Chromeleon 7.3 - List of Supported Instruments

Importance of the Topic

Chromeleon 7.3 serves as a central control and data‐acquisition environment for a broad spectrum of chromatography and mass spectrometry instrumentation. Consistent instrument support ensures streamlined workflows in R&D, QA/QC, and production laboratories, reducing downtime and qualification overhead.

Objectives and Article Overview

• Provide a consolidated reference of instrument compatibility with Chromeleon 7.3.
• Detail supported manufacturers, models, firmware, interfaces, and licensing requirements.
• Identify obsolete drivers and third‐party driver sources.

Used Instrumentation

• Thermo Fisher Scientific: Dionex ASE, ICS (1000–6000 series), UltiMate 3000, Summit, Vanquish, Exactive and TSQ mass spectrometers, IC–MS, GC–MS.
• Third‐party GC/LC/IC/Detector modules: Agilent, Shimadzu, PerkinElmer, Waters, Varian/Bruker/SCION, Gilson, ISCO, Markes, ESA.
• Common interfaces: RS232, USB (1.1 & 2.0), LAN/Ethernet, analog‐digital converters (UCI, A2D).

Methodology and Compatibility Mapping

This reference compiles manufacturer‐provided firmware versions against minimum Chromeleon releases. Each entry includes:

• Required instrument license class (Thermo Fisher, 3D, GC‐MS, LC‐MS, Fraction Collection).
• Supported operating systems (Windows 8.1/10, 64 bit) and 247 controller firmware (WES7/Windows 10).
• Obsolete drivers retained for backward compatibility; third‐party drivers certified by Thermo Fisher.

Key Findings and Discussion

• Extensive native support covers hundreds of modules spanning solvent delivery, sample introduction, detectors, ovens, valves, and fraction collectors.
• MS tuning/calibration compliance extends to Exactive and TSQ platforms with on‐demand sequence integration.
• Obsolete drivers remain available but are unsupported beyond best‐effort maintenance.
• Third‐party driver manufacturers supply additional modules (e.g., HITACHI Chromaster, Knauer Azura, GAS GC).

Benefits and Practical Applications

• Single software platform reduces training burden and simplifies regulatory compliance.
• Broad instrument compatibility accelerates method development and transfer across laboratories.
• License‐based modularity allows scaling from single benchtop systems to enterprise‐wide deployments.

Future Trends and Potential Uses

• Enhanced support for emerging detectors (e.g., charged aerosol, PDD, advanced EI/CI sources).
• Cloud‐enabled data archival and AI‐driven method optimization.
• Expansion of compliance features for mass spectrometer tuning and calibration.
• Integration with laboratory automation and IoT device orchestration.

Conclusion

Chromeleon 7.3 delivers an exhaustive, up‐to‐date map of instrument support, enabling laboratories to efficiently manage diverse chromatography and mass spectrometry workflows. Ongoing enhancements and certified third‐party drivers ensure adaptability to future technological advances.

References

No bibliographic references were provided in the original text.