Thermo Scientific™ SampleManager LIMS™ and Thermo Scientific™ Chromeleon™ CDS Link

Importance of the Topic

Analytical laboratories face challenges in managing diverse data sources while ensuring data integrity, regulatory compliance and operational efficiency. Integrating laboratory information management systems (LIMS) with chromatography data systems (CDS) streamlines workflows, reduces manual tasks and supports a paperless environment.

Objectives and Overview of the Article

This technical bulletin describes the integration between Thermo Scientific™ SampleManager LIMS™ and Chromeleon™ CDS. The aim is to provide a unified informatics platform that manages sample execution, data capture, processing and reporting across multiple chromatographic and mass spectrometric instruments.

Methodology

The integration is implemented as an out-of-the-box interface within a single software platform. It leverages workflow capabilities to automate handovers between LIMS and CDS at defined decision points. Users can monitor queue status and instrument health directly from the LIMS, triggering sample runs and service notifications.

Instrumentation Used

• Thermo Scientific GC-MS/MS and LC-MS/MS systems
• Thermo Scientific Ion Chromatography (IC) and ASE-350 modules
• Third-party GC and LC modules from Agilent, Waters, PerkinElmer and Shimadzu

Main Results and Discussion

The linked system supports over 400 instrument modules from more than 15 vendors. Integration eliminates up to eight manual steps, leaving only sample loading and run initiation. Centralized data management across LC, GC, IC and MS methods improves traceability. Advanced search and data mining tools enable cross-batch and cross-instrument analysis with interactive dashboards for trend review and root cause identification.

Benefits and Practical Applications

• Enhanced data integrity and compliance through secure, validated workflows
• Reduced operating costs and manual effort via automation
• Improved instrument utilization and proactive maintenance scheduling
• Paperless laboratory environment with unified data access and reporting

Future Trends and Opportunities

Emerging developments include cloud-based LIMS/CDS deployments, expanded AI-driven analytics for predictive maintenance and process optimization, integration of IoT sensor data, and federated data sharing across global networks to support real-time decision making.

Conclusion

The integration of SampleManager LIMS with Chromeleon CDS delivers a comprehensive informatics solution that unifies control of chromatography and mass spectrometry instruments, streamlines laboratory workflows and fosters a paperless environment, driving improved efficiency, data quality and regulatory compliance.

References

No references were provided in the original document.