<p><strong>The international standard ISO/IEC 17025 [1] clause 7.7.2 with regards to ensuring the validity of results, requires a laboratory to participate in proficiency testing (PT) and/or to participate in interlaboratory comparisons (ILCs) other than PT. However, no guidance as to what these other ILCs might be, or indeed how they might compare in relation to PT, is provided. This leaflet aims to outline other ILCs available, pointing out some of the limitations as compared to PT.&nbsp;</strong></p><p>There are three major types of ILCs in which a group of laboratories analyses identical portions from a homogeneous, stable test sample, with each type being characterized by its intended purpose [2,3]:</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_2_d9263807fb.jpg" alt="Eurachem: Interlaboratory comparisons other than proficiency testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_2_d9263807fb.jpg 245w," sizes="100vw" width="1507" height="607"></p><p>A key point is that PT is an ILC that is designed to specifically evaluate the performance of participants, providing them with an infrastructure to monitor and assess the validity of their results. This is not the key purpose of the two other ILCs, and thus depending on their intended purpose they have a number of limitations that laboratories need to be aware of when using them rather than PT. Only proficiency testing should have been conducted in full compliance to the competency standard ISO/IEC 17043 [4].&nbsp;</p><h4><strong>Evaluation of measurement procedure performance&nbsp;</strong></h4><p>These ILCs, are designed to assess how a particular measurement procedure performs and whether it is fit for its intended purpose. These ILCs are often referred to as a ‘method performance study’ or a ‘collaborative study’ [2]. Some limitations of using such ILCs for monitoring laboratory performance as an alternative to PT are:&nbsp;</p><ul><li>All participants use the same measurement procedure i.e. the measurement procedure that is being validated. Unless the measurement procedure is being routinely used by the participating laboratory such an ILC will not assess the routine performance of the laboratory using their own routine measurement procedure. Nor does it enable them to compare their performance with other laboratories using alternative measurement procedures.&nbsp;</li><li>The measurement procedure is likely to be new, so participants may not have established stable procedures and quality control, so performance may not reflect routine use.&nbsp;</li><li>The report from such an ILC would not provide information on the performance of the participant, if the statistical model used makes the assumption that all laboratories perform with equal variability.</li><li>The design of the study may require the participants to assess multiple samples and/or to undertake multiple replicate analysis on the test materials. This may not be representative of the routine measurements or tests undertaken by the laboratory.&nbsp;</li><li>The conclusion of the ILC might be that the measurement procedure being assessed is not valid.&nbsp;</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_3_a53ecd2f5d.jpg" alt="Eurachem: Interlaboratory comparisons other than proficiency testing" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Eurachem_Interlaboratory_comparisons_other_than_proficiency_testing_3_a53ecd2f5d.jpg 157w," sizes="100vw" width="570" height="566"></p><h4><strong>Characterisation of candidate reference materials&nbsp;</strong></h4><p>These are ILCs that assign a property value to a candidate reference material, usually with a stated measurement uncertainty. These are often referred to as a ‘material certification study’ [2]. Limitations of using such ILCs as an alternative to PT are:&nbsp;</p><ul><li>The analysis of the candidate reference material is likely to require additional care in exercising the routine measurement procedure, such as substantially more replication, and/or may require quite different reporting formats (e.g. all valid replicates instead of a mean result). Thus, such an ILC will not necessarily provide an evaluation of the performance of the laboratory based on the routine use of their measurement procedures.&nbsp;</li><li>The report from such an ILC may include the results from the participating laboratories but would not provide information on the performance of each laboratory.&nbsp;</li><li>Participating laboratories may be required to assess multiple samples and/or to undertake multiple replicate analysis on the candidate reference materials. Thus this may not be representative of the routine measurements or tests undertaken by the laboratory.&nbsp;</li></ul><h4><strong>Other ILCs&nbsp;</strong></h4><p>Some other ILCs, whilst not being conducted in full compliance of the requirements of ISO/IEC 17043, may be designed to evaluate participant performance. These would include small ILCs as defined by EA‑2/21 [5] or split sample ILCs i.e. where a portion of a single sample is sent to two or three laboratories. Whilst these ILCs are specifically designed to evaluate participant performance, they may not provide a comprehensive comparison that a PT might provide. In such cases the laboratory needs to evaluate carefully the competence of the organization managing the ILC and the suitability of the service externally provided (ISO/IEC 17025 clause 6.6).</p>

Interlaboratory comparisons other than proficiency testing

RI Calibration in NIST26 Chromatogram and Applying to Calculating RI in Samples

<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 29th June 2026? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><strong>LabRulezICPMS</strong></a> libraries.</p></blockquote><p>This week we bring you application note by <strong>Agilent Technologies, </strong>presentation by <strong>MDCW / William &amp; Mary </strong>and posters by <strong>Shimadzu</strong> and <strong>Thermo Fisher Scientific</strong> <strong>/ ASMS!</strong></p><h3><strong>1. Agilent Technologies: Residual Solvents Analysis Based on the 2025 USP &lt;467&gt; and Chinese Pharmacopoeia (ChP 0861)</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/br_8890b_gc_5994_9205en_agilent_fb5db29527.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p><strong>Using the </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8697"><strong>Agilent 8697 headspace sampler</strong></a><strong> and </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890B"><strong>Agilent 8890B GC system</strong></a></p><p>Residual solvents are routinely introduced during pharmaceutical manufacturing as part of synthesis, purification, or formulation processes. Because these volatile organic compounds may pose toxicological risks, their levels must be carefully monitored to ensure patient safety and regulatory compliance. As a result, residual solvent analysis remains a critical component of quality control throughout the pharmaceutical development and manufacturing lifecycle.&nbsp;</p><p>USP &lt;467&gt; provides a harmonized framework for residual solvent analysis, defining solvent classifications, concentration limits, and analytical requirements.1 In September 2025, USP &lt;467&gt; was revised to reflect updated toxicological evaluations and regulatory expectations. The revised chapter expanded the class 2B solvent list and introduced performance requirements for newly added compounds, including tertiary butyl alcohol and cyclopentyl methyl ether (CPME). These updates increase the analytical scope of residual solvent testing and place greater emphasis on consistent system performance and suitability verification. In China, residual solvent control is governed by General Chapter 0861 of the Chinese Pharmacopoeia (ChP 0861)2 , which adopts a risk based classification system consistent with the International Council for Harmonisation (ICH) Q3C.3 Although the Chinese Pharmacopoeia uses different terminology for analytical procedures, its regulatory intent, solvent classification, and control principles are harmonized with USP &lt;467&gt;.&nbsp;</p><p>Gas chromatography with headspace sampling is widely used for residual solvent determination due to its robustness and suitability for volatile analytes. Alongside evolving regulatory requirements, modern GC systems have increasingly focused on intelligent operation to support method execution and compliance. The Agilent 8890B gas chromatograph incorporates GC Assist to help users perform a performance check of the GC system. When performance criteria are not met, the GC system provides alerts to notify the user. Upon user instruction, the GC can initiate a guided troubleshooting workflow, supporting step-by-step fault diagnosis through autonomous diagnostic functions, helping both experienced and less experienced analysts resolve issues efficiently during routine operation. In this application note, a headspace GC/FID method is presented for the determination of class 1, 2A, and the expanded class 2B residual solvents. This study demonstrates how updated regulatory requirements can be addressed using an intelligent GC platform that supports reliable system performance assessment, simplified troubleshooting, and consistent analytical performance.</p><h4><strong>Experimental</strong></h4><p>The experimental conditions described in this study follow the general chromatographic principles outlined in USP &lt;467&gt; procedures A and B. They are also consistent with the recommended headspace GC methods described in ChP 0861. In this work, the screening and confirmation concepts of procedures A and B were implemented simultaneously through a dual-column, dual-FID/GC configuration. Samples were introduced by an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8697"><strong>Agilent 8697 headspace sampler</strong></a> to an <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=10&amp;search=8890B"><strong>8890B GC</strong></a> and equally split to an Agilent DB-Select 624 UI and a DB-WAX UI column for parallel detection, as shown in Figure 1. Comparable chromatographic performance was achieved with both helium and nitrogen carrier gases. Data were acquired using Agilent OpenLab CDS version 2.8, and noise was determined using a peak-to-peak (PtoP) approach for calculation of signal-to-noise ratios for target analytes.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>This application note demonstrates a harmonized headspace GC/FID workflow suitable for residual solvent analysis in compliance with both the 2025 revision of United States Pharmacopoeia (USP) &lt;467&gt; and the Chinese Pharmacopoeia (ChP 2025, General Chapter 0861). By implementing a dual‑column, dual-FID configuration on a single inlet, screening and confirmatory analyses can be performed simultaneously, significantly reducing total analysis time compared to traditional sequential approaches while maintaining orthogonal separation selectivity. The integrated Agilent 8697 headspace sampler and 8890B GC platform provides consistent chromatographic performance with both helium and nitrogen carrier gases, supporting flexible laboratory operation without compromising data quality. Beyond analytical performance, the intelligent capabilities of the 8890B GC enhance operational reliability and simplify daily use. Through continuous interaction with the user, the built‑in GC Assist function operates in a guided, wizard‑like manner, leading users step by step through the troubleshooting process for effective fault diagnosis. Together, these features enable a compliant, time-efficient, and user-friendly solution for residual solvent testing under the latest USP &lt;467&gt; and ChP&nbsp;0861 requirements.</p><h3><strong>2. MDCW / William &amp; Mary: Developing a Combined Approach to Green Gunshot Residue Analysis in the Forensic Laboratory</strong></h3><ul><li>Presentation</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_24_Saunders_f2c5bcdb20.pdf"><strong>Full PDF for download</strong></a></li></ul><section><div><div><div><div><div><div><p>Developing a Combined Approach to Green Gunshot Residue Analysis in the Forensic Laboratory presents a multidisciplinary strategy for improving the forensic analysis of <strong>"green" gunshot residue (GSR)</strong>, which originates from lead-free ammunition. Traditional GSR analysis relies heavily on the detection of lead, barium, and antimony particles using scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDS). However, environmentally friendly ammunition replaces these heavy metals with more common elements, making conventional forensic protocols less effective. The authors therefore propose combining inorganic GSR (IGSR) characterization by SEM-EDS with organic GSR (OGSR) analysis using comprehensive two-dimensional gas chromatography coupled with mass spectrometry (GC×GC-MS).</p><p>The presentation first describes the development of a new SEM-EDS characterization strategy tailored to green GSR particles. Instead of relying solely on the elemental composition defined by existing OSAC guidelines, the approach incorporates both particle morphology and elemental complexity. In parallel, the researchers optimized an extraction procedure for organic residues and developed a dedicated GC×GC-MS method. Method optimization focused on key chromatographic parameters such as inlet temperature, modulation period, carrier gas selection, and oven temperature program. Compared with previously published methods, the optimized workflow provided higher peak capacity, improved analyte resolution, and enhanced detection of characteristic OGSR compounds.</p><p>To verify the analytical performance, the optimized GC×GC-MS method was evaluated using several reference standards, including phthalates, nitroaromatic explosives, nitroglycerin, and a multi-component gun surveillance standard. The resulting two-dimensional chromatograms demonstrated excellent separation and clear identification of compounds relevant to firearm discharge residues, confirming that the method can reliably detect a broad range of organic GSR markers. The combination of enhanced chromatographic separation with mass spectrometric detection offers substantially greater resolving power than conventional one-dimensional GC-MS, making it particularly valuable for complex forensic samples.</p><p>The authors conclude that integrating SEM-EDS with GC×GC-MS provides a more comprehensive approach to modern GSR analysis, particularly for lead-free ammunition. The study successfully established a characterization strategy for inorganic green GSR, optimized extraction and chromatographic conditions for organic GSR, and verified the visibility and identification of target analytes using certified standards. Future work will focus on further method validation, incorporating retention indices and sorbent-based extraction techniques, and strengthening the scientific robustness of the approach to support forensic evidence under <strong>Rule 702</strong>, thereby improving the reliability and courtroom acceptance of green GSR analyses.</p><h3><strong>3. Shimadzu / ASMS: Impact of Soil Matrix on Microplastics Analysis by Py-GC/MS</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/TP_222_Impact_of_Soil_Matrix_on_Microplastics_Analysis_by_Py_GCMS_63fdb8ef7d.pdf"><strong>Full PDF for download</strong></a></li></ul><p>The matrix is not just background—it actively participates in pyrolysis chemistry. Lignin-rich soils can co-pyrolyze, producing compounds that overlap with common PS or PVC markers, complicating interpretation. Matrix variability is substantial, with clear chemical and physical differences between forest soils, agricultural land, river sediments, and landfill cover materials. Soil particles act as sinks and sorbents, interacting with microplastics and altering degradation pathways. Sample preparation can introduce bias, and in some cases does more harm than good.&nbsp;</p><p>In this poster, we present a method to improve quantitative accuracy in Py-GCMS microplastics analysis by assessing the matrix effect, while also addressing key challenges in the qualitative identification</p><h4><strong>Experimental Methods&nbsp;</strong></h4><ul><li>Three soil samples were collected from different locations (Figure 1) and homogenized using a mortar/pestle.&nbsp;</li><li>From each sample, 200g were dried in a vial for 3 hours at 40C and 2mg was weighed into a PY cup.&nbsp;</li><li>Targeted microplastics include PE, PP, PS, ABS, PMMA, PC, PVC, N6, and N66. The percentage distribution of polymers in the MPs-CaCO3 standard, as well as the mass of each analyte in a 4 mg standard within a CaCO3 diluent, is shown in Figure 1.&nbsp;</li><li>These were analyzed using a <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library?mainauthorItems=1&amp;search=Py-GC%2FMS"><strong>PY-GCMS instrument</strong></a>, shown in Figure 2.&nbsp;</li><li>A 5-point calibration curve was prepared, in triplicate, by weighing 0.2mg, 0.4mg, 0.8mg, 2.0mg, and 4.0mg from Frontier’s Low calibration standard mix of microplastics.&nbsp;</li><li>A matrix-matched calibration curve was generated by spiking sample B with the same concentration as the calibration levels.&nbsp;</li><li>Samples were analyzed, and analytes in the sample were quantified in µg, calculated using the calibration curve of known standard concentration.&nbsp;</li><li>Recovery studies were performed in blank samples to evaluate matrix effect for the targeted analytes. For this, a 2mg sample was weighed in triplicate, and 2mg of the standard mix was combined with 2mg of CaCO3 diluent.</li></ul><h4><strong>Conclusions</strong></h4><p>Future work will focus on improving microplastic identification by using multiple markers to reduce false positives, while advancing polymer identification tools and spectral libraries to better handle high-background matrix interferences.</p><p>Sample preparation is an important factor, and it needs to be considered and studied for different sample types, including environmental and clinical samples</p><h3><strong>4. Thermo Fisher Scientific / ASMS: Untargeted analysis of volatile PFAS in indoor air by thermal desorption GC high resolution </strong><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/472"><strong>Orbitrap Mass Spectrometer</strong></a></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/po_004717_lsms_volatile_pfas_air_exploris_gc_efs_po004717_asms2026_na_en_69541bd1e3.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Per- and polyfluoroalkyl substances (PFAS) are persistent “forever chemicals” widely used in consumer products and commonly detected in indoor air. Volatile PFAS can originate from treated materials and degrade into harmful compounds linked to adverse health effects. Thermal desorption (TD) enables efficient air monitoring by preconcentrating volatile compounds for direct GC-MS analysis. Coupling TD with high-resolution Orbitrap GC-MS and advanced data processing allows comprehensive, untargeted screening of PFAS, supporting improved indoor air quality assessment.</p><h4><strong>Materials and methods</strong></h4><h5><strong>Sample preparation&nbsp;</strong></h5><ul><li>PFAS standards prepared in methanol and spiked onto sorbent tubes</li><li>Indoor air sampled (35 L) from carpeted, non-carpeted, and cleaning storage areas&nbsp;</li><li>Air collected using sorbent tubes with pumped sampling (TD-compatible). Test method(s)&nbsp;</li><li>Samples analyzed using thermal desorption (TD)–GC-MS (<a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/472"><strong>Orbitrap Exploris GC</strong></a>)&nbsp;</li><li>TD preconcentration followed by GC separation and HRAM full-scan acquisition (EI/CI)&nbsp;</li><li>Method enabled untargeted screening of volatile compounds.&nbsp;</li></ul><h5><strong>Data analysis&nbsp;</strong></h5><ul><li>Data processed using <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/76"><strong>Thermo Scientific Chromeleon CDS</strong></a>, FreeStyle, and <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/1759"><strong>Compound Discoverer Software&nbsp;</strong></a></li><li>Workflow included peak detection, deconvolution, and library matching.</li></ul><h4><strong>Conclusions&nbsp;</strong></h4><ul><li>TD-GC Orbitrap MS enables sensitive, untargeted detection of volatile PFAS in indoor air with minimal sample preparation&nbsp;</li><li>HRAM data combined with advanced software workflows provides confident identification and efficient data filtering&nbsp;</li><li>Higher PFAS levels observed in carpeted and cleaning areas, highlighting indoor sources and exposure risk</li></ul></div></div></div></div></div></div></section></div></div></div></div></div></div></section>

News from LabRulezGCMS Library - Week 27, 2026

Article

Application

Academy

Video

Software

Poster

Eurachem is a European network promoting international traceability of chemical measurements and good analytical practice. It provides expert guidance, supports method validation, uncertainty evaluation, proficiency testing, and facilitates discussion on technical and policy issues in analytical quality.

Eurachem

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

LabRulez

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures.

James Little/Mass Spec Interpretation Services

Organomation NiGen GC/HC Nitrogen Generator

The NiGen GC/HC is available in both a basic and HC version which completely removes hydrocarbons using a Pt/Pd catalyzer. 

<p><strong>The NiGen GC/HC is available in both a basic and HC version which completely removes hydrocarbons using a Pt/Pd catalyzer. It is capable of distributing 500 mL/min with greater than 99.9995% purity. It's designed to be connected to a dedicated AirComp compressor (can be purchased separately).&nbsp;</strong></p><p><strong>Parallel connection</strong> allows for up to <strong>4 generators </strong>to be stacked in a tower configuration. It features a CPU with touch screen display, which can be linked to a generator using <strong>CAN-BUS</strong>. This enables monitoring of the operating status and provides access to the maintenance menu, alarm reports, and functional parameters. It is capable of supporting up to <strong>12 FIDs</strong> or <strong>NPDs </strong>with makeup gas or up to <strong>7 ECDs</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Organomation_Ni_Gen_GC_modular_configuration_75ae60afb0.jpg" alt="Organomation: NiGen GC - Modular configuration" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Organomation_Ni_Gen_GC_modular_configuration_75ae60afb0.jpg 147w," sizes="100vw" width="727" height="768"></p><h4><strong>Standard features</strong></h4><ul><li>Modular configuration</li><li>Capacity to supply up to 12 FIDs/NPDs with makeup gas, or up to 7 ECDs or 5 S/S</li><li>Easy, "plug and play" integration with the dedicated Brezza series air compressor AirComp</li><li>Included Fast Start technology guarantees UHP after only 30 minutes</li><li>HC model includes Pt/Pd to remove up to .1ppm of THC</li><li>CPU with Touch Screen Display (connectable with CAN BUS) allows you to monitor the operational status</li><li>CPU also has an Ethernet output for PC connection&nbsp;</li></ul><h4><strong>Specification</strong></h4><p><strong>Key Features:</strong></p><ul><li><strong>Flow Rate:</strong> 500 mL/min</li><li><strong>Output Pressure:</strong> 0 – 87 PSI (0 – 6 bar)</li><li><strong>Purity:</strong> &gt; 99.9995%</li><li><strong>Total Hydrocarbons:</strong> &lt; 0.1 ppm (HC model only)</li></ul><p><strong>Air Input Requirements:</strong></p><ul><li><strong>Particulates:</strong> ≤ 0.01 mm</li><li><strong>Oil Vapors:</strong> ≤ 0.01 mg/m³</li><li><strong>Moisture:</strong> ≤ 3 °C dew point (ATP)</li><li><strong>Minimum Pressure:</strong> 8 bar</li><li><strong>Flow Rate:</strong> 6 L/min</li></ul><p><strong>Electrical Requirements:</strong></p><ul><li><strong>NiGen GC:</strong> 115/230 V ±10%, 50–60 Hz, 50 W</li><li><strong>NiGen GC HC:</strong><ul><li>115 V ±10%, 60 Hz, 200 W</li><li>230 V ±10%, 50 Hz, 200 W</li></ul></li></ul><p><strong>Additional Specifications:</strong></p><ul><li><strong>Protection Index:</strong> IP20</li><li><strong>Noise Level:</strong><ul><li>&lt; 50 dBA for 98% of operation</li><li>&lt; 60 dBA briefly during cycling</li></ul></li><li><strong>Operating Temperature:</strong> 40 °F to 100 °F (5 °C to 40 °C)</li><li><strong>Environmental Humidity:</strong> Max 90% (non-condensing)</li><li><strong>Maximum Altitude:</strong> 2000 m (6561.68 ft)</li></ul><p><strong>Dimensions &amp; Weight:</strong></p><ul><li><strong>GC Model:</strong><ul><li>Height: 15.8" (40 cm)</li><li>Weight: 63 lbs (28 kg)</li></ul></li><li><strong>GC HC Model:</strong><ul><li>Height: 18.6" (47 cm)</li><li>Weight: 70.5 lbs (32 kg)</li></ul></li><li><strong>Width:</strong> 14.9" (38 cm)</li><li><strong>Depth:</strong> 20.8" (53 cm)</li></ul><p><strong>Pneumatic Connections:</strong></p><ul><li>Compressed Air Inlet: G 1/8” female</li><li>Nitrogen Outlet: G 1/8” female</li></ul><p><strong>Warranty: </strong>2 years</p><h4><strong>Accessories</strong></h4><ul><li>AirComp oil free compressor</li><li>CPU: User interface with touch screen display Brezza version</li><li>Installation kit</li><li>Maintenance kit for 8,000 or 16,000 running hours</li></ul>

Organomation NITRO-GEN Nitrogen Generator

The NITRO-GEN generator was developed with Organomation’s nitrogen evaporators in mind to provide nitrogen generation for sample concentration.

<p><strong>The NITRO-GEN generator was developed with Organomation’s nitrogen evaporators in mind to provide nitrogen generation for sample concentration. The generator is lightweight and easy to set up, requiring only a source of compressed air to run. This unit is an ideal choice for labs with an in-house compressed air source.</strong></p><p>The generator uses a hollow-fiber membrane to convert compressed air to a stream of 95-99% pure nitrogen gas. The hollow-fiber membrane consists of a series of narrow, semipermeable tubes in a porous membrane. As compressed air travels through the fibers, oxygen and water vapor permeate the membrane and are vented off, leaving a steam of high purity nitrogen gas. At up to 99% purity, the resulting nitrogen gas stream can be used in a variety of sample preparation applications.</p><h4><strong>NITRO-GEN</strong></h4><p>The NITRO-GEN produces up to 20 L/min of nitrogen gas and is recommended for evaporation of up to 48 sample positions.&nbsp;</p><h4><strong>Standard features</strong></h4><ul><li>Adjustable outlet pressure regulator, 0-100 psi</li><li>Dual Stage clean air filtration system</li><li>Requires an oil-less compressed air source</li></ul><h4><strong>Advantages</strong></h4><ul><li><strong>Quick Start-Up Time </strong>- Nitrogen is produced instantly, no heat up time</li><li><strong>Saves Energy </strong>- No electrical power needed</li><li><strong>Engineered Design </strong>- Life expectancy is more than 10 years</li><li><strong>Low Maintenance </strong>- Serviceable clean air filter</li><li><strong>Compact and Lightweight </strong>- Small footprint conserves valuable bench space</li><li><strong>Reduced CO2 Emissions </strong>- No heaters, less energy required</li></ul><h4><strong>Specification</strong></h4><h5><strong>Key Features:</strong></h5><ul><li><strong>Flow Rate:</strong> Up to 20 L/min</li><li><strong>Technology:</strong> Hollow-fiber membrane</li><li><strong>Output Pressure:</strong> Adjustable 0 – 100 PSI</li><li><strong>Electrical Requirements:</strong> None (no power required)</li><li><strong>Noise Level:</strong> &lt; 40 dBA (virtually silent when connected to an instrument)</li></ul><h5><strong>Inlet Air Requirements:</strong></h5><ul><li><strong>Maximum Inlet Pressure:</strong> 150 PSI (10.3 bar)</li><li><strong>Particulate Filtration:</strong> ≤ 0.01 µm</li><li><strong>Oil Vapor Content:</strong> &lt; 0.01 mg/m³ (&lt; 0.01 ppm)</li><li><strong>Relative Humidity:</strong> &lt; 100% (non-condensing)</li><li><strong>Air Quality:</strong> Clean, contaminant-free air</li></ul><h5><strong>Environmental Conditions:</strong></h5><ul><li><strong>Operating Temperature:</strong> 36–122 °F (2–50 °C)</li><li><strong>Ambient Pressure:</strong> Atmospheric</li></ul><h5><strong>Dimensions &amp; Weight:</strong></h5><ul><li><strong>Size (W × D × H):</strong> 9.5 × 8 × 19.5 in (241 × 203 × 495 mm)</li><li><strong>Weight:</strong> 13.25 lbs (6 kg)</li></ul><p><strong>Warranty: </strong>1 year</p>

Linde REDLINE Pressure Regulators C 200/1 & C 200/2

REDLINE C 200 pressure regulators provide precise and stable gas control up to 6.0 purity, ideal for laboratory, analytical, and research applications.

<p><strong>The REDLINE C 200 series pressure regulators (models C 200/1 single-stage and C 200/2 dual-stage) are designed for precise control of non-corrosive gases with purity levels up to 6.0 (99.9999%), as well as gas mixtures containing low concentrations of corrosive components.</strong></p><p>These regulators ensure excellent pressure stability, high accuracy, and preservation of gas purity, making them ideal for demanding laboratory, analytical, and research applications.</p><p>The C 200/1 single-stage version is suitable for applications with stable inlet pressure, such as gases supplied in liquid phase. The C 200/2 dual-stage version is specifically designed for systems where inlet pressure fluctuates, ensuring highly stable outlet pressure even under changing conditions.</p><h4><span><strong>Key Features</strong></span></h4><ul><li>High precision pressure regulation for analytical applications</li><li>Suitable for high-purity gases up to grade 6.0 (99.9999%)</li><li>Excellent outlet pressure stability (especially dual-stage version)</li><li>Designed to maintain gas purity and minimize contamination</li><li>Wide range of configurable outlet pressure ranges</li><li>Flexible configuration with multiple valve and purging options</li><li>Robust and reliable design for laboratory and R&amp;D environments</li></ul><h4><span><strong>Technical Specifications</strong></span></h4><ul><li><strong>Inlet pressure:</strong> up to 230 bar</li><li><strong>Outlet pressure ranges:</strong><ul><li><i>C 200/1 (single-stage):</i> 3 / 6 / 10 / 14 / 16 / 28 / 35 / 50 / 100 / 200 bar</li><li><i>C 200/2 (dual-stage):</i> 1 / 3 / 6 / 10 / 14 bar</li></ul></li><li><strong>Gas compatibility:</strong><ul><li>Non-corrosive gases up to purity 6.0</li><li>Gas mixtures with low corrosive content</li></ul></li><li><strong>Inlet connections:</strong><ul><li>According to DIN 477 and gas specification</li></ul></li><li><strong>Outlet connections:</strong><ul><li>Compression fittings</li><li>Hose nozzles</li></ul></li></ul><h4><span><strong>Available Configurations</strong></span></h4><h5><span><strong>Models</strong></span></h5><ul><li><strong>C 200/1 (Single-stage)</strong><br>Designed for applications with stable inlet pressure</li><li><strong>C 200/2 (Dual-stage)</strong><br>Designed for fluctuating inlet pressure with maximum outlet stability</li></ul><h4><span><strong>Optional Equipment</strong></span></h4><ul><li>Shut-off valve (Type A)</li><li>Needle valve (Type B)</li><li>High-pressure side purge (Type P)</li><li>Inert/external gas purge (Type TP)</li><li>Purge manifold (Type EP)</li><li>Post-purge (Type DP – available only for C 200/2)</li></ul><h4><span><strong>Applications</strong></span></h4><ul><li>Laboratory gas supply systems</li><li>Analytical instrumentation (e.g., GC, LC, MS workflows)</li><li>Research and development environments</li><li>High-purity gas distribution systems</li><li>Any application requiring stable pressure and contamination-free gas delivery</li></ul>

Linde REDLINE Pressure Regulators C 300/1 & C 300/2

REDLINE C 300 pressure regulators provide precise and stable gas control up to 6.0 purity, ensuring reliability for laboratory, analytical, and research applications.

<p><strong>The REDLINE C 300 series pressure regulators (models C 300/1 single-stage and C 300/2 dual-stage) are designed for precise control of non-corrosive gases with purity levels up to 6.0 (99.9999%), as well as gas mixtures containing low concentrations of corrosive components.</strong></p><p>Thanks to their robust design and high-quality manufacturing, these regulators provide excellent pressure stability, accuracy, and long-term reliability. They are particularly well suited for demanding laboratory, analytical, and research applications where maintaining gas purity and consistent pressure is critical.</p><p>The C 300/1 single-stage regulator is recommended for applications with relatively stable inlet pressure, such as gases supplied in liquid phase. The C 300/2 dual-stage version is intended for systems with fluctuating inlet pressure, ensuring highly stable outlet pressure and improved control under varying operating conditions.</p><h4><span><strong>Key Features</strong></span></h4><ul><li>Precise and stable pressure regulation for analytical workflows</li><li>Compatible with high-purity gases up to grade 6.0 (99.9999%)</li><li>Dual-stage version provides superior outlet pressure stability</li><li>Designed to maintain gas purity and minimize contamination risks</li><li>Wide range of adjustable outlet pressure settings</li><li>Modular design with multiple optional valve and purge configurations</li><li>High reliability for continuous laboratory and R&amp;D operation</li></ul><h4><span><strong>Technical Specifications</strong></span></h4><ul><li><strong>Inlet pressure:</strong> up to 300 bar</li><li><strong>Outlet pressure ranges:</strong><ul><li><i>C 300/1 (single-stage):</i> 3 / 6 / 10 / 14 / 16 / 28 / 35 / 50 / 100 / 200 bar</li><li><i>C 300/2 (dual-stage):</i> 1 / 3 / 6 / 10 / 14 bar</li></ul></li><li><strong>Gas compatibility:</strong><ul><li>Non-corrosive gases up to purity 6.0</li><li>Gas mixtures with low corrosive content</li></ul></li><li><strong>Inlet connections:</strong><ul><li>According to DIN 477 and gas specification</li></ul></li><li><strong>Outlet connections:</strong><ul><li>Compression fittings</li><li>Hose nozzles</li></ul></li></ul><h4><span><strong>Available Configurations</strong></span></h4><h5><span><strong>Models</strong></span></h5><ul><li><strong>C 300/1 (Single-stage)</strong><br>Designed for applications with stable inlet pressure</li><li><strong>C 300/2 (Dual-stage)</strong><br>Designed for fluctuating inlet pressure with maximum outlet pressure stability</li></ul><h4><span><strong>Optional Equipment</strong></span></h4><ul><li>Shut-off valve (Type A)</li><li>Needle valve (Type B)</li><li>High-pressure side purge (Type P)</li><li>Inert gas purge (Type TP)</li><li>Purge manifold (Type EP)</li><li>Post-purge (Type DP – available only for C 300/2)</li></ul><h4><span><strong>Applications</strong></span></h4><ul><li>Analytical instrumentation (e.g., GC, LC, MS systems)</li><li>Laboratory gas supply systems</li><li>Research and development environments</li><li>High-purity gas distribution systems</li><li>Applications requiring precise pressure control and contamination-free gas delivery</li></ul>

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