Clarity Control Module SHIMADZU AOC-20

Importance of the topic

The implementation of reliable autosampler control in chromatographic workflows is essential for enhancing laboratory productivity, ensuring reproducibility of injections, and reducing human error. Integrating the Shimadzu AOC-20 series autosampler with Clarity software allows seamless method execution and comprehensive data management in GC analysis.

Objectives and overview

This summary reviews the steps required to set up and operate the Shimadzu AOC-20i/s/d control module within the Clarity chromatography station. Key aims include establishing communication via RS-232, configuring software parameters, automating injection sequences, and troubleshooting common issues.

Used instrumentation

• Shimadzu AOC-20i/s/d autosampler
• DataApex Clarity chromatography software with AS Control module
• PC serial port (16550 UART compatible) or USB-to-COM adapter
• Serial cross DB9F-DB9F cable (or DB9M-DB9F if required)

Methodology and instrumentation

Installation begins by connecting the autosampler controller board to the PC using an RS-232 cross cable. The Clarity System Configuration dialog is then used to add and configure the AOC-20 control module by selecting the correct COM port, baud rate, parity, and stop bits. In the Method Setup dialog, users define injection parameters such as dwell time, rinse cycles, suction and injection speeds, and solvent selection. Control mode options allow standard or solvent-flush injections and support up to three solvent vials when enabled.

Main results and discussion

Once communication is verified, the autosampler can be fully commanded from within Clarity. Sequences are managed through the Clarity sequence table, specifying vial ranges, injection counts, and volumes. Clarity handles external start signals, synchronizes GC runs with autosampler events, and logs each injection method to chromatogram metadata. Built-in diagnostics and optional communication logging facilitate rapid troubleshooting of link failures or parameter mismatches.

Benefits and practical applications

• Automated sample injection increases throughput and consistency.
• Centralized method management within Clarity simplifies validation and audit trails.
• Flexible wash and injection protocols accommodate a variety of sample types and solvents.
• Digital communication replaces manual triggers, reducing synchronization errors with GC instruments.

Future trends and potential applications

Advancements may include USB or Ethernet interfaces for higher data rates and longer cable runs, web-based instrument monitoring, and cloud integration for remote control and data storage. Enhanced diagnostic tools and AI-driven optimization of injection parameters could further streamline workflow efficiency.

Conclusion

Integrating the Shimadzu AOC-20 autosampler into the Clarity environment offers robust and flexible control of sample injection, improving laboratory efficiency and reproducibility. Proper configuration and communication ensure seamless synchronization with GC instruments, while troubleshooting features support reliable operation in demanding analytical settings.

Reference

DataApex Ltd. Shimadzu AOC-20 Clarity Control Module, Manual Code M090/90C, February 2024