Visiprep Solid Phase Extraction Vacuum Manifolds

Importance of the topic

Solid phase extraction (SPE) is a cornerstone technique in analytical chemistry for isolating, concentrating and purifying analytes from complex matrices. High-throughput SPE workflows rely on robust vacuum manifold systems to deliver precise flow control, minimize cross-contamination and reduce operator hands-on time. The Visiprep series of SPE vacuum manifolds exemplifies these requirements, offering modular solutions for environmental, pharmaceutical, food and industrial applications.

Goals and overview of the specification

This product specification describes the features, operation and accessories of 12-port and 24-port Visiprep SPE vacuum manifolds, including both standard glass basin models and Visiprep-DL disposable liner versions. Emphasis is placed on design innovations that improve vacuum regulation, sample integrity and user convenience.

Methodology and instrumentation

Visiprep manifolds operate by applying controlled vacuum to SPE tubes mounted in a glass basin. Key methodological points include:

• Individual flow control via patented screw-type vacuum bleed valves with Teflon® seals to open, close or fine-tune each channel without disturbing adjacent samples.
• Stand-alone cover with integrated legs to maintain upright position of tubes and solvent guides, preventing damage or contamination during offline handling.
• Interchangeable accessories that expand functionality for large-volume sampling, gas-drying and pump protection.

Instrumentation list:

• Visiprep 12-port and 24-port SPE Vacuum Manifolds (standard and DL disposable liner models)
• Vacuum pump trap kit to protect the vacuum source from solvent ingress
• Visidry™ drying attachment for inert gas concentration and controlled drying of SPE eluates
• Visiprep Large Volume Sampler for in-situ sampling from containers
• Optional polypropylene splash guard and sample rack adapters for vials, test tubes and volumetric flasks

Main results and discussion

Innovations highlighted in this specification include the integration of a vacuum bleed valve that ensures leak-free operation and instantaneous vacuum release, and a stand-alone cover that preserves sample orientation. The use of inert materials such as glass, Teflon® and polypropylene ensures chemical compatibility with a wide range of solvents. Disposable valve liners in the DL models virtually eliminate carry-over, enhancing method reproducibility and reducing cleaning effort.

Benefits and practical applications

Key advantages of the Visiprep SPE manifolds:

• High sample throughput: simultaneous processing of up to 24 samples accelerates routine analyses.
• Precise flow control: individual valves allow gradient elution protocols and selective stoppage.
• Contamination control: disposable liners and inert guide needles prevent sample cross-talk.
• Versatile sample compatibility: accommodates vials, test tubes and volumetric flasks across a wide volume range.
• Expandable workflow: add-on modules support gas-drying, large-volume sampling and pump protection.

Future trends and possibilities

Emerging developments in SPE manifold technology may include full automation with integrated pumps and fraction collectors, real-time vacuum monitoring and adaptive flow control via software. Miniaturized and 3D-printed manifold components could further reduce solvent consumption and enable point-of-use sample preparation in field laboratories.

Conclusion

The Visiprep SPE vacuum manifolds deliver a flexible, reliable platform for routine and high-throughput sample preparation. Their modular design, precise valve control and chemical resistance make them suitable for diverse analytical workflows, while optional accessories expand their utility for large-volume sampling, drying and pump protection.

References

No formal literature citations provided in the source document.