Site Requirements - Biotage Extrahera LV-200

Importance of the topic

The successful deployment of automated solid-phase extraction systems in analytical laboratories depends on rigorous site preparation. Proper installation avoids safety hazards, ensures compliance with operational specifications and maximizes the instrument’s uptime and analytical reliability.

Objectives and Study Overview

This document outlines the essential laboratory requirements for installing the Biotage Extrahera LV-200. It aims to guide facility managers and end users through space planning, environmental controls, utility connections and verification steps needed for a seamless setup.

Methodology and Instrumentation

This summary is based on the official site requirements manual for the Biotage Extrahera LV-200. The core instrument under discussion is the Biotage Extrahera LV-200 automated extraction platform. Site qualification follows a checklist approach covering ventilation, load-bearing, utilities and safety systems.

Used Instrumentation

• Biotage Extrahera LV-200 automated solid-phase extraction system

Main Results and Discussion

The key installation parameters are:

• Ventilation: Dedicated fume hood or equivalent exhaust achieving ≥6 m³/min; optional duct adapter (159 mm OD, 152.7 mm ID) for benchtop installations.
• Weight and Footprint: Package weight 125 kg; unpacked instrument 80 kg; bench or hood must support this load. Dimensions with touchscreen 860×570×790 mm; without touchscreen 610×510×790 mm.
• Environmental Conditions: Ambient temperature 18–32 °C, humidity 10–90 % RH, low dust and particle emission.
• Electrical Supply: 100–240 VAC, 50/60 Hz, 300 VA, properly grounded outlet.
• Gas Supply: Filtered air and nitrogen per ISO 8573-1 class 1-x-1. Air: 5 L/min at 6 bar; N₂: 1 L/min processing, 70 L/min drying at 6 bar; tubing 6 mm OD, 4 mm ID.
• Vacuum Supply: <500 mbar, ≥8.3 L/min, tubing 6 mm OD, 4 mm ID.
• Fire Protection: External safeguards per local regulations for unattended equipment.

The manual also specifies that two pressure regulators and adapters are provided. A system checkout using a high-precision balance and deionized water verifies proper installation.

Benefits and Practical Applications of the Method

Adhering to these site requirements ensures:

• Safe operation without gas or particle exposure risks.
• Optimal extraction performance and reproducibility.
• Reduced downtime and maintenance by preventing contamination.

Future Trends and Potential Applications

Advances in lab automation will drive integration of SPE platforms with LC-MS and other online systems. Future developments may focus on compact, self-ventilated designs, modular gas management and enhanced remote monitoring for quality assurance.

Conclusion

Meeting the ventilation, structural, environmental and utility specifications is vital for a reliable installation of the Biotage Extrahera LV-200. Careful site preparation accelerates commissioning, ensures user safety and supports high-quality analytical workflows.

Reference

• Biotage. Site Requirements: Extrahera LV-200. Literature Number UI472, 2021.