Small Molecule Metabolite Identifications in Diabetic Versus Non-Diabetic Urine Sample Groups Using Comprehensive Two-Dimensional Gas Chromatography Combined with Time-of-Flight Mass Spectrometry (GCxGC-TOFMS)Applications | 2008 | LECOInstrumentationGCxGC, GC/MSD, GC/TOFIndustriesMetabolomics, Clinical ResearchManufacturerAgilent Technologies, LECOKey wordsdiabetic, gcxgc, molecule, tofms, small, metabolite, profile, groups, fisher, disease, derivatized, metabolomic, differences, urine, chemical, dimensional, chromatof, showing, tms, state, between, non, statistical, data, sample, deconvolution, flight, normal, aid, diseased, peak, research, identify, mass, spectrometry, ratios, conducted, feature, study, chromatography, trimethylsilyl, chromatogram, ratio, mining, comparisons, otherwise, algorithms, combined, comprehensive, density
Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Plasma Samples from Lean, Fat, and Obese Rats
Utilization of GCxGC-TOFMS to Screen for PotentialMetabolite Differences in Pooled Plasma Samplesfrom Lean, Fat, and Obese RatsLECO Corporation; Saint Joseph, Michigan USAKeywords: GCxGC, Metabolomics, Biomarkers1. Introduction2. Experimental ConditionsThis GCxGC-TOFMS research presents the comparison ofpooled derivatized plasma samples from lean, fat,...
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Utilization of Comprehensive Two-Dimensional Gas Chromatography Combined with Time of Flight Mass Spectrometry (GCxGC-TOFMS) for Small Metabolite Identifications in Complex Biological Samples
®Delivering the Right ResultsUtilization of Comprehensive Two-Dimensional Gas Chromatography Combined with Time of Flight Mass Spectrometry (GCxGC-TOFMS) for Small Metabolite Identifications in Complex Biological SamplesJohn Heim and Mark Libardoni • LECO Corporation, St. Joseph, MIINTRODUCTIONEXPERIMENTALGCxGC-TOFMSSmall molecule metabolite analysis presents challenges...
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GCxGC-TOFMS Data Interpretation of Metabolic Biomarkers from Diabetic and Non-diabetic Urine Utilizing Fisher Ratios Prior to Multivariate Analysis
®Delivering the Right ResultsGCxGC-TOFMS Data Interpretation of Metabolic Biomarkers from Diabetic andNon-diabetic Urine Utilizing Fisher Ratios Prior to Multivariate AnalysisJohn R. Heim, Scott Pugh, and Mark Libardoni • LECO Corporation, St. Joseph, MichiganOVERVIEWEXPERIMENTAL METHODS®Illustrate the application of the new features...
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GCxGC-TOFMS Analysis of Mouse Plasma Extracts to Determine Metabolite Profiles From a Traumatic Brain Injury Study
GCxGC-TOFMS Analysis of Mouse Plasma Extracts to Determine Metabolite Profiles From a Traumatic Brain Injury StudyJohn Heim, Liz Humston-Fulmer, and Joe Binkley | LECO Corporation, Saint Joseph, MI USAINTRODUCTIONMETHODSComprehensive two-dimensional gas chromatography time-of-flight massspectrometry has gained recognition as a principal...
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