Metrohm MIRA Cal M Tutorial

Significance of the Topic

The MIRA Cal M mobile application enables streamlined, on-site Raman spectroscopy analysis, enhancing field-based chemical identification, quality control and safety assessments. By leveraging Bluetooth connectivity with the MIRA XTR DS / MIRA DS analyzer, the platform supports rapid decision-making in pharmaceutical, environmental and security contexts.

Objectives and Overview

This tutorial introduces key workflows in MIRA Cal M version 2.XX+ for Android devices (8.0–11.0) paired with MIRA XTR DS / MIRA DS firmware 8.0.1.136+. The guide covers installation, instrument calibration, sample acquisition, metadata management, library creation, data export, and diagnostic logging.

Methodology and Instrumentation

Ultramobile Raman analysis is achieved by:

• MIRA Cal M Android app (8.0105.8023EN / 2021-09-15)
• Metrohm Instant Raman Analyzer MIRA XTR DS or MIRA DS
• Bluetooth® wireless connection (PIN 9999)
• Calibration standard for wavelength and intensity calibration
• Optional Autofocus Stand‐off attachment with integrated aiming laser
• HazMasterG3® compatibility for hazard data fusion

Main Features and Discussion

Key capabilities include:

• Instrument Setup: Bluetooth pairing, automatic or prompted calibration, and system suitability tests.
• Acquisition Modes: Continuous scans, multi-scan averaging, identification matching (threshold & max matches), mixture matching, and full vs. partial download options.
• Sample Handling: Real-time metadata capture (geolocation, photos, custom names), filtering, overlay of multiple spectra, and reprocessing with local or device libraries.
• Library Management: Creation, import/export of user and licensed libraries, assignment of CAS numbers, hazard levels and sample types.
• Data Export: Flexible reporting formats (PDF, CSV, SPC), external storage, email, and direct export into HazMasterG3 sensor import folder.
• Diagnostics: Device log export for remote troubleshooting and developer support.

Benefits and Practical Applications

• Field-deployable Raman analysis requiring minimal user training.
• Comprehensive metadata and reporting for regulatory compliance.
• Seamless integration with chemical safety software (HazMasterG3).
• Customizable libraries to support in-house compound databases.
• Efficient workflows for QA/QC in pharmaceutical, forensic, environmental and industrial settings.

Future Trends and Potential Applications

Ongoing developments may include cloud-based library synchronization, AI-driven spectral deconvolution, expanded compatibility with other spectrometers, enhanced user-role management, IoT connectivity for remote monitoring, and predictive analytics for automated hazard warnings.

Conclusion

MIRA Cal M delivers a robust, user-friendly platform for portable Raman spectroscopy, combining reliable calibration, versatile acquisition modes, extensive sample management and flexible data export. It addresses modern demands for rapid, accurate, and traceable chemical identification in diverse field applications.

Reference

Metrohm Raman. MIRA Cal M Tutorial. Document 8.0105.8023EN, September 15, 2021.