Removing Barriers in Non-target GC/MS for the Confident Identification of Unknowns
Conventional GC-HRMS using EI data alone for non-target studies suffers from ambiguous identification of unknowns in NIST library searches due to less specific fragmentation, missing molecular ion signals or compound absence in the reference library. Library searches become prone for false positive assignment. To increase compound identification certainty, the addition of the molecular information, e.g., via CI is mandatory.
See how a novel GC-HRMS approach with simultaneous EI and CI data acquisition in a single GC run dramatically improves the quality of information and identification certainty. Non-target studies in wastewater analysis, human metabolites, vegan food similarity and material emission prove a game-changing power of the system.
Why to join this webinar:
- Understand the power of simultaneous EI and CI-HRMS data in single GC runs
- Learn how to get to a safe and confident identification of unknowns in suspect and non-target GC-MS
- Get to know a novel CI source with unmatched performance due to a wide selection of reagent ions and “zero” instrument downtime
- Accelerate your analysis and post-processing time plus optimize your instrument uptime with no need of hardware switching
Presenter: Arnd Ingendoh (VP Business Development Applied Markets, Bruker Daltonics GmbH & Co KG)
Arnd Ingendoh received his PhD in biophysics 1994 in the group of Franz Hillenkamp and Michael Karas who developed and invented MALDI. Following two years at ThermoFisher and Bruker in Japan and the USA as an application specialist, he moved through various management positions at Bruker Daltonics in Germany with +15 years of service as Senior Vice President for Commercial Operations EMEA.
After 25 years at Bruker, he changed to a start-up company from New Zealand, Syft Technologies, to build the European commercial organization as the Vice President Europe for real-time mass spectrometry applications like air monitoring, food quality testing and monitoring of industrial processes. In 2023, he rejoined Bruker as the VP Business Development for the Applied Mass Spectrometry division. His goal is to develop and introduce novel and potentially disruptive technologies for the applied markets. Aside of his commercial activities, Arnd had active roles in academic education, e.g. as a Guest Professor at the University of Vienna. He is author or co-author of more than 60 publications.
Presenter: Sonja Klee (Produkt Manager ecTOF, TOFWERK AG)
Dr. Sonja Klee is Product Manager at TOFWERK, a leading mass spectrometer manufacturer based in Switzerland. Her journey in mass spectrometry began during her undergraduate studies in Chemistry at the University of Wuppertal, Germany, where she delved into ionization and mass spectrometry fundamentals in the group of Thorsten Benter. Both fundamental research and practical applications continued through her academic studies with her PhD in Physical Chemistry in 2014 on chemical ionization mechanisms in mass spectrometry for which she received the Wolfgang-Paul-Study Award of the German Society for Mass Spectrometry (DGMS). Following this, Dr. Klee was awarded a Postdoctoral Marie Curie Fellowship to contribute to the CLOUD TRAIN Network at CERN, Switzerland.
Focus of this tenure was conducting complex experiments within the EU research program "CLOUD" utilizing various TOFWERK mass spectrometers. After her two-year postdoctoral position, she continued with TOFWERK, leveraging her expertise in ionization and mass spectrometry development in several key roles, including Leading Coordinator for Ion Source Technology and Project Manager. Dr. Klee's extensive research background and industrial experience have significantly contributed to the development and introduction of the ecTOF product line, a breakthrough solution for GC-MS based compound identification. Recognized for her expertise and leadership in the field, Dr. Klee was elected as an official board member of the Swiss Group for Mass Spectrometry (SGMS) in 2023. Here, she manages the "Education" portfolio, reflecting her commitment to advancing knowledge and innovation in mass spectrometry.
