Univocal Identification of Flavor and Fragrance Compounds Using GC-MS (TOF) / Condensed Phase FTIR with an Extensive Library
To obtain a univocal identification we need three independent pieces of analytical information. Flavor and fragrance components are usually separated by gas chromatography and identified with MS spectral comparison and linear retention indices (LRI). However, diastereomeric or positional isomers can present identical retention behavior and MS spectra, and can cause misidentification. The development of a unique condensed-phase FTIR provides the solution - a simple post-column split combines it with a GC-MS instrument, using the GC to separate the components and MS (TOF) and FTIR spectrometers to give structural elucidation in a single analysis.
Learning Objectives of Webinar
- When GC-MS in not enough: unique condensed phase GC-FTIR.
- Importance of the linear retention index (LRI) in the identification procedure.
- Comprehensive flavor and fragrance MS (TOF) / FTIR library: application for real essential oil and perfume samples.
Presenter: William W. Carson, PE, Chief Technology officer, DANI Instruments INC
Developer of scientific and biotech separation, analysis and purification systems. He has led highly successful start-up through Fortune 500 groups developing and commercializing chromatography, membrane and hyphenated spectroscopy systems. Bill’s 30+ issued US Patents have generated over $1 Billion in sales. In 1986 he received the Millipore Prize for Innovation. In 2008 he was the winner of the R&D 100 Award for the development of the DiscovIR LC a direct deposition, desolvation system which hyphenated HPLC to FTIR.
Presenter: Margita Utczás, PhD, Product manager Libraries, Chromaleont srl
Margita Utczás graduated in 2007 in Chemical engineering, then in 2009 in Biomedical engineering and in 2013 she received a PhD in Chemical Sciences at the Budapest University of Technology and Economics. She was a post doctoral fellow at the University of Messina and later worked at Chromaleont as a GC-MS specialist. She has just become the responsible of the analytical department of the Center of Sports Nutrition Science at the University of Physical Education of Budapest and currently she is an external consultant of her former workplace, Chromaleont. Her main research interests include: supercritical extraction and enzymatic resolution techniques, gas chromatographic techniques coupled to mass spectrometry and FTIR and their applications to the study of bioactive and flavor and fragrance compounds.
