From Supramolecular Chemistry Towards Adaptive Chemistry

Our faculty hosts a lecture by Nobelist Prof. J. M. Lehn

We cordially invite you to the lecture "From Supramolecular Chemistry Towards Adaptive Chemistry" by the 1987 Nobel Prize laureate in Chemistry, Prof. J.M. Lehn from the University of Strasbourg. The lecture will take place on Wednesday 26 June 2024 at 10:30 in the Large Geological Lecture Hall at Albertov Campus. Prof. J.M. Lehn will also participate in the meeting of the three Nobel Prize winners under the title Sound of Science at the Estates Theatre on Friday 28 June 2024. More information can be found below.

Faculty of Science, Charles University: prof. J.M Lehn, University Strasbourg: "From Supramolecular Chemistry Towards Adaptive Chemistry."

WHEN: Wednesday, June 26th, 2024, from 10:30 a.m.

WHERE: Lecture Hall, Albertov 6, Prague 2

Abstract:

Supramolecular chemistry is intrinsically a dynamic chemistry in view of the lability of the interactions connecting the molecular components of a supramolecular species and the resulting ability to exchange components. The same holds for molecular chemistry when the molecular entity contains covalent bonds that may form and break reversibly. These features allow for a continuous change in constitution by reorganization and exchange of building blocks and define a Constitutional Dynamic Chemistry (CDC) covering both the molecular and supramolecular levels.

CDC takes advantage of dynamic diversity to allow variation and selection and operates on dynamic constitutional diversity in response to either internal or external factors to achieve adaptation.

It generates networks of dynamically interconverting constituents, constitutional dynamic networks, that may respond to perturbations by physical stimuli or to chemical effectors. Of special interest is the case where the driving force is an increase in order.

The implementation of these concepts points to the emergence of adaptive and evolutive chemistry, towards systems of increasing complexity.