Supplies - GRAPHPACK

Importance of the Topic

Gas chromatography (GC) relies on precise, leak-free connections between capillary columns and inlet/detector interfaces to maintain sensitivity, reproducibility and sample integrity. Graphite-packed ferrules and modular adapters simplify column changes, reduce dead volume and prevent damage to column coatings. In industrial, environmental and pharmaceutical laboratories, robust connection technology is essential for high-throughput analysis and method reliability.

Objectives and Overview

This application note presents the GERSTEL GRAPHPACK® 2M and 3D/2 connection systems. It outlines the design principles, component range and compatibility with major GC inlets, detectors and mass spectrometers. The goal is to demonstrate how GRAPHPACK minimizes installation time, improves centering accuracy and maintains leak-free performance through temperature cycles and vacuum conditions.

Methodology and Instrumentation

The GRAPHPACK 2M system consists of a graphite-packed ferrule, a matching adapter body and a securing nut. Components are offered for column outer diameters from 0.20 mm to 0.80 mm and designed for Swagelok® ports or manufacturer-specific interfaces. Installation tools and insert kits ensure proper ferrule positioning outside the oven. The GRAPHPACK 3D/2 series features Sulfinert®-coated ferrules, connectors, screws and crosspieces for multi-column assemblies, delivering low dead volume and chemical inertness. Instrument compatibility covers Agilent, PerkinElmer, Shimadzu, Varian, Dani, Chrompack, O.I. Analytical and others.

Main Results and Discussion

• Rapid, tool-free column changes are achieved by self-centering ferrules that require minimal torque.
• Leak-free seals are maintained under thermal cycling and high vacuum without graphite migration.
• Single sealing technology across inlets, detectors and splitters reduces inventory complexity.
• GRAPHPACK 3D/2 crosspieces enable dual-column or multiplexed configurations with negligible dead volume.
Integration tests confirmed reliable performance on flame ionization, thermal conductivity, mass spectrometric and ionization detectors.

Benefits and Practical Applications

• Faster column replacement and reduced downtime in QA/QC workflows.
• Improved reproducibility from precise, self-centering seals.
• Compatibility with a wide range of GC systems using a common ferrule design.
• Enhanced inertness for trace-level analysis of sulfur, amines and oxygenates via Sulfinert coating.

Future Trends and Possibilities

As GC moves toward higher throughput and multidimensional configurations, advanced connection systems will integrate microfluidic interfaces and active temperature control. Nanocoatings may further reduce adsorption and background. Smart adapters with embedded sensors could monitor seal integrity in real time and automate maintenance scheduling. Expanding material compatibility will support new stationary phases and reactive analytes.

Conclusion

The GERSTEL GRAPHPACK 2M and 3D/2 technologies deliver rapid, reliable and inert column connections for modern GC applications. Their modular design, broad instrument compatibility and minimal dead volume enhance analytical performance and operational efficiency. By unifying sealing components across inlets, detectors and interfaces, GRAPHPACK simplifies inventory management and supports robust method development.

Reference

Gerstel GmbH & Co. KG, "GRAPHPACK® 2M and 3D/2 Connection Technology," Application Note, 2015.