Clarity (Lite) 2.4 vs 2.3

Importance of the topic

The upgrade of chromatography data software from version 2.3 to 2.4 introduces key enhancements that streamline data integration, improve calibration accuracy, and expand instrument control options. These improvements support laboratories in meeting regulatory requirements, optimizing workflows, and ensuring reliable quantitative results.

Objectives and scope of study

This summary outlines the main differences between Clarity 2.4 (Lite) and 2.3, focusing on functional extensions in chromatogram processing, calibration, sequence management, instrument communication, report generation, and add-on modules.

Methodology and instrumentation

The study is based on a detailed comparison of release notes and user manual updates from DataApex. New software commands and dialogs were reviewed without involving additional hardware experiments. Although no specific chromatographic instruments are tested here, the software interfaces with HPLC, GC, GPC, PDA detectors, elemental analyzers, and external A/D converters.

Main results and discussion

• Protection and trial mode: Introduction of a mandatory USB or LPT dongle for version 2.4 and a 30-day full-mode evaluation option.
• Chromatogram processing: New global/local peak width and threshold tools, fast sequential browsing, automatic FFT filter, enhanced text import, and interactive tooltips.
• Calibration enhancements: Support for LOD/LOQ limits, retention (Kovats) index entries, calibration templates, and the ability to clear previous responses for refined recalibration.
• Sequence management: Per-row PostRun functions, customizable sequence templates, improved stop behavior, and faster pre-run checks.
• Instrument control: Flexible method sending modes (automatic, prompt, or disabled) for LC/GC/AS, and easy switching to GPC mode when the add-on module is installed.
• Report setup: Direct printing to PDF or email attachment, extended GLP metadata, and enhanced header customization.
• Other usability improvements: Visual relay state display, standard zoom behavior, and additional chromatogram annotations.
• Add-on modules: Updates to PDA (3D spectral) processing, elemental analysis (EA) support, Agilent 1100/6890 control via LAN, and Net-PAD Ethernet A/D converter integration.

Benefits and practical applications

The new features accelerate method development and routine analysis by reducing manual adjustments, ensuring consistent calibration, and simplifying data exchange. Enhanced report output and GLP support improve compliance and data traceability across QC, research, and industrial environments.

Future trends and possibilities

Future developments may include cloud-based data storage, integration of AI-driven peak detection, remote instrument control over secure networks, and expanded compatibility with emerging detector technologies. Continuous feedback from users will guide further automation and analytics enhancements.

Conclusion

Clarity 2.4 represents a significant step forward in chromatography data processing, offering robust integration tools, greater calibration control, and more flexible instrument communication. These upgrades support modern laboratory requirements for efficiency, accuracy, and regulatory compliance.

References

DataApex Ltd. Clarity 2.4 vs 2.3 Release Notes, Code/Rev. M047/24F, January 2006.