The Agilent 7890A Gas Chromatograph (GC) and 5975C Gas Chromatograph-Mass Selective Detector (GC/MSD) systems represent the cutting edge of gas chromatography technology.
Both systems combine robust hardware with advanced software, enabling laboratories to achieve exceptional sensitivity, reliability, and efficiency. Designed for diverse applications, these instruments are suited for trace analysis, complex sample matrices, and high-throughput environments. The integration of features like electronic pneumatic control (EPC), Capillary Flow Technology (CFT), and Retention Time Locking (RTL) ensures reproducible and precise results, while compatibility with advanced autosamplers, such as the PAL system, enhances operational productivity.
The Agilent 5975C GC/MSD further extends capabilities with its high-sensitivity triple-axis detector and inert electron ionization source, enabling detailed qualitative and quantitative analyses for routine and complex samples. Together, the 7890A GC and 5975C GC/MSD systems provide a comprehensive analytical solution, optimized for efficiency, reliability, and advanced performance.
The addition of the PAL autosampler further enhances its efficiency by automating sample handling with precision and reliability.
Configuration 7890A/5975C with PAL Autosampler
Split/Splitless Inlet
- Compatibility: Suitable for capillary columns ranging from 50 µm to 530 µm inner diameter.
- Modes: Operates in split mode for high-concentration samples (split ratios up to 7,500:1) or splitless mode for trace analysis.
- Pressure Control:
- Standard: 0–100 psig for columns ≤ 0.200 mm diameter.
- Maximum Temperature: 400 °C.
- Features:
- Pressure-pulsed splitless mode for enhanced sample transfer efficiency.
- Integrated gas saver mode to minimize carrier gas consumption.
- Turn-top design for quick and tool-free injector liner changes.
PAL Autosampler
- Injection Capabilities: Supports liquid injection, headspace analysis, and solid-phase microextraction (SPME).
- Sample Handling: Accommodates various vial sizes with automated dilution, mixing, heating, and internal standard addition.
- Injection Volume: Highly precise and adjustable for small to large volumes.
- Efficiency Enhancements:
- Reduces sample variability and rework.
- Automates repetitive tasks to minimize operator error and increase productivity.
5975C MSD Detector
Mass Spectrometer Configuration
- Mode (Standard): Electron Ionization (EI), Positive Chemical Ionization (PCI), Negative Chemical Ionization (NCI), and EI with CI source.
- Ion Source Type: Inert non-coated EI source.
- Quadrupole Mass Filter:
- Monolithic hyperbolic gold-coated quadrupole.
- Heatable to 200 °C for improved stability and reduced contamination.
- Mass Range: 1.6 to 1050 u.
- Mass Resolution: Unit mass, adjustable by tuning.
- Mass Stability: Better than 0.10 u over 48 hours.
Detection and Sensitivity
- Detector Type: Triple-Axis High Energy Diode (HED) Electron Multiplier (EM) Detector.
- Dynamic Range: 10⁶ (electronic).
- Minimum Detectable Levels (MDL):
- EI mode: <24 fg using octafluoronaphthalene (OFN) in SIM mode.
- PCI mode (methane reagent gas): 125:1 S/N for 1 µL injection of benzophenone at 100 pg/µL concentration.
- NCI mode (methane reagent gas): <10 fg using OFN in SIM mode.
Scanning Performance
- Scan Rate: Up to 12,500 u/s (electronic); write-to-disk up to 8,000 u/s.
- SIM Performance: 60 ions x 100 groups; automated SIM setup and synchronous SIM/scan operation.
- Instrument Detection Limit (IDL): Statistically delivered IDL of <24 fg for OFN in EI mode at 99% confidence level.
Temperature Ranges
- Ion Source: 150 to 350 °C.
- Transfer Line: 100 to 350 °C.
- Quadrupole: 106 to 200 °C.
Gas Handling
- Maximum Recommended Flow Rates:
- Performance turbomolecular pump: 4 mL/min.
- Pumping System Options:
- Performance turbomolecular pump (260 L/s).
Automation and Maintenance
- Autotune: Includes gain normalization and one-click tunes for BFB and DFTPP compliance.
- Deconvolution Reporting Software (DRS): Enhances compound identification and reporting.
- Retention Time Locking (RTL): Simplifies method transfer between systems.
- Maintenance Features:
- Removable ion optics (source, filaments, lenses, quadrupole, and detector) within 1 minute.
- Integrated Early Maintenance Feedback (EMF) system for performance tracking.
Integration with Capillary Flow Technology
- Supports advanced features like backflushing, detector splitting, and two-dimensional GC for enhanced chromatographic flexibility.
These detailed parameters ensure the Agilent 5975C GC/MSD delivers unparalleled precision, robustness, and sensitivity across a wide array of analytical applications.
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