Agilent MS45 Rotary Vane Pump

Brochures and specifications | 2026 | Agilent TechnologiesInstrumentation
GC/MSD, GC/MS/MS, GC/TOF, GC/HRMS, LC/MS, ICP/MS, Microscopy, Laboratory instruments
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Agilent Technologies

Summary

Agilent MS45 Rotary Vane Pump — Technical Summary


Significance of the topic


The choice and specification of a backing pump are critical for analytical platforms such as LC/MS, ICP/MS, GC/TOF/MS and electron microscopy. Reliable vacuum performance below 10 Torr with stable throughput, controllable motor speed and robust connectivity directly influence instrument uptime, analytical sensitivity, and total cost of ownership in laboratory and industrial environments. The Agilent MS45 single-stage rotary vane pump is positioned as a compact, inverter-driven solution addressing these operational needs.

Objectives and overview of the product


This data sheet documents the design intent and key performance characteristics of the Agilent MS45. The primary aims are to provide a versatile, energy-efficient single-stage rotary vane pump that:
  • delivers consistent high gas throughput below 10 Torr,
  • adapts to global mains voltages and frequencies, and
  • integrates with laboratory control systems via standard serial and network interfaces.
The MS45 targets a broad set of scientific instruments requiring reliable backing pressures, compact footprint, and simplified integration.

Used instrumentation


The document describes the Agilent MS45 pump unit and its accessories. Key elements include:
  • Model: Agilent MS45 single-stage rotary vane pump with inverter motor
  • Interfaces: RS-232, RS-485 and RJ-45 (Ethernet) for control and monitoring; compatibility with Agilent A-PLUS software
  • Mechanical connections: KF25 inlet and KF25 exhaust flanges
  • Safety and filtration accessories: built-in anti-suck-back device, exhaust filter kits, oil mist filter cap
  • Service and maintenance items: major maintenance kit, oil sight window gasket, oil level indicator, spare part kits

Methodology and key technical specifications


Performance and design parameters reported in the data sheet (high-level summary):
  • Pumping principle: single-stage rotary vane
  • Speed options (RPM): 900, 1050, 1200, 1350 (rotational frequencies: 30, 35, 40, 45 Hz)
  • Max pumping speed (nominal per ISO21360-1/2): approx. 32–45 m3/h depending on RPM
  • Ultimate pressure: < 5 × 10–2 mbar
  • Motor rating: 0.75 kW; maximum input power 1,000 VA
  • Oil capacity: 1 L (uses Agilent AVF 60 GOLD or equivalent rotary vane pump fluid)
  • Nominal input voltage: 100–240 VAC (±10%), 50/60 Hz — universal mains compatibility
  • Noise level: <58–61 dB(A) depending on speed setting
  • Physical: 440 × 306 × 271 mm; weight 35 kg
  • Operating range: ambient 12–40 °C; max altitude 4,000 m; IP20 enclosure; installation category II; pollution degree 2
  • Connections and accessories: KF25 inlet/exhaust, multiple power cable options supplied separately, control cabling options (DB9 interlock, RS232 cable)
The sheet includes two performance curves: a pumping-speed vs. pressure curve (showing typical speed falloff with increasing pressure) and a power-consumption vs. pressure curve (showing lower power demand at certain operating points, dependent on RPM). These graphs illustrate how inverter-driven speed control shifts the pump operating envelope and power requirement across the rough vacuum range.

Main results and discussion


The MS45 combines inverter motor control with a compact rotary vane design to deliver adaptable pumping capacity and energy savings. Key practical observations from the specification set:
  • Variable-speed control enables matching pump throughput to instrument gas load, improving steady-state power efficiency and reducing heat load in the lab.
  • Universal voltage/frequency compatibility simplifies global deployment without requiring different motor variants.
  • The ultimate pressure (<5×10–2 mbar) and reported nominal pumping speeds make the MS45 suitable as a backing pump for many mass spectrometers and analytical instruments operating in the rough-to-medium vacuum range.
  • Integrated anti-suck-back and standard KF25 ports reduce risk of contamination and simplify plumbing to analytical instruments.
  • Noise ratings under 61 dB(A) are consistent with bench-top laboratory use, though installation location should still consider acoustic and vibration isolation for sensitive equipment.
Practical trade-offs include the use of an oil-sealed rotary vane design, which mandates oil handling and periodic maintenance (filters, oil changes) but offers robust throughput and low capital cost compared with some oil-free alternatives.

Benefits and practical applications


Primary advantages and target uses:
  • Applications: backing pump for LC/MS, ICP/MS, GC/TOF/MS, electron microscopy roughing, vacuum lines for sample preparation, and other scientific instrumentation requiring reliable rough vacuum.
  • Energy efficiency: inverter motor reduces power draw by allowing dynamic speed adjustment to load.
  • Connectivity: RS-232/RS-485/RJ-45 interfaces enable remote monitoring, integration with instrument control software and facility automation.
  • Serviceability: standardized KF flanges and available maintenance kits simplify part replacement and upkeep.
  • Global deployment: universal input voltage and compliance with international safety and EMC standards ease cross-border installation.
Operational considerations:
  • Requires periodic oil maintenance and appropriate disposal of used oil and filters.
  • Shipped without a power cord; users must order region-appropriate power cable separately.
  • For installations at altitude or elevated ambient temperatures, review derating and ventilation needs to maintain motor and bearing life.

Future trends and potential applications


Expected developments and how MS45-type pumps fit into evolving lab needs:
  • Increased digital integration: deeper telemetry (IoT-enabled sensors, cloud analytics) and predictive maintenance using vibration, temperature and oil-condition monitoring.
  • Energy and emission targets: tighter regulation and lab sustainability programs will favor inverter-driven and demand-controlled vacuum systems to reduce energy consumption.
  • Alternative fluids and low-emission lubricants: development of synthetics or low-vapor oils to reduce contamination and environmental impact.
  • Hybrid and oil-free solutions for contamination-sensitive applications: while rotary vane pumps remain cost-effective, adoption of dry or hybrid backing pumps may grow where trace hydrocarbon background is critical.
  • Modular system integration: more compact, stackable or rack-mountable pump assemblies with standardized digital interfaces for multi-instrument labs.

Conclusion


The Agilent MS45 rotary vane pump is a pragmatic, inverter-driven backing pump designed for a broad set of analytical and scientific applications. Its combination of variable-speed control, universal electrical compatibility, standard KF flanges and digital communications makes it well-suited to modern lab workflows. The pump’s oil-sealed design requires routine maintenance but provides robust throughput and a low ultimate pressure suitable for many mass spectrometry and microscopy platforms.

References


Standards and directives cited in the data sheet (as applicable references for safety, EMC and energy performance):
  • Machinery Directive 2006/42/EC
  • EN 1012-2:1996 + A1:2010
  • EN ISO 12100:2012
  • Low Voltage Directive 2014/35/EU and IEC 61010-1 Ed. 3.1 b:2018
  • Electromagnetic Compatibility 2014/30/EU and EN 61326-1:2020 Class B; EN 61000-3-2:2019 Class A; EN 61000-3-3:2014/A2:2022 Class A; EN 61000-6-2:2020
  • Ecodesign Directive 2009/125/EC and Regulation (EU) 2019/178; EN 60034-30-1:2015
  • Performance standards referenced: ISO21360-1 and ISO21360-2 (pumping speed and performance measurement)

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