<blockquote><p>Welcome back to the topic of protecting your GC column! <strong>If you missed part 1</strong> or would like to refresh your knowledge, find further tips on GC column protection <a target="_blank" rel="noopener noreferrer" href="https://www.phenomenex.com/knowledge-center/gc-knowledge-center/protecting-your-gc-column-pt1-tech-tip-en-1025"><strong>here</strong>.</a></p></blockquote><p><strong>Protecting your GC column and instrument components from exposure to dirty samples or contaminants is important. Non-volatile or high molecular weight components can contaminate the stationary phase, causing poor peak resolution, lower accuracy, and poor column lifetime. Cutting off the damaged portion of column tubing will often restore your column’s performance, but over time performance will degrade to a point where the column can no longer be used. If you are experiencing rapid degradation of column performance, there are several simple ways to help protect your column and increase its lifetime.</strong></p><h3><strong>Use A Liner With Wool</strong></h3><p>The liner is the first line of defense for your column, and the style you choose can make a big impact in how much contamination gets onto the column. The easiest thing to do is to add a small amount of silanized glass wool to a liner, which traps the non-volatile compounds and prevents them from entering directly into the column.&nbsp;</p><blockquote><p><strong>Caution: </strong>glass wool can also add activity for acids, bases, and pesticides. Crushing the glass wool can expose undeactivated glass and free silanols (-OH groups) even if the wool has been deactivated. This leads to increased activity, so pre-packed liners, rather than self-packed ones are highly recommended to avoid reproducibility issues.</p></blockquote><p>In addition to choosing a liner with wool, ensure that your liner (and other system consumables) are free of contaminant build-up that may form over time. Septum cores and other particulates that remain can become trapped in the wool and are sometimes difficult to spot. Regularly replace the liner (and other system consumables as needed) to reduce troubleshooting and maintenance.</p><h3><strong>Bake Out Your Column</strong></h3><p>The easiest way to reduce column contamination is to add a short, high temperature bake-out at the end of your standard GC method. This bake out helps remove high boiling contaminants that would otherwise remain in the column and cause damage. To bake out, the final oven temperature needs to be set high enough to ensure elution of these compounds, but not so high as to cause thermal damage. This can be done either isothermally, or more commonly, via an oven ramp until the last components elute from the column. Caution: NEVER exceed the upper temperature limits of your column. DO NOT exceed more than fifteen minutes at the upper isothermal temperature limit specified for the column.</p>

How to Protect Your GC Column - Part 2

<p>🎤 <strong>Presenter</strong>: Christopher Freye (Los Alamos National Laboratory)</p><p>💾 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_1_Freye_10783a9cf3.pdf"><strong>PDF presentation</strong></a></p><h3><strong>Abstract</strong></h3><p><strong>Two-dimensional gas chromatography (</strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=2"><strong>GC×GC</strong></a><strong>) when coupled with mass spectrometry (MS) especially high-resolution mass spectrometry (HRMS) provides the ideal technique to discover minute chemical changes. However, GC×GC analyses result in extremely large datasets (GBs of information) wherein the statistically significant chemical changes are buried within the background chemical matrix. To combat these issues, many chemometric techniques have been developed or applied. Recently we introduced a new chemometric technique for GC-MS termed alteration analysis (ALA) and two-dimensional correlation (2DCOR) which can be used to discover statistically significant chemical changes across a series of chromatograms and understand the relationship between the statistically relevant changes. ALA generates three sets of information, the basic alteration map (BAM) which is the magnitude of the change, the synchronous alteration map (SAM) which describes the linear change, and the asynchronous alteration map (AAM) which describes the non-linear change. 2DCOR can then be used to understand the relationship between the chemical changes but 2DCOR can also resolve the sequence of the changes. A workflow for GC×GC-MS will be demonstrated. Special attention will be given to what differentiates the GC×GC work flow from GC for both the ALA and 2DCOR.</strong></p><h3><strong>Video Transcription</strong></h3><p>The presentation focuses on how <strong>advanced mathematical and chemometric methods</strong> can be used to extract meaningful information from <strong>highly complex chromatographic data</strong>, especially in <strong>multidimensional chromatography coupled with mass spectrometry (GC×GC-MS, LC-MS)</strong>.</p><h4><strong>Why traditional data analysis falls short</strong></h4><p>Modern multidimensional chromatography generates <strong>extremely large datasets</strong>, often containing <strong>billions of data points</strong>. Visual inspection, peak tables, or classical identification-based workflows are impractical—especially when:</p><ul><li>Samples are highly complex (e.g. petroleum, metabolomics, high explosives)</li><li>Most compounds are <strong>unknown unknowns</strong></li><li>The key question is not <i>what</i> the compounds are, but <strong>whether samples differ and how</strong></li></ul><p>Program managers and decision-makers are primarily interested in <strong>detecting statistically significant changes</strong>, not exhaustive compound identification.</p><h4><strong>Introduction of Alteration Analysis (ALA)</strong></h4><p>To address subtle, trend-based changes across series of chromatograms, the speaker introduces <strong>Alteration Analysis (ALA)</strong>, a chemometric approach adapted from spectroscopy and applied to chromatography.</p><p>ALA quantitatively evaluates how <strong>individual data points change across multiple samples</strong>, allowing detection of:</p><ul><li>Extremely subtle trends</li><li>Overlapping peaks</li><li>Changes hidden in noise or baseline interference</li></ul><p>Key ALA outputs include:</p><ul><li><strong>BAM (Basic Alteration Map):</strong> magnitude of change</li><li><strong>SAM (Systematic Alteration Map):</strong> linear changes</li><li><strong>AM (Alteration Map):</strong> nonlinear changes</li></ul><p>Even changes as small as <strong>1% per sample</strong> can be detected reliably, including peaks that are heavily overlapped.</p><h4><strong>Beyond detection: understanding relationships with 2D Correlation</strong></h4><p>Once statistically significant changes are identified, <strong>two-dimensional correlation analysis (2D-COR)</strong> is used to understand <strong>relationships between changing compounds</strong>, including:</p><ul><li>Whether compounds are correlated or anti-correlated</li><li>The <strong>sequence of changes over time</strong> (which changes happen first)</li></ul><p>This is especially critical for <strong>degradation and aging studies</strong>, where intermediate species may appear and disappear before the final state—information that traditional methods like Fisher ratio or PCA often miss.</p><h4><strong>Solving GC×GC challenges with tiling</strong></h4><p>GC×GC data introduces additional challenges due to:</p><ul><li>Peak misalignment</li><li>Exponential data growth during correlation calculations</li></ul><p>The presenter explains how <strong>tile-based approaches</strong> reduce data dimensionality, overcome alignment issues, and make ALA and 2D correlation computationally feasible—even for massive GC×GC-MS datasets.</p><h4><strong>Real-world application: explosive aging studies</strong></h4><p>The methodology was applied to <strong>aging and decomposition of high explosives</strong>, where:</p><ul><li>Over <strong>250 chemical changes</strong> were identified</li><li>Many intermediate species would have been missed using traditional comparisons</li><li>ALA combined with 2D correlation enabled reconstruction of <strong>degradation pathways</strong></li><li>The most significant change was <strong>not necessarily the first change</strong>, a critical insight for risk assessment and stability studies</li></ul><h4><strong>Key takeaway</strong></h4><p>By combining <strong>Alteration Analysis and 2D correlation</strong>, the approach:</p><ul><li>Detects statistically guaranteed chemical changes</li><li>Handles subtle, overlapped, and noisy signals</li><li>Determines <strong>magnitude, type, interrelationships, and order of changes</strong></li><li>Shifts chromatographic data analysis from identification-driven to <strong>decision-driven</strong></li></ul><p>This math-driven workflow enables faster, more reliable interpretation of complex chromatographic datasets and provides actionable insights for applications such as <strong>explosive aging, pharmaceutical degradation, and complex mixture analysis</strong>.</p><blockquote><p><strong>This text has been automatically transcribed from a video presentation using AI technology. It may contain inaccuracies and is not guaranteed to be 100% correct.</strong></p></blockquote>

Discovery analysis for GCxGC trends using alteration and 2D correlation (Chris Freye, MDCW 2026)

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 9th February 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you technical note by <strong>Agilent Technologies, </strong>presentation by<strong> MDCW / University of Copenhagen </strong>and<strong> </strong>application notes by<strong> Shimadzu </strong>and<strong> Thermo Fisher Scientific!</strong></p><h3><strong>1. Agilent Technologies: What Causes Spots on </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?instrumentationItems=19&amp;manufacturerItems=1&amp;search=PLOT"><strong>PLOT Columns</strong></a><strong>? Will It Affect the Performance of the Column?</strong></h3><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/te_what_causes_spots_plot_columns_affecting_performance_5994_8775en_agilent_3b7180512a.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Spots on porous layer open tubular (PLOT) columns are caused by small voids in the stationary phase coating inside the tube. These spots are areas where there is an uneven coating or lack of phase. It is normal to find some voids in the phase coating of PLOT columns. The stationary phase in PLOT columns is an opaque, solid, and porous material. In many Agilent PLOT columns such as the GS-Alumina phases, molecular sieves, porous polymers (Q and U), and the GS-OxyPLOT, the stationary phase is visible as a white powder. For many PLOT columns, the stationary phase fill solution is a viscous suspension of particles that are less than 10 microns in diameter. The phase is coated using a dynamic process in which a plug of fill solution is pushed through the tubing, and the plug’s speed and viscosity determines the thickness of the stationary phase layer. Once the PLOT’s stationary phase is deposited, it is held in place by electrostatic charge, chemical interactions between particles, and/or binding agents. In wall‑coated open tubular (WCOT) columns, stationary phases such as polysiloxanes or polyethylene glycols are immobilized by chemical bonding to the glass surface and cross-linking between polymer strands. Because this type of bonding and cross‑linking is not possible with PLOT phases, the result is a stationary phase layer that is both fundamentally different and inherently less stable in PLOT columns than in WCOT&nbsp;columns.</p><h3><strong>2. MDCW / University of Copenhagen: One-shot tensor decomposition of full-scale GC×GC-VUV datasets for resolving petrochemical groups</strong></h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_17_Schneide_67c8ff7866.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The presentation introduces a novel <strong>all-samples-at-once, shift-invariant tri-linear tensor decomposition approach</strong> for the analysis of full-scale <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?search=GC%C3%97GC-VUV"><strong>GC×GC-VUV</strong></a><strong> datasets</strong>, aimed at resolving and quantifying petrochemical groups. Traditional template-based or pixel-based methods struggle with retention-time shifts and co-eluting compounds, often requiring manual intervention and prior chemical knowledge. The proposed approach leverages the intrinsic low-rank structure of GC×GC-VUV data to enable robust, automated group-level analysis across multiple samples simultaneously.</p><p>At the core of the method is a <strong>shift-invariant tri-linear model</strong>, conceptually related to PARAFAC and multivariate curve resolution, but extended using frequency-domain (FFT-based) modeling to explicitly account for chromatographic peak shifts. By decomposing the entire dataset in one step, the model provides <strong>accurate estimates of peak landscapes, VUV spectra, and relative peak areas</strong>, while remaining agnostic to retention-time variability. Importantly, the approach requires only a small number of tunable parameters, making it practical for routine use.</p><p>The method was demonstrated on a <strong>case study involving 14 petrochemical gas-oil samples</strong>, including straight-run, hydrotreated, hydroconverted, coker, and light cycle oils. Extracted VUV spectra showed excellent agreement with reference spectra from a VUV spectral database, enabling confident assignment of components to chemical groups such as saturates, olefins, and mono- to poly-aromatics. Quantitative results exhibited <strong>high repeatability (RSD typically 3–9%)</strong> and strong correlation with established template-based reference methods.</p><p>Overall, the work demonstrates that <strong>one-shot, shift-invariant tensor decomposition</strong> provides a powerful and scalable alternative to conventional GC×GC data-analysis strategies. By combining chemical interpretability, robustness to chromatographic shifts, and strong quantitative performance, the approach opens new opportunities for automated, high-confidence group-level analysis of complex petrochemical samples and beyond.</p><h3><strong>3. Shimadzu: Py-Screener Ver. 3: Simultaneously Test for Substances Regulated Under RoHS, TSCA, and POPs</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00949_en_4754e50164.pdf"><strong>Full PDF for download</strong></a></li></ul><h5><strong>User Benefits</strong></h5><ul><li>In just one analysis, <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=3&amp;search=Py-Screener"><strong>Py-Screener</strong></a> Ver. 3 can determine levels of phthalate esters, brominated flame retardants (PBBs, PBDEs), PIP (3:1), UV-328, dechlorane plus (DP), short-chain chlorinated paraffins (SCCPs), and medium-chain chlorinated paraffins (MCCPs).&nbsp;</li><li>It can also test for SCCPs and MCCPs by electron ionization (EI) instead of negative chemical ionization (NCI).&nbsp;</li><li>PIP (3:1), UV-328, DP, and SCCPs and MCCPs can be screened without the need for corresponding reference materials.</li></ul><p>Countries and regulatory bodies worldwide are introducing increasingly stringent regulations on the chemical substances used in electronic devices and industrial products. The RoHS Directive and REACH regulations in the EU, the Toxic Substances Control Act (TSCA) in the USA, and the Stockholm Convention on Persistent Organic Pollutants (POPs) are also targeting an increasingly broad range of substances. Therefore, manufacturers are required to accurately identify regulated substances in their products and comply with each regulation. While Py-Screener Ver. 2 can screen for seven phthalate esters and brominated flame retardants, including substances regulated under the RoHS Directive, version 3 can also screen for PIP (3:1), which is regulated under the TSCA, as well as UV328, DP, and SCCPs and MCCPs , which are regulated under the Stockholm Convention on POPs. A list of supported substances isshown in Table 1. This article introduces the simultaneous analysis of multiple regulated substances and a case study of testing specific regulated substances in samples, using Py-Screener Ver. 3.</p><h4><strong>Analysis Process</strong></h4><p>Py-Screener Ver. 3 can determine levels of phthalate esters and brominated flame retardants contained in products in accordance with the international analytical standards IEC62321-8 and IEC62321-3-3. It can also test for specific regulated substances (Table 1) under the same conditions and in the same analysis. In this test, background intensity and instrument sensitivity (S/N) were verified before analyzing samples. These parameters are prescribed by IEC62321-8 to ensure the accuracy of the methods used. Background intensity and instrument sensitivity were determined using a reference material (PN: 225-31003- 91) *1 that consisted of a plastic sheet that was spiked with seven phthalate esters. The results met the criteria for both parameters.</p><p>The testing workflow is shown in Fig. 1. Before testing samples, calibration curves were prepared by analyzing the 1000 mg/kg phthalate ester reference material and polypropylene spiked with brominated flame retardants (ERM-EC591). A hole puncher was used to punch out two discs at a time of the phthalate ester reference material, and a cutter was used to obtain pieces of the other materials. Each material was weighed in a sample cup for analysis. During the analysis of samples, phthalate esters and some of the regulated brominated flame retardants were quantitated using a one-point calibration curve. The remaining brominated flame retardants and specific regulated substances were quantitated using the correction factor database*2 that is included with Py-Screener Ver. 3.</p><h4><strong>Conclusion</strong></h4><p>Py-Screener Ver. 3 successfully determined in samples the concentrations of the regulated substances PIP (3:1), UV-328, DP, and SCCPs and MCCPs. Normally, SCCP and MCCP levels are tested using NCI, but Py-Screener Ver. 3 uses EI. This enables it to test for not only SCCPs and MCCPs but also phthalate esters, brominated flame retardants, and other regulated substances in just one analysis. In addition, by using the relative correction factors linked to DEHP in the phthalate ester reference material, the levels of these regulated substances were determined without the need for the corresponding reference materials. Py-Screener Ver. 3 can also create a screening program that addresses substance restrictions under the RoHS Directive, the US TSCA, and the POPs Convention.</p><h3><strong>4. Thermo Fisher Scientific: Improving low carbon steel production in specialty steel processes</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/prima_pro_process_mass_spectrometer_an1626_7fc840235f.pdf"><strong>Full PDF for download</strong></a></li></ul><p>World crude steel production reached 1,691 million tonnes in 2017, up by 5.3% compared to 2016.1 While much of this capacity is still produced in primary steel processes such as basic oxygen furnaces and electric arc furnaces, the need for refined steel with greater durability and resistance to heat and corrosion has led to the increased use of vacuum degassing processes, such as VOD and RH, in secondary steel production. These processes are able to achieve ultra-low levels of residual carbon, while at the same time retaining desired levels of other alloy materials. If these processes are to achieve the required level of steel product quality, they need fast, continuous gas analysis of the furnace exhaust gas. Without accurate information on the composition of the gas leaving the furnace, any variations in the decarburization process are only detected after the event, resulting in the production of out-of-specification steel.</p><h4><strong>Advantages of mass spectrometry&nbsp;</strong></h4><p>Traditional Non-Dispersive Infra-Red (NDIR) analyzers are used in many conventional steelmaking processes to measure CO and CO<sub>2</sub> , but they can only sample at atmospheric pressure. In vacuum steelmaking the process pressure changes dramatically, typically from atmospheric pressure down to less than 1 mbar, over the 20-30 minutes of the melt. So NDIR analyzers have to sample some distance downstream from the process. Analytical data is updated several minutes after the gas leaves the melt and the control system is forced to operate on historic rather than real-time data.&nbsp;</p><p>Paramagnetic analyzers can be used to measure O<sub>2</sub> , while thermal conductivity analyzers can be used to measure H<sub>2</sub> . These analyzers also suffer from slow response, while the need to operate three different types of analyzers adds to the plant maintenance burden. Moreover, the three analyzers cannot analyze inert gases, so N<sub>2</sub> is calculated by difference, a result that suffers from the sum of the errors of the three analytical techniques.&nbsp;</p><p>Mass spectrometry operates at high vacuum so it is ideal for monitoring vacuum processes. It is also able to monitor all seven components in Table 1 in seconds rather than minutes, ensuring the plant control model is frequently updated with accurate compositional data.</p><h4><strong>Precision of analysis&nbsp;</strong></h4><p>At the heart of the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?manufacturerItems=2&amp;search=Prima+PRO+Mass+Spectrometer"><strong>Thermo Scientific™ Prima PRO Mass Spectrometer</strong></a> (MS) is a magnetic sector analyzer which offers unrivalled precision and accuracy compared with other mass spectrometers. Thermo Fisher Scientific manufactures both quadrupole and magnetic sector mass spectrometers; over thirty years of industrial experience have shown the magnetic sector based analyzer offers the best performance for industrial on-line gas analysis.&nbsp;</p><p>Key advantages of magnetic sector analyzers include improved precision, accuracy, long intervals between calibrations, and resistance to contamination. Typically, analytical precision is between 2 and 10 times better than a quadrupole analyzer, depending on the gases analyzed and complexity of the mixture.&nbsp;</p><p>A unique feature of the Prima PRO magnet is that it is laminated. Its analysis times are similar to a quadrupole analyzer, offering the unique combination of rapid analysis and high stability. This allows the rapid and extremely stable analysis of an unlimited number of user-defined gases. The scanning magnetic sector is controlled with 24-bit precision using a magnetic flux measuring device for extremely stable mass alignment.&nbsp;</p><p>The ion source is an enclosed type for high sensitivity, minimum background interference, and maximum contamination resistance. This is a high-energy (1000 eV) analyzer that offers extremely rugged performance in the presence of gases and vapors that have the potential for contaminating the analyzer. Typical performance specifications for the Prima PRO MS are shown in Table 1. Analytical performance is demonstrated by analyzing the calibration bottle over 1 hour following calibration, with an analysis time of just 6 seconds. Standard deviations measured on the calibration cylinder will be equal to or better than the stated values.</p>

News from LabRulezGCMS Library - Week 07, 2026

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Thermo Scientific TraceGOLD™ TG-WaxMS GC Columns

Analyze FAMEs with excellent thermal stability using the Thermo Scientific™ TraceGOLD™ TG-WaxMS GC Column.

<p><strong>Analyze FAMEs with excellent thermal stability using the Thermo ScientificTM TraceGOLDTM TG-WaxMS GC Column.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Polar phase, polyethylene glycol</li><li>Polar-deactivated surface that tightly binds polymer for excellent thermal stability</li><li>Resistive to oxidative damage and damage from strongly acidic or basic volatiles better than silicone solid phases<br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1331/817;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_Wax_MS_GC_columns_8ee57e55f2/Pragolab-GC-kolona-TraceGOLD-TG-WaxMS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-WaxMS GC Columns" width="1331" height="817"></figure><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Aldehydes</li><li>Essential oils</li><li>Solvents</li><li>Xylenes</li></ul><h4><strong>Alternative Uses:</strong></h4><ul><li>Acids</li><li>Alcohols</li><li>Alcohols in beverages</li><li>Alditol acetates (sugars)</li><li>Amines–Aliphatic</li><li>Amines–Aromatic</li><li>Herbicides</li><li>Ketones</li><li>Nitroaromatics</li><li>Phenols</li><li>Volatiles</li></ul><h4><strong>Applications:</strong></h4><ul><li>Fatty acid methyl esters (FAMEs)</li><li>Flavor compounds and essential oils</li><li>Solvents</li><li>Xylene isomers</li><li>EPA Method 603 for Acrolein/Acrylonitrile</li></ul><h4><strong>Similar to:</strong></h4><ul><li>DB-WAX</li><li>DB-WAXetr</li><li>HP-Wax</li><li>HP-Innowax</li><li>SUPELCOWAX™ 10</li><li>CP-Wax 52 CB</li><li>Stabilwax™</li><li>Rtx™-Wax</li><li>BP20</li><li>ZB-Wax</li><li>Optima™ Wax</li><li>AT™-Wax</li></ul>

Thermo Scientific TraceGOLD™ TG-WaxMS A GC Columns

Identify organic acids with high performance, sensitivity and reproducibility while preventing oxidative damage using Thermo Scientific™ TraceGOLD™ TG-WaxMS A GC column.

<p><strong>Identify organic acids with high performance, sensitivity and reproducibility while preventing oxidative damage using Thermo Scientific™ TraceGOLD™ TG-WaxMS A GC column.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Polar phase, acid-deactivated polyethylene glycol</li><li>Resists oxidative damage and adsorption of acids</li><li>Excellent peak shapes for high MW acids</li><li>Equivalent to USP G25, G35 phases<br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1305/798;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_Wax_MS_A_GC_columns_c81b8bbcb3/Pragolab-GC-kolona-TraceGOLD-TG-WaxMS-A-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-WaxMS A GC Columns" width="1305" height="798"></figure><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Acids</li><li>Carboxylic acids</li><li>Organic acids</li></ul><h4><strong>Alternative Uses:</strong></h4><ul><li>Alcohols</li><li>Alcohols in beverages</li><li>Aldehydes</li><li>Alditol acetates (sugars)</li><li>Essential oils</li></ul><h4><strong>Applications:</strong></h4><ul><li>Organic acids</li><li>Free fatty acids</li><li>Alcohols</li></ul><h4><strong>Similar to:</strong></h4><ul><li>DB-FFAP</li><li>HP-FFAP</li><li>Nukol™</li><li>OV™-351</li><li>CP-Wax 58 CB</li><li>Stabilwax™-DA</li><li>BP-21</li><li>Optima™ FFAP</li></ul>

Thermo Scientific TraceGOLD™ TG-WaxMS B GC Columns

Identify basic analytes with high performance, sensitivity, and reproducibility without derivatization or column priming using Thermo Scientific™ TraceGOLD™ TG-WaxMS B columns.

<p><strong>Identify basic analytes with high performance, sensitivity, and reproducibility without derivatization or column priming using Thermo Scientific™ TraceGOLD™ TG-WaxMS B columns.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Polar, base-deactivated polyethylene glycol phase</li><li>Reduced absorption and improved responsiveness for basic compounds</li><li>Not suitable for use with water or alcohols</li></ul><p><br>&nbsp;<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_Wax_MS_B_GC_columns_5941c8d641/Pragolab-GC-kolona-TraceGOLD-TG-WaxMS-B-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-WaxMS B GC Columns" width="1331" height="798"></p><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Amines–Aliphatic</li><li>Amines–Aromatic</li></ul><h4><strong>Alternative Uses:</strong></h4><ul><li>Alcohols</li><li>Alcohols in beverages</li><li>Aldehydes</li><li>Alditol acetates (sugars)</li><li>Essential oils</li></ul><h4><strong>Similar to:</strong></h4><ul><li>CAM</li><li>Carbowax™ Amine</li><li>CP Wax51</li><li>Stabilwax™-DB</li></ul>

Thermo Scientific TraceGOLD™ TG-POLAR GC Columns

Refine your expectations for high-polarity GC/MS with the Thermo Scientific™ TraceGOLD™ TG-POLAR columns, which are specifically designed with a polymer and surface treatment

<p><strong>Refine your expectations for high-polarity GC/MS with the Thermo Scientific™ TraceGOLD™ TG-POLAR columns, which are specifically designed with a polymer and surface treatment to overcome traditional problems with high-polarity columns.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Highly polar phase, 90% biscyanopropyl/10% phenylcyanopropyl polysiloxane, not bonded</li><li>Strong dipole moment and high selectivity for cis/trans compounds or compounds with conjugated double bonds</li><li>Equivalent to U.S.P G8 and G48</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_POLAR_GC_columns_1372b3e395/Pragolab-GC-kolona-TraceGOLD-TG-POLAR-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-POLAR GC Columns" width="1305" height="798"></p><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Applications:</strong></h4><ul><li>Cis/Trans fatty acid methyl esters (FAMEs)</li><li>Dioxins</li></ul><h4><strong>Alternative Uses:</strong></h4><ul><li>Alcohols</li><li>Aldehydes</li><li>Biodiesel–FAMEs</li></ul><h4><strong>Similar to:</strong></h4><ul><li>DB-23</li><li>HP-23</li><li>Rtx™™-2330</li><li>SP™-2330</li><li>SP™-2380</li><li>SPB™-2560</li><li>HP-88</li><li>Silar™™ 90c</li><li>CP-Sil 88 FAME</li><li>CP-Sil 88</li><li>BPX 70</li><li>BPX 90</li></ul>

Thermo Scientific TraceGOLD™ TG-XLBMS GC Columns

Choose Thermo Scientific TraceGOLD™ TG-XLBMS GC Column which offer a low-polarity, low-bleed column suitable for a wide range of applications.

<p><strong>Choose these columns which offer a low-polarity, low-bleed column suitable for a wide range of applications.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Proprietary stationary phase</li><li>Unique selectivity</li><li>Max. temperature: 340/360 °C</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Pesticides</li><li>PCB congeners</li><li>PAH's</li></ul><h4><strong>Application:</strong></h4><ul><li>Aroclor Mixes Analysis</li><li>GC/MS for PCB Congeners</li><li>GC/MS for PAHs</li><li>GC/MS for Aroclor Mixes</li></ul>

Thermo Scientific TraceGOLD™ TG-VRX GC Columns

Thermo Scientific™ TraceGOLD TG-VRX GC Columns provide good resolution and fast analysis times for volatile compounds.

<p><strong>Thermo Scientific™ TraceGOLD TG-VRX GC Columns provide good resolution and fast analysis times for volatile compounds.</strong></p><ul><li>Proprietary stationary phase</li><li>Optimized dimensions for analysis of volatile organic pollutants</li><li>Ideally suited for US EPA Methods 502.2, 524.2, 8021, and 8260</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Volatile organic pollutants</li><li>Aromatics</li></ul><h4><strong>Application:</strong></h4><ul><li>Volatile Organic Pollutants Analysis</li><li>GC/MS for US EPA Method 8021 Compounds</li></ul><h4><strong>Similar to:</strong></h4><ul><li>DB-VRX</li><li>Rtx-VRX</li></ul>

Thermo Scientific TraceGOLD™ TG-VMS GC Columns

Thermo Scientific™ TraceGOLD TG-VMS GC Columns provide good resolution and fast analysis times for volatile compounds.

<p><strong>Thermo Scientific™ TraceGOLD TG-VMS GC Columns provide good resolution and fast analysis times for volatile compounds.</strong></p><ul><li>Proprietary stationary phase</li><li>Optimized dimensions for analysis of volatile organic pollutants</li><li>Ideally suited for US EPA Method 8260B</li><li>Max. temperature: 260 °C</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Volatile organic pollutants</li></ul><h4><strong>Application:</strong></h4><ul><li>Volatile Organic Pollutants Analysis</li><li>GC/MS for US EPA Method 8260B Compounds</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx-VMS</li></ul>

Thermo Scientific TraceGOLD™ TG-OCP I and II GC Columns

Analyze organochlorine pesticides and herbicides with ultralow bleed, superior sensitivity, excellent peak shape using Thermo Scientific™ TraceGOLD™ TG-OCP I and TG-OCP II GC columns.

<p><strong>Analyze organochlorine pesticides and herbicides with ultralow bleed, superior sensitivity, excellent peak shape and the highest levels of reproducibility using Thermo Scientific™ TraceGOLD™ TG-OCP I and TG-OCP II gas chromatography columns.</strong></p><h4><strong>Redefining Your Expectations for Gas Chromatography:</strong></h4><ul><li>Low bleed with excellent signal-to-noise ratio, sensitivity and mass spectral integrity</li><li>Fast analysis time to facilitate full separation of chlorinated pesticides</li><li>Ideal for U.S. EPA methods 8081, 608 and CLP</li></ul><h4><strong>Proprietary Formulation Facilitates Analysis of Difficult Compounds:</strong></h4><ul><li>The acidic nature of the silanol groups prevalent within many GC columns can result in the adsorption of basic compounds, which frequently leads to peak tailing.</li><li>In TraceGOLD GC columns, basic functional groups are bonded onto the column surface to reduce the effects of tailing and improve run-to-run reproducibility and sensitivity.</li></ul><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended Use:</strong></h4><ul><li>Organochlorine pesticides</li><li>Herbicides</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx™-CLPesticides</li><li>Rtx™-CLPesticides2</li></ul>

Thermo Scientific TraceGOLD™ TG-OPP I and II GC Columns

Analyze organophosphorus pesticides with ultralow bleed, superior inertness, and consistent reproducibility using Thermo Scientific™ TraceGOLD™ TG-OPP I and II GC Columns.

<p><strong>Analyze organophosphorus pesticides with ultralow bleed, superior inertness, and consistent reproducibility using Thermo Scientific™ TraceGOLD™ TG-OPP I and II GC Columns. This column's low bleed delivers excellent signal-to-noise ratio, sensitivity, and mass spectral integrity. Expect full separation of organophosphorus pesticides with a fast analysis time. TraceGOLD TG-OPP I and II GC Columns are ideal for U.S. EPA methods 8141A.</strong></p><h4><strong>Redefines Expectations for Gas Chromatography:</strong></h4><ul><li>Low bleed, delivering excellent signal-to-noise ratio, sensitivity and mass spectral integrity.</li><li>Fast analysis time, facilitating full separation of organophosphorus pesticides.</li><li>Ideal for U.S. EPA methods 8141A</li></ul><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended Use:</strong></h4><ul><li>GC/MS for Organophosphorus Pesticides</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx™-OPPesticides</li><li>Rtx™-OPPesticides2</li></ul>

Thermo Scientific TraceGOLD™ TG-ALC Plus II GC Columns

Perform fast, full separation of blood alcohols and other volatile compounds by headspace gas chromatography using Thermo Scientific™ TraceGOLD™ TG-ALC GC columns.

<p><strong>Perform fast and full separation of blood alcohols by headspace gas chromatography (GC) using Thermo Scientific™ TraceGOLD™ TG-ALC GC columns.&nbsp;</strong></p><p>These columns are also ideal for analysis of other volatile compounds including abused inhalant anesthetics, γ-hydroxybutyrate (GHB), γ-butyrolactone (GBL), glycols, and common industrial solvents. TraceGOLD TG-ALC columns have low bleed for excellent signal-to-noise ratio, sensitivity, and mass spectral integrity.&nbsp;</p><p><strong>Note:</strong> Blood alcohol analysis requires dual column confirmation when using GC-FID</p>

Products distributed by Thermo Fisher Scientific (EMEA) - page 8

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