Mass Spectrometry Symposium 2025
The Mass Spectrometry Symposium provides an interactive forum with a focus on mass spectrometry (MS) in the biotechnology industry to share experiences, insights, and novel developments between industry, academia, and regulatory agencies worldwide. The Symposium will communicate best practices and innovative approaches for mass spectrometry applications in biopharma.
All members of the biopharmaceutical field, including industry, regulatory, and academic professionals, are encouraged to attend the Mass Spec Symposium.
Mass Spec will bring together industry, regulatory ,and academic professionals to discuss MAM for Product & Process Characterization & Quality Control, Mass Spectrometry in Cell & Gene Therapy, Mass Spectrometry in Higher Order Structure, Molecular Design, Developability, and Biotransformation, MS Trends in Regulatory, Research, Review, and Standard, Multispecifics and ADCs Characterization, Multi-Omics in Process Development, and New Technologies, Approaches, and Methods.
Registration
Registration fees
REGULAR BY SEPTEMBER 10, 2025
Join us for the Symposium at the Hilton Orange County/Costa Mesa in Costa Mesa, Southern California, USA. Symposium registration includes all sessions on September 24-26, 2025, breakfast, lunch, coffee breaks, networking, technical seminars, access to the Exhibit and Poster Hall, and Networking Reception. Along with all aspects of the in-person experience, you have access to the Symposium website, meeting mobile app, and Oxford online schedule which features the final program, abstracts, and presenters' slides (when made available). Registration for the Short Course on September 23, 2025 is an additional cost not included in the Mass Spec Symposium registration fee. Additional information on the Short Course will be available soon. Register for in-person attendance by September 10, 2025.
- Industry: $2,350.00
- Academic/Government: $999.00
- Independent Consultant***: $999.00
- Health Authority: $800.00
- Health Authority One Day Rate***: $350.00
- Student: $475.00
- Short Course: $699.00
Virtual by SEPTEMBER 18, 2025 at 5 PM PST
Join us virtually from anywhere in the world for the Symposium. Virtual registration includes a live-streaming broadcast of the Mass Spec Symposium on September 24-26, 2025, including talks, panel discussions, and technical seminars. Along with all aspects of the live streaming broadcast, you also have access to the Symposium website, meeting mobile app, and Oxford online schedule which features the final program, abstracts, and presenters' slides (when available). Register for virtual attendance by September 18, 2025.
- Industry: $899.00
- Academic/Government: $499.00
- Independent Consultant***: $499.00
- Health Authority: $499.00
- Student: $399.00
ONSITE**
- Industry: $2,550.00
- Academic/Government: $1,199.00
- Independent Consultant***: $1,199.00
- Health Authority: $1,000.00
- Health Authority One Day Rate***: $550.00
- Student: $475.00
- Short Course: $899.00
Note: Virtual registration does not include access to the roundtable discussions, poster sessions, or the pre-conference short course. Roundtables, poster sessions, and the pre-conference short course are only available in-person.
*All registration fees are in US dollars.
**Onsite registration is subject to availability and is not guaranteed.
***Please contact [email protected] to receive the independent consultant rate or health authority one day rate.
Abstract Submission
Submit your Abstract HERE
Important Presenter Deadlines
Wednesday, June 25, 2025: Oral Abstract Submissions - DEADLINE EXTENDED TO JULY 4, 2025
- Deadline to submit oral abstracts for consideration.
Thursday, July 24, 2025: Invited Abstract Submissions
- Abstract submission deadline for invited oral presenters, panelists, and roundtable facilitators. The submission includes abstract, speaker permissions, speaker bio, and headshot.
Thursday, August 21, 2025: Poster Abstract Submissions
- Deadline to submit poster abstracts for consideration.
Monday, September 1, 2025: Hotel Registration
- Last day to reserve your hotel accommodations at the host hotel at the special group rate. Please note: program registration does not include lodging, so be sure to book your hotel room before the deadline.
Topics include:
- MAM for Product & Process Characterization & Quality Control
- Mass Spectrometry in Cell & Gene Therapy
- Mass Spectrometry in Higher Order Structure
- MS Applications for Research and Early Stage Development
- MS Trends in Regulatory, Research, Review, and Standard
- Multispecifics and ADCs Characterization
- Multi-Omics in Process Development
- New Technologies, Approaches, and Methods
Oral and Poster Presentation Guidelines
Poster Presentation Format
Poster authors will have one (1) landscape, 4’ x 8’ poster board to mount their posters on for viewing. The board has a frame (edges) of approximately 1.5” per side. The usable surface area of each poster is 7’ 7” wide by 3’ 9” high. Presenters will use ONE SIDE of the poster board. Presenters should plan for a maximum poster size of 91” wide by 45” high (231 cm x 114 cm). Each board will have the presenter’s poster number on it (which will be provided ahead of time), and pushpins will be available for use.
Oral Presentation Format
For oral presenters, the chairs of your session will confirm the allotted length of time for your talk as well as the order you will speak in.
All presentations should be saved as a PowerPoint file (.ppt, .pptx) in widescreen or 16:9 dimension. If your PowerPoint application defaults to 4:3 dimension, you can modify this by clicking “Design” from the top menu bar, select “Slide Size” from the Customizations section, and select “Widescreen 16:9”.
Presentations that grant permission to be shared should also be saved as a PDF and both files uploaded to the online abstract portal by the September 17, 2025 deadline. Slides submitted after this deadline are not guaranteed to be included in the final program. If you make updates to your slides after September 17, 2025, please be prepared to bring your updated file on a USB and coordinate with the audio-visual technician to load your presentation on the computer at the podium prior to your session. Speakers not allowed to use USB drives should bring their laptop and the appropriate cords to connect at the podium.
When giving your presentation, we ask that you consider optimizing your slides for all attendees by incorporating the following elements:
- Avoid using small print on presentations that can’t be seen from a distance. Use a minimal slide typeface of 24 point / legible fonts (no cursive or block letters).
- Avoid using more than 3 colors and types of fonts. White or yellow lettering on a blue background is attractive and easy to read. Avoid red and green text. Be considerate of those that are color blind.
- Avoid using more than 3 styles of slide transitions or animations.
- Activate captions on any video used in the presentation.
- Verbally describe visual materials (e.g., slides, charts, etc.).
Short course: Fundamentals and Applications of Mass Spectrometry
Tuesday, September 23, 2025
- Session I: Fundamentals of Mass Spectrometry in the Analysis of Protein Therapeutics
- Session II: Applications of Mass Spectrometry to Characterize Biotherapeutics
Instructors
- Chris Chumsae, Bristol-Myers Squibb Company
- Andrew Mahan, Johnson & Johnson
- Rich Rogers, Umoja Biopharma
The Short Course Session I and Session II will take place on Tuesday, September 23, 2025 at the Hilton Orange County/Costa Mesa and will be offered in-person only.
Register for Short course by September 10, 2025.
Note: Registration for the short course is an additional cost not included in the conference registration fee. For additional information on pricing, view Registration Fees.
08:30 – 12:00 Fundamentals of Mass Spectrometry in the Analysis of Protein Therapeutics
- Instructor: Chris Chumsae, Bristol-Myers Squibb Company
This introductory course will provide an overview of the fundamentals of Mass Spectrometry, including the history of Mass Spectrometry, terminology, data interpretation and sample handling. We will include a discussion on modes of operation (parent versus fragment ion analysis), components of a current MS system, and selected applications of Mass Spec as it applies to protein analysis in the biotechnology industry. A discussion on software (basic interpretation and operation) will be presented along with a hardware discussion (strengths for various applications). A limited discussion on small molecule analysis will be presented.
13:00 – 16:30 Applications of Mass Spectrometry to Characterize Protein Therapeutics
Instructors:
- Andrew Mahan, Johnson & Johnson
- Rich Rogers, Umoja Biopharma
The afternoon section will focus on practical industrial uses of Mass Spectrometry in the analysis of protein therapeutics as well as in Cell and Gene Therapy. The specific topics will be Intact Mass Analysis, Structural MS, Host Cell Protein ID and Peptide Mapping and Multi-Attribute Method and protein post translational modifications: detection and quantitation. The discussions will be driven by industry leaders. Two interactive segments will cover live data analysis demos of both Intact and Reduced Mass Analysis as well as Peptide Mapping Data Analysis in variety of vendors software products.
This course will review the role MS has in newer therapeutic modalities such as multi-specific, antibody-drug conjugates, cell and gene therapy (AAV, oligonucleotides). Additionally, there will be sections covering mass spec techniques which evaluate protein structure such as hydroxy radical foot-printing, cross-linking, hydrogen-deuterium exchange, top down and middle down methods and ion mobility. The increasing use of Native MS in the analysis if mis-paired Multispecifics as well as investigation of non-covalent interaction will be covered. The 2nd part of the afternoon session focuses on Multi-Attribute Method (MAM), MS in QC, PTM quantitation as well as Sequence Variant Analysis and the role of MS in Cell Line Selection.
Scientific Program
The 2025 Mass Spectrometry (Mass Spec) Symposium will bring together industry, academia, and regulatory agencies from around the world to discuss best practices and innovative approaches for mass spectrometry applications in the discovery, development, and commercialization of biopharmaceuticals. The three-day program features speaker presentations, panel discussions, and poster sessions that give you the opportunity to engage with fellow attendees in meaningful discussions on the latest practices and challenges for mass spectrometry applications in biopharmaceuticals. We look forward to an informative Symposium and hope to see you there. Be ready to network, collaborate, and expand your knowledge.
Mass Spectrometry Symposium 2025: Keynote speakers
Venue
Hilton Orange County/Costa Mesa
- 3050 Bristol St.
- Costa Mesa, California, USA 92626
- Telephone: (714) 540-7000
Join us at the Hilton Orange County/Costa Mesa in Costa Mesa, Southern California, USA for Mass Spec Symposium 2025!
Hilton Orange County/Costa Mesa is the largest hotel in Costa Mesa and is located in the heart of South Coast Metro, Orange County's business district. Enjoy the proximity to the South Coast Plaza Stores, Orange County's premier shopping and dining destination - only 0.2 miles. Experience the spectacular 48,000 sq. ft. of event space - breakout rooms, boardrooms, and ballrooms. Hilton Orange County hotel also features an on-site restaurant, outdoor pool, complimentary fitness and business centers, and beautiful guest rooms.
Reservations
A room block is reserved for Symposium delegates at the special group rate of $185 USD for a *single or double room (plus 11.37% occupancy tax). The deadline to reserve your accommodations will close September 1, 2025. The Hilton Orange County/Costa Mesa requires a credit card to guarantee your reservation. In the event of a cancellation, the hotel requires 72 hours’ notice to receive a full refund.
After September 1, 2025, reservations will be accepted on a space and rate availability basis. We recommend that attendees book their hotel accommodations well before the deadline to secure this rate.
NOTE: Check-in time is 4:00 PM and check-out time is 11:00 AM.
