The Progression of SIFT-MS Through Breath and Clinical Applications - Day 2
As any analyst will tell you, small, polar molecules are problematic.
Throw in some sulphur compounds, volatile amines, and water – you now have a “difficult analysis”. The primary reason is that traditional chromatography, both GC and LC, doesn’t really fit these compounds, leaving a gap in your analytical jigsaw puzzle. There is a third way, however – Selected Ion Flow Tube Mass Spectrometry, or SIFT-MS – which is particularly well suited to these problem analytes, and should be a natural part of your analytical toolbox.
Often, people with an awareness of SIFT-MS think of it as a niche technique, with few obvious mainstream applications. This is just not true! And, with this forthcoming event, we hope to show you why you need SIFT-MS.
Whilst the focus will be on breath, malodour and biological applications, what is clear is that laboratories that have adopted SIFT-MS, find multiple other applications where it is a valuable analytical tool and how it drives collaboration in other areas. Add into the mix, automation and you have a powerful instrument at your disposal, that will plug the hole you currently have in your laboratory. Also, it’s fast.
Day 2
13:30 – 14:30 CET: Testing Viral Filters by SIFT-MS (Eloise Bovill and Stephanie Udoh)
The impact of the COVID-19 pandemic on research activities has been immeasurable and has created unexpected challenges for researchers, however it has also been the impetus for efforts to make working with participants safer.
One piece of ongoing research examines the potential use of Vitalograph Bacterial-Viral Filters to eliminate traces of COVID-19 from breath samples. This could, in conjunction with other safety measures, allow research using breath samples to take place safely. Whilst the filters are highly effective at filtering out viruses, concerns were raised as to whether they would also filter out volatile organic compounds (VOCs).
To test this, SIFT-MS was used to measure volatile compounds produced from in-vitro biofilms inoculated with various strains of bacteria. Biofilms were sampled continuously using SIFT-MS, with and without the viral filters. This webinar will present this on-going piece of research into the use of virus-eliminating filters in breath research.
14:45 – 15:45 CET: VOCs analysis by SIFT-MS following treatment of meat by Cold Atmospheric Plasma (Alexandros Stratakos and Saliha Saad)
16:00 – 17:00 CET: Exhaled Breath Analysis Using Full-Scan SIFT-MS Data: development of chemometric approaches and clinical potential (P.-H. Stefanuto, D. Zanella, J. Vercammen, M. Henket, F. Schleich, R. Louis, J.-F. Focant)
