ASMS: 36th Fall Workshop

36th Fall Workshop: Fundamentals of Instrumentation for Mass Spectrometry

The workshop will focus on fundamentals related to transport, analysis, and detection of ions in MS experiments. The workshop will include topics related to the manipulation of ions during tandem MS experiments. The workshop will include the transport of ions at intermediate pressures and the integration of ion mobility into hybrid instruments.

This is not an introductory level workshop, attendees are expected to understand the basics of ionization mechanisms, dissociation mechanisms, and interpretation and application of ion mobility. Attendees not familiar with these topics are encouraged to watch educational videos in the Fundamentals category on the ASMS website.

At the conclusion of this workshop, participants will be able to:

• Describe the principles of the primary technologies used to transport, analyze, and detect ions in MS experiments.
• Summarize the figures of merit for those technologies.
• Compare the utility of different technologies for specific applications.

• ASMS profile and content on LabRulezGCMS

• ASMS profile and content on LabRulezLCMS

• ASMS profile and content on LabRulezICPMS

Registration

Registration will open in July 2025. 

The ASMS 36th Fall Workshop is an IN-PERSON event. 

Registration Fees 

• $400, ASMS Members (Regular and Emeritus)
• $600, Non-Members
• $175, Students*
  * Must be a full-time student in a degree program.

Offsite Fee $200 is required for attendees that are not local and choose not to lodge at the Arctic Club Hotel.

Registration Cancellation Policy

Written notification of registration cancellations received on or before October 15 will be refunded less a $50 cancellation fee.

Applying for a Travel Stipend for Students or Post-docs?

Will open on April 1
Travel stipend recipients will receive a free registration to the Fall Workshop and a travel stipend of up to $750.  

Eligibility & Requirements

• Applicants must be a full-time graduate student or post-doc within two years of first appointment.
• Applicant must not have received Winter, Fall Workshop, Asilomar Conference nor Annual Conference Graduate Student travel award within of the Fall Workshop.
• Limit of one applicant per research group (student or post-doc).
• Letter of recommendation from advisor. Applicant may upload in the online application or advisor may email directly to [email protected]. Letter must be received by the application deadline.
• 250-word max applicant statement.
• ASMS membership. Preference may be given to students and postdocs that are members of ASMS. 

Preliminary Program

Monday, November 3 , 2025

8:30 - 9:00 am Overview and Figures of Merit

9:10 - 9:40 am Detecting Charges and Digitizing Signals

9:50 - 10:20 am Vacuum Systems and Pressure Differentials

10:30 - 11:00 am Ion Motion in the Free-Molecular Regime and Basics of Time of Flight

11:10 - 11:40 am Electrodynamic Fields, Mathieu Stability Diagrams, and Ion Motion at Intermediate Pressures

12:00 - 1:00 pm Lunch (provided by ASMS)

1:00 - 1:30 pm Ion Guides, Drift Tubes, and Ion Funnels

1:40 - 2:10 pm Quadrupole Mass Filters and Tandem Quadrupoles

2:20 - 3:00 pm Demos (Part 1 of 2)

• Electrodynamic ion traps
• Ion trap with rod electrodes
• Simulation of ion separation by mass-to-charge
• Deconstructed instrument to see all components
• SIMION models of analyzers

3:00 - 3:30 pm Quadrupole and Linear Ion Traps

3:40 - 4:40 pm Special Considerations for Mass Spectrometry Instrumentation -  short discussions related to selection of instrumentation for selected applications.

• Instrumentation for Targeted and Clinical Analysis
• Instrumentation for Harsh Environments
• TBD

5:00 - 6:00 pm Mixer Reception

Tuesday, November 4, 2025

8:30 - 9:00 am Advanced Concepts in Time-of-Flight - phase space, energy focusing, orthogonal acceleration, and multi-reflectron analyzers

9:10 - 9:40 am FT-ICR

9:50 - 10:20 am Orbitrap

10:30 - 11:00 am Charge Detection Mass Spectrometry

11:10 - 11:40 am Panel Figures of Merit and Comparing Mass Analyzers

11:40 - 1:00 pm Lunch (provided by ASMS)

1:00 - 1:20 pm Time Scales and Impacts on Experiments

1:30 - 2:00 pm Hybrid Mass Analyzers

• Quadrupole Time-of-Flight
• Ion Mobility Time-of-Flight
• Hybrid Orbitrap

2:10 - 2:50 pm Demos (Part 2 of 2)

• Electrodynamic ion traps
• Ion trap with rod electrodes
• Simulation of ion separation by mass-to-charge
• Deconstructed instrument to see all components
• SIMION models of analyzers

3:00 - 4:00 pm Special Considerations for Mass Spectrometry Instrumentation - short discussions related to selection of instrumentation for selected applications

• Instrumentation for Quantitation of Large Numbers of Analytes
• Instrumentation for Imaging
• Instrumentation for Shared-Use Facilities

4:10 - 4:50 pm Breakout Discussions

5:00 - 5:30 pm Panel Discussion on the Future of Instrumentation for MS

Lodging & Travel

HOTEL - ARCTIC CLUB HOTEL
The Fall Workshop venue is the Arctic Club Hotel, 700 3rd Ave, Seattle, WA 98104.

Guest rooms at the Arctic Club Hotel will be available at a nightly rate of $187 plus tax.

Travel Visa & Invitation Letter

If you reside outside the USA and plan to attend an ASMS event, please be aware of the U.S. passport and visa policies for citizens and visitors. The following information is provided in good faith. It is the attendee's responsibility to verify the information and suggestions below as it applies to his/her visa scenario.

Please look for the section entitled "Supplemental Information for Visa Application Including Letter of Invitation from ASMS" for more detailed information.