situ microflotation. Hereby, thermal extraction desorption - gas chromatography/mass spectrometry (TGA TED-GC/MS) analysis was performed regarding the qualification and quantification of tire wear particles, as it is a state-of-the-art technology for this purpose.</p><p>Within the long-term monitoring of the sedimentation tank mentioned, TGA TED-GC/MS measurements show that tire wear retention efficiencies can be strongly increased by using microflotation.<br>Hence, the proposed system provides a benchmark for sustainable and efficient water treatment technologies, aligning with contemporary goals of resource efficiency and environmental protection.</p><h4><strong>Summary of contents</strong></h4><ul><li>Water treatment</li><li>Microplastic pollution</li><li>Qualification and quantification of tire wear particles were performed using TGA TED-GC/MS</li><li>Monitoring of sedimentation tank</li><li>Pilot-scale in-situ microflotation</li><li>Retention efficiency</li></ul><div><div data-advanced-option="false" data-has-preview-image="false" data-video-id="" data-component-id="2110920040"><div style="max-width:1px;width:100%;" id="mediaContainerWrapper_2110920040"><div style="height:1px;width:1px;" data-external-url="" id="mediaContainer_2110920040" data-advanced-option="false" data-width="1" data-height="1" data-video-id="">&nbsp;</div></div></div></div></header><div><div><div data-advanced-option="false" data-has-preview-image="false" data-video-id="" data-component-id="2110920040"><blockquote><div><strong>Presenter: </strong>Thomas Kramer (Product Manager Laboratory, Mettler-Toledo GmbH)</div></blockquote><blockquote><div><strong>Presenter: </strong>Dr. Mike Wenzel (Chemist for Microplastic Analysis, MicroBubbles GmbH)</div></blockquote><blockquote><div><strong>Presenter:</strong> Maikel Haferkamp (Application Specialist, GERSTEL GmbH &amp; Co. KG)</div></blockquote></div></div></div>

Mettler Toledo: Removal of tire wear in stormwater tanks - In Situ Microflotation with TGA TED-GC/MS Analysis

Removal of tire wear in stormwater tanks: In Situ Microflotation with TGA TED-GC/MS Analysis

Capture microplastics from urban runoff. Discover how in-situ microflotation increases tire wear retention and how TGA TED-GC/MS analyzes TRWP in water

Tire Wear Removal in Stormwater: In-Situ Microflotation

<p><strong>The word, the phenomenon, that unpleasant tingling sensation it triggers in many people’s necks. Mass spectrometry. Some love working with it; others hate it. Yet this state-of-the-art detection technique offers not only the potential for frustration, but also many opportunities and a wide range of applications in today’s world of instrumental analysis. We want to help you overcome your fears and preconceptions and show you the theory behind the technology, what the common abbreviations mean, and how you can tackle common problems more effectively with the help of our products.</strong></p><h5><strong>Key learnings:</strong></h5><ul><li>Mass spectrometry is powerful but often perceived as complex.</li><li>Understanding the basics and terminology makes MS more accessible.</li><li>The right tools help solve common MS challenges more efficiently.</li></ul>

Restek Corporation: Mass Spectrometry - Can It Really Be So Easy? 

EMEA live | Mass Spectrometry - Can It Really Be So Easy? 

Overcome the complexity of mass spectrometry. Master MS theory, understand key terminology, and learn to solve common analytical challenges

Mass Spectrometry - Can It Really Be So Easy? 

<p><strong>Discover how adopting hydrogen carrier gas maintains analytical performance and improves laboratory efficiency compared to helium.</strong></p><h5><strong>By attending this presentation &nbsp;you will:</strong></h5><ul><li>Understand the practical steps and safety considerations for converting TD-GC-MS methods to hydrogen carrier gas, including the use of on-demand generators.</li><li>Learn how to maintain method validity, spectral integrity, and regulatory compliance during the switch.</li><li>Discover how hydrogen's chromatographic properties can reduce analytical cycle times by up to 40% and increase daily sample throughput.</li><li>Review real-world case studies demonstrating consistent, reliable results across varied applications, from environmental air monitoring to routine textile testing.</li></ul><h4><strong>Event Overview</strong></h4><p>Laboratories worldwide are facing unprecedented challenges with helium carrier gas due to soaring prices and supply chain instability. As a finite resource with a high carbon footprint, helium is prompting analytical chemists to seek sustainable, cost-efficient alternatives. Hydrogen offers a proven, practical solution that can be generated on-demand.</p><p>However, transitioning a validated gas chromatography-mass spectrometry (GC-MS) method raises important questions. In this webinar, leading GC-MS experts from TESTEX, Agilent, and Markes will share their real-world experiences of migrating their GC-MS, and sample introduction systems such as thermal desorption, from helium to hydrogen. The presentation will address common analytical concerns head-on, including system safety, spectral fidelity for library matching and method validation.</p><p>The speakers will demonstrate how adopting hydrogen carrier gas maintains analytical performance and actively enhances laboratory efficiency compared to helium. Attendees will see data showcasing equivalent or increased sensitivity and chromatographic resolution, and significantly faster run times that boost overall sample throughput.</p><h4><strong>Who should attend?</strong></h4><ul><li>Laboratory managers and directors looking to control operational costs and future-proof their gas supply.</li><li>Analytical chemists and GC-MS operators seeking practical advice on method translation and validation.</li><li>Quality assurance professionals focused on maintaining regulatory compliance during instrument updates.</li></ul><h4><strong>What you need to know</strong></h4><p><strong>Start times:</strong></p><ul><li><strong>Broadcast 1:</strong> 10 am BST (London/Lisbon) / 11 am &nbsp;CEST (Paris/Berlin) &nbsp;/ 2:30 pm IST (New Delhi)</li><li><strong>Broadcast 2:</strong> 9 am PDT (Los Angeles) / 11 am CDT (Chicago) / 12 pm EDT (New York)</li></ul><p><strong>Duration:</strong> Approximately 1 hour</p><blockquote><p><strong>Presenter: </strong>Anika Maier (Technical Expert, TESTEX AG, Zurich, Switzerland)</p><p>Anika Maier is a Technical Expert at TESTEX AG in Zurich, Switzerland, an international testing and certification institute specializing in textile and leather testing, product safety, sustainability, and OEKO-TEX certifications.</p><p>Building on her background as a laboratory technician, with previous roles at Celerion and SGS Institut Fresenius, and her studies in Chemical Engineering, Anika has developed extensive expertise in gas chromatography, VOC method development, thermal desorption, and emissions testing. She is highly experienced with a wide range of instrumentation, including TD, GC-MS/MS, LC-MS/MS, HRMS, and ICP-MS.</p><p>Her current work focuses on laboratory optimization, troubleshooting analytical workflows, and driving automation and innovation projects. Notably, this includes the development and validation of analytical methods for textiles, consumer products, and chemical emissions, as well as successfully implementing hydrogen as a carrier gas for routine TD-GC-MS, GC-MS and GC-MS/MS applications.</p></blockquote><blockquote><p><strong>Presenter:&nbsp;</strong>Jess Berger (Group Product Manager, Markes, UK)</p><p>Jess is the Product Manager for the Markes Group, covering thermal desorption and sample introduction technologies for GC-MS. She joined Markes in 2012 after earning her chemistry degree from the University of Glamorgan (now the University of South Wales). Starting her career in inside sales, she progressed to become Product Manager. Jess’ extensive experience, combined with a recent MSc in International Innovation Management from the University of Wales Trinity Saint David, has given her a comprehensive understanding of the technology and its many benefits for GC analysis.</p></blockquote><blockquote><p><strong>Presenter:&nbsp;</strong>Andreas Kapaklis (<i><span>GC and GC-MS Product Specialist (CH/A), Agilent)</span></i></p><p><i><span>Dr Andreas Kapaklis is a GC and GC-MS Product Specialist for Switzerland and Austria at Agilent Technologies. Prior to joining Agilent in early 2026, he spent eight years as a Laboratory Team Leader at TESTEX in Zurich. There, he led a team of technicians and was responsible for the laboratory's GC-MS, GC-MS/MS, and GC-HRMS systems. From 2011 to 2018, he served as Head of Quality Control and Management at the Schuler wine house in Central Switzerland. He holds a PhD in the analysis of wine aroma from Justus Liebig University Giessen.</span></i><br>&nbsp;</p></blockquote>

MARKES: A Practical Guide to Switching from Helium to Hydrogen Carrier Gas

Safeguarding GC-MS Workflows: A Practical Guide to Switching from Helium to Hydrogen Carrier Gas

Future-proof your GC-MS and thermal desorption workflows. Learn how to safely switch from helium to hydrogen carrier gas and boost sample throughput by 40%.

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