Applications - page 1

High-sensitive multi-attribute analysis of ADCs under native conditions by using an online multiple heart-cut 2D-LC-HRAM mass spectrometry system

Posters
| 2025 | Thermo Fisher Scientific (HPLC Symposium)
2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC
Instrumentation
2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Green ion pair and HFIP free method for ASO RNA analysis with GLP compliant automated data handling

Posters
| 2025 | Thermo Fisher Scientific (HPLC Symposium)
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Detailed study into ASO impurity analysis, lessons learned, and myths dispelled while moving to compliant platform methods

Posters
| 2025 | Thermo Fisher Scientific (HPLC Symposium)
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Interference of adjacent ion signals in CDMS: the effect on charge accuracy and potential correction algorithms

Posters
| 2025 | Thermo Fisher Scientific (ASMS)
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS, Software
Instrumentation
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS, Software
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics

Enhanced HCP quantitation LC-MS/MS workflow solution using a MS sample prep method

Posters
| 2025 | Thermo Fisher Scientific (ASMS)
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS, Sample Preparation
Instrumentation
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS, Sample Preparation
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Leveraging advanced mass spectrometry technology with Orbitrap Astral Zoom MS for in depth immunopeptidome profiling

Posters
| 2025 | Thermo Fisher Scientific (ASMS)
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS
Instrumentation
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics

High-sensitivity Host Cell Protein (HCP) analysis on a new Orbitrap Excedion Pro BioPharma hybrid mass spectrometer with optimized sample preparation

Posters
| 2025 | Thermo Fisher Scientific (ASMS)
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS, Sample Preparation
Instrumentation
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS, Sample Preparation
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Evaluation of a modified Orbitrap Astral Mass Spectrometer for label-free quantitation of proteomic samples

Posters
| 2025 | Thermo Fisher Scientific (ASMS)
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics

Enhanced resolution with multi-pass mode on the Orbitrap Astral Zoom mass spectrometer

Posters
| 2025 | Thermo Fisher Scientific (ASMS)
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS
Instrumentation
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics

Rapid monitoring of mAb aggregates during the purification process development of therapeutic mAbs using a modified Orbitrap hybrid MS

Posters
| 2025 | Thermo Fisher Scientific (ASMS)
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS, Software
Instrumentation
LC/HRMS, LC/Orbitrap, LC/MS/MS, LC/MS, Software
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Other projects
LCMS
ICPMS
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