CEEPC/IPM/CMSC 2022

From September 29 – October 1, 2022 in Prague at the National Library of Technology.

Registration and abstract submission deadlines are August 29.

Conference is co-organized together with the Proteomic section of CSBMB as an international meeting in English language.

The invitation to give plenary lecture was accepted by:

• Karl Mechtler (Research Institute of Molecular Pathology, Vienna)
• Carlos Cordeiro (Universidade de Lisboa)
• Berndt Wollscheid (ETH Zurich).

The 16th Central and Eastern European Proteomic Conference is organized in cooperation with EuPA.

The best student presentations will be selected at the conference. EuPA will support winning authors to attend the 17th Annual Congress of the European Proteomics Association in 2023 (EuPA 2023). All MSc and PhD students with a poster or oral presentation are eligible for the EuPA Travel Grant and will be contacted by the organizers via email after the acceptation of their abstracts.

To register, please fill the registration form. Thanks to support of the sponsors, the conference is free of registration fee for the members of CzechMS and ČSBMB. The conference registration fee for nonmembers is EUR 100 (EUR 50 for students).

Conference abstract can be submitted after the registration is completed (and registration email confirmed). Talks (20 minutes), student short talks and posters are offered as conference contribution options. The best student short talk will be awarded a conference prize.

The Zdenek Herman Prize (awarded by Resonance Foundation) and Josef Chmelik Award (awarded by Proteomics section) will be presented during the conference.

Sponsors

• Bruker Daltonics
• Amedis
• Merck
• Beckman coulter
• Pragolab
• Waters Corporation

ČSHS: Sponsors: CEEPC/IPM/CMSC 2022

Program CEEPC/IPM/CMSC 2022

Thursday September 29, 2022

8:30 - 10:00 Registration

10:00 - 10:10 Opening of the 16th CEEPC, 8th IPM and 10th CMSC

10:10 - 11:00 Plenary lecture I: New insights through Single-Cell Proteomics (Chairperson: Petr Novák)

• Karl Mechtler

11:00 - 11:20 Coffee break

11:20 - 13:00 Session I - Method Development

• Chairperson: Katarina Davalieva

11:20 - 11:40 Identification of potential cell-surface targets and druggable enzymes in human pheochromocytoma and paraganglioma using classical and membrane-targeting proteomic approaches

• Ondřej Vít

11:40 - 12:00 Global SEC-PCP-SILAC mapping reveals protein complexes mediating NF-κB activation in breast cancer

• Petr Lapčík

12:00 - 12:20 Determination of changes in the milk proteome in production and storage of kefir using mass spectrometry-based omics approaches

• Haci Mehmet Kayili

12:20 - 12:40 Non-Immunoaffinity Extraction of Intact Proteins from Biological Fluids and Their Analysis by Liquid Chromatography – Triple Quadrupole Mass Spectrometry

• Katarína Maráková

12:40 - 13:00 Advancing Cyclic Ion Mobility Mass Spectrometry Methods for Studying Biomolecules: Towards the Conformational Dynamics of Mega Dalton Protein Aggregates

• Adam Pruška

13:00 - 15:30 Lunch + Poster session I (Odd-numbered posters)

15:30 - 16:30 Company Workshop – Bruker Daltonics

The latest proteomics development at Bruker

• Gary Kruppa

Clinical (phospho)proteomics with TIMS and PASEF

• Florian Meier

16:30 - 16:50 Coffee break

16:50 - 17:30 Short Talks

• Chairperson: Petr Man

Detection of C. difficile Toxin B by biomolecule-modified chips and mass spectrometry

• Josef Dvořák

Optimized HDX-MS workflow for antibody structure monitoring by HDX-MS

• Zuzana Kalaninová

RPLC-UV and HILIC-UV characterisation of on-site produced Ramucirumab-DTPA immunoconjugate

• Denis Naplekov

Collision energy setting in proteomics and glycoproteomics: From individual species to a practical perspective

• Agnes Revesz

Novel circulating biomarkers of biventricular heart failure

• Matěj Běhounek

Comprehensive metabolomic and lipidomic study of tauopathy and Alzheimer's disease patients

• Dana Dobešová

Overlooked oligomerization process in Azurin, a model metalloprotein

• Roman Tuzhilkin

17:30 - 18:00 Josef Chmelik Award

18:00 - 19:30 Guided tour to the conference dinner

19:30 - 23:00 Conference dinner and sightseeing boat trip

Friday September 30, 2022

8:50 - 9:40 Plenary lecture II: An FT-ICR-MS metabolomic journey (Chairperson: Michael Volný)

• Carlos Cordeiro

9:40 - 11:20 Session II - Novel Instrumentation and approaches

• Chairperson: Lászlo Drahos

9:40 - 10:00 In a flash of light: Native mass spectrometry for single particle imaging with X ray free electron lasers

• Alan Kádek

10:00 - 10:20 Qualitative and quantitative advancements of QTOF performance: the SCIEX ZenoTOF 7600 system

• Volker Kruft

10:20 - 10:40 Synergistic success of proteo-genomics in profiling human tear fluid for disease biomarkers using a novel high sensitivity Immunoassay

• Suresh Jivan Gadher

10:40 - 11:00 Back to Basics with Antibodies

• Stanislav Kukla

11:00 - 11:20 Two-dimensional mass spectrometry for top-down analysis and structural characterization of proteins

• Maria van Agthoven

11:20 - 11:40 Coffee break

11:40 - 13:00 Session Session III - MS and SW tools

• Chairperson: Eva Csosz

11:40 - 12:00 Rapid ion mobility-resolved phosphoproteomics with dia-PASEF

• Florian Meier

12:00 - 12:20 Prediction of Intact N-Glycopeptide Retention Time Windows in Hydrophilic Interaction Liquid Chromatography

• Tomáš Ječmen

12:20 - 12:40 Quantification of small molecules in liquid chromatography/mass spectrometry datasets by CycloBranch

• Jiří Novák

12:40 - 13:00 Mass spectrometric analysis of intact proteins: the dark side of deconvolution

• Lászlo Drahos

13:00 - 15:30 Lunch + Poster session II (Even-numbered posters)

15:30 - 17:30 Session IV - Applications in Biomedicine 1

• Chairperson: Maria van Agthoven

15:30 - 15:50 Identification of potential biomarkers for azoospermia by human testis proteomic analysis

• Katarina Davalieva

15:50 - 16:10 Proteotype classification of renal cell carcinoma for prognosis and therapy response

• Pavel Bouchal

16:10 - 16:30 Stability Study of Triacetylfusarinine C and Gliotoxin in bodily fluids

• Jiří Houšť

16:30 - 16:50 MALDI-TOF mass spectrometry: A powerful method for blood meal identification in insect vectors

• Petr Halada

16:50 - 17:10 Characterization of glycosphingolipids in iPSC-derived cerebral organoids and its application in neurodegenerative disorders

• Durga Jha

17:10 - 17:30 Redox resetting by modulation of redox sensor Kelch-like ECH-associated protein 1 restores leukemic cells sensitivity to Azacytidine

• Kristýna Pimková

17:30 - 18:10 Zdeněk Herman Award presented by Resonance Foundation and presentation of the winning thesis

18:10 - 18:30 Coffee break

18:30 - 19:00 General assembly of the CSMS

Saturday October 1, 2022

8:50 - 10:50 Session V - Applications in Biomedicine 2

• Chairperson: Haci Mehmet Kayili

8:50-9:10 Proteomic Analysis of Hepatitis B Virus

• Martin Hubálek

9:10-9:30 The single amino acid substitutions in Mason-Pfizer Monkey Virus matrix protein modulate its proteolytic cleavage rate

• Jakub Sýs

9:30-9:50 Cardiac alarmins as residual risk markers of atherosclerosis under lipid-lowering therapy

• Viorel-Iulian Suica

9:50-10:10 Cervical mucus – a non-invasive uterine biomarker source?

• Tomáš Oždian

10:10-10:30 High-Throughput µLC-MS/MS Lipidomics of 3D In Vitro Disease Models to Investigate Lipid Dysregulation

• Darshak Gadara

10:30-10:50 Multi-omics network analysis in atherosclerosis reveals mechanisms driving the progression towords complicated lesion

• Eva Csosz

10:50 - 11:10 Coffee break

11:10 - 12:00 Plenary lecture III: Light-mediated discovery of surfaceome nanoscale organization and inter-cellular receptor interaction networks (Chairperson: Pavel Bouchal)

• Bernd Wollscheid

12:00 - 12:20 Poster prize, Closing remarks

12:20 - 13:30 Lunch