Simple on-site extraction and GC-MS analysis of rotenone and degradation products for monitoring invasive fish eradication treatments in fresh and brackish waters

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 9th September 2024? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring to you applications by Agilent Technologies, Shimadzu, and Thermo Fisher Scientific and poster by LECO from ACS meeting!<h4>1. Thermo Fisher Scientific: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_002952_gc_ms_isq_environmental_an002952_na_en_9738609742.pdf">Adhering to U.S. EPA Method 524.2 for the analysis of volatile organic compounds in drinking water</a></h4><ul><li>application</li></ul>Goal: Demonstration of a routine analytical method that meets the requirements outlined in U.S. EPA 524.2 for the quantitation of volatile organic compounds (VOCs) in drinking water, using the Teledyne LABS Tekmar Lumin Purge and Trap (P&amp;T) concentrator paired with the AQUATek LVA autosampler system along with a Thermo Scientific™ ISQ™ 7610 MS system coupled with a Thermo Scientific™ TRACE™ 1610 gas chromatograph (GC) and Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS). Method linearity, method detection limit (MDL), precision, and accuracy were assessed to evaluate method performance.Introduction: Analytical testing labs play a crucial role in monitoring surface, ground, and drinking water for volatile organic compounds (VOCs). Common by-products in the processing of household and industrial products, VOCs can contaminate water sources, potentially harming the environment and public health. To safeguard against this, labs use the U.S. EPA Method 524.21 to test water for the presence of VOCs, including four trihalomethane disinfection by-products. This procedure utilizes Purge and Trap (P&amp;T) procedures to remove VOCs with high volatility and low water solubility from water samples, followed by gas chromatography-mass spectrometry (GC-MS).Conclusion: The TRACE 1610 GC, the ISQ 7610 system, and the Tekmar Lumin P&amp;T with the AQUATek LVA autosampler system together offer benefits for executing U.S. EPA Method 524.2. The Tekmar Lumin P&amp;T concentrator enhances sample throughput through efficient trap cooling and moisture control, thus reducing peak interference and extending GC column life. The ISQ 7610 system’s VPI and ExtractaBrite ion source allow ionization source and analytical column replacement without venting the instrument, ensuring minimal downtime, and the XLXR™ detector offers extended linear dynamic range. The collective technology addresses routine VOC analysis challenges, ensuring robust sensitivity, maximized output, and consistent method compliance. The ISQ 7610 system equipped with the VPI coupled with the Tekmar Lumin P&amp;T and the AQUATek LVA autosampler exceeds all the requirements outlined in U.S. EPA Method 524.2 for analysis of VOCs in drinking water:<ul><li>Excellent linearity for all compounds was demonstrated with the %RSD of the calibration response factors passing all method requirements.</li><li>MDL and precision for seven 0.5 ppb standards showed no interference from excessive water and produced very reproducible results. The average MDL result for all 83 target compounds was 0.06 ppb with a precision of 4.06%.</li><li>The precision for n=31 samples over 189 injections displayed &lt;30% RSD accuracy for all compounds as the method requires. The average precision for all 83 target compounds and 2 surrogates gave a %RSD of 6.43% with an accuracy of 98% recovering the compounds. Individually, 4-bromofluorobenzene and 1,2-dichlorobenzene-d4 had a 7.68% RSD with an accuracy of 98% and 4.95% RSD and an accuracy of 95%, respectively, over 189 injections and almost four days of uninterrupted analysis.</li></ul><h4>2. Shimadzu: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_01_00706_en_f95bd4b605.pdf">Analysis of Denatured Fuel Ethanol with Brevis GC-2050 Using ASTM D5501</a></h4><ul><li>application</li></ul>User Benefits<ul><li>The compact design of the Brevis GC-2050 enables space-saving in the laboratory.</li><li>As an alternative gas for helium, hydrogen can be used as the carrier gas.</li><li>&nbsp;Analysis of ethanol and methanol in fuels based on ASTM D5501 is possible.</li></ul>IntroductionBioethanol has attracted attention as a form of renewable energy which can be obtained from biomasssuch as corn and sugar cane. ASTM D5501 provides a test method for determination of the concentrations of ethanol and methanol in fuels for concentrations of ethanol from 20 to 100 wt% and concentrations of methanol from 0.01 to 0.6 wt%.In this Application News article, measurements of the purity of ethanol containing gasoline as a denaturant as specified in ASTM D5501 were carried out with a Brevis GC-2050 gas chromatograph, using helium and hydrogen asthe carrier gases.ConclusionEthanol purity tests were carried out as provided in ASTM D5501 using a Brevis GC-2050 gas chromatograph. The splitter linearity test showed no inlet discrimination so that accurate qualitative analysis could be made for denatured fuel ethanol with the wide boiling range components regardless of whether helium or hydrogen was used as the carrier gas.<h4>3. Agilent Technologies: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_aldehydes_beer_pal3_autosampler_5977c_gc_msd_5994_7633en_agilent_1fe3b8541c.pdf">Analysis of Aldehydes in Beer by Agilent PAL3 Autosampler and 5977C GC/MSD</a></h4><ul><li>application</li></ul>AbstractThis application note describes a method for quantitation of four aldehydes (hexanal, furfural, phenylacetaldehyde, and trans-2-nonenal) responsible for off-flavors in beer using an Agilent 8890/5977C GC/MSD with an Agilent PAL3 (SPME) autosampler. The method used fully automated, solvent-free extraction and on-fiber derivatization. The aldehyde compounds were derivatized with the derivatization agent O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine hydrochloride (PFBHA) using the on-fiber derivatization procedure. The derivatization agent was first adsorbed onto an Agilent 65 µm PDMS/DVB fiber. Next, the fiber was inserted into a 20 mL headspace vial containing a 2 mL beer sample with agitation at 60 °C for 30 minutes. Both extraction and derivatization procedures were automatically performed using the PAL3 autosampler. The method demonstrated excellent sensitivity, with detection limits of 0.0009 µg/L for hexanal, 0.52 µg/L for furfural, 0.015 µg/L for phenylacetaldehyde, and 0.003 µg/L for trans-2-nonenal. The limits of the quantification for the four compounds were 0.003, 1.72, 0.05, and 0.01&nbsp;µg/L, respectively. The four aldehydes were successfully quantified in four beer samples purchased from a supermarket. Good repeatability was demonstrated with RSD &lt; 4.9% based on three replicate injections of the four beer samples for all four&nbsp;aldehydes.ConclusionThis application note describes the quantitative analysis of four aldehydes (hexanal, furfural, phenylacetaldehyde, and trans-2-nonenal) responsible for off-flavors in beer using an Agilent 8890/5977C GC/MSD with a PAL3 (SPME) autosampler. This method offers the advantages of full automation, rapid analysis, solvent-free extraction, and on-fiber derivatization. With this automated solution, excellent sensitivity was demonstrated for the detection of hexanal (0.0009 μg/L), furfural (0.52 μg/L), phenylacetaldehyde (0.015&nbsp;μg/L), and trans-2-nonenal (0.003 μg/L). Four different brands of beer were analyzed, with hexanal detected in the range of 0.45 to 1.56 μg/L, furfural in the range of 6.62&nbsp;to 50.37 μg/L, phenylacetaldehyde in the range of 6.64 to 10.51&nbsp;μg/L, and trans-2-nonenal in the range of 0.031 to 0.062&nbsp;μg/L. Good repeatability was demonstrated with RSD&nbsp;&lt;&nbsp;4.9% based on three replicate injections of the four beer samples for all four aldehydes.<h4>4. LECO: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/hf_acs21_lpss_284_c35134b9cd.pdf">Combining GC with MS and Olfactory Detection for a Variety of Food, Flavor, and Fragrance Analyses</a></h4><ul><li>Poster / ACS</li></ul>INTRODUCTIONGas chromatography (GC) coupled with mass spectrometry (MS) is an important tool for the characterization of a wide range of food, flavor, and fragrance samples. The components most likely to contribute to the aroma of a sample tend to be volatile and semi-volatile analytes, and GC-MS is well-suited for this type of analysis. Complex samples are effectively separated into the individual analyte components with GC. Time-of-Flight (TOF) MS detection provides important information towards the identification of these potentially important components of the sample with full m/z range data that can be library searched and that is also optimal for deconvolution algorithms. The incorporation of olfactory (O) detection with this data is particularly helpful for connecting the identified features with their contributions to the overall aroma or flavor. This type of sensory directed analysis highlights regions of interest and leads to specific analytes of interest for a focused review of the data. This combination of tools can separate and identify analytes and then determine those that are most important for contributing to the sensory characteristics of the sample. A variety of samples were analyzed with this combination of tools, and the benefits of using the information together are highlighted.CONCLUSIONSIn this work, the combination of a GC separation with MS and O for detection provided a powerful and efficient analytical platform to isolate individual analytes, identify those isolated analytes, and connect them to their sensory impacts. The olfactory data allowed for sensory directed analysis. In each case, the GC separation and full m/z range TOFMS data were crucial for determining the identification of the feature responsible for the characteristic aroma. This collection of tools was demonstrated for the characterization of the most aroma impacting components of a nutmeg essential oil, the distinction of sensory differences in cilantro, and the determination of an off-odor in beer.

News from LabRulezGCMS Library - Week 37, 2024

Comprehensive methodology for semi-volatile organic compound determination in ambient air with emphasis on polycyclic aromatic hydrocarbons analysis by GC–MS/MS

In the week from September 23, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars">👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</a></h4></blockquote><blockquote>👉 Search and filter in the largest global database with over 3 500 GC, LC, MS and spectroscopy webinars.</blockquote><h5>1.&nbsp;Mettler-Toledo: Automated Data Management for LC/GC Workflows</h5><ul><li>Mo, 23.9.2024 10:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4226">Registration</a></li></ul>How can you support digitalized and scalable sample preparation processes for better chromatography results.<h5>2. Agilent Technologies: PFAS in Food Supply Chains: Regulations and Analytical Approaches: in association with AOAC India Section</h5><ul><li>Tu, 24.9.2024 08:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4281">Registration</a></li></ul>PFAS characteristics and the challenges they present to food safety.<h5>3. Waters Corporation: Chromatography - APGC</h5><ul><li>Tu, 24.9.2024 15:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4307">Registration</a></li></ul>Discover the advantages of GC coupled to MS under atmospheric pressure (Atmospheric Pressure GC/ APGC) as a powerful alternative to electron ionization (EI) for GC-MS.<h5>4. Agilent Technologies: Alcoholic Beverages Virtual Symposium: Wine</h5><ul><li>Tu, 24.9.2024 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4259">Registration</a></li></ul>How you can assure safety, authenticity, and quality of alcoholic beverages.<h5>5. Waters Corporation: General Sample Preparation</h5><ul><li>We, 25.9.2024 09:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4308">Registration</a></li></ul>Join us in exploring SPE key parameters and best practices for implementing successful SPE methods.<h5>6. Waters Corporation: Automated Sample Preparation</h5><ul><li>We, 25.9.2024 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4309">Registration</a></li></ul>The Andrew+™ pipetting robot offers fully automated liquid handling using electronic pipettes and labware holders.<h5>7. Agilent Technologies: Sample Cleanup: Method Development for Solid Phase Extraction and Beyond</h5><ul><li>We, 25.9.2024 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/3917">Registration</a></li></ul>We’ll discuss tips for selecting, developing, and implementing SPE methods. We’ll also discuss newly developed targeted filtration options and their benefits.<h5>8. LECO: Non-Targeted Screening in Sustainable Fuels: Exploring Method Development and Fuel Quality Assessment Using GCxGC-MS and Hyphenated Techniques</h5><ul><li>Th, 26.9.2024 14:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4296">Registration</a></li></ul>Embark on a journey of discovery in chemical analysis, with each instalments of our monthly webinar series delivering fresh perspectives and invaluable insights.

Webinars LabRulezGCMS Week 39/2024

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 16th September 2024? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring to you applications and other documents by Agilent Technologies, Shimadzu, Thermo Fisher Scientific, and LECO!<h4>1. Shimadzu: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/c146_e452_c8a53d60a2.pdf">Database for GC-MS(/MS) Aroma Analysis - Smart Aroma Database</a></h4><ul><li>Brochure</li></ul>Provides Efficient and Accurate Aroma Analysis Using GC-MS(/MS)Information on more than 500 compounds that contribute to aroma is registered in Smart Aroma Database™, enabling the objective evaluation and analysis of aroma compounds using GC-MS(/MS).1. Automatically Detects Aroma Compounds from Scan Measurements with High Accuracy2. Easily Narrows Down the Compounds that Contribute to the Aroma3. Enables High-Sensitivity Target Analysis Using MRM and SIM4. Supports a Variety of Systems<h4>2. Agilent Technologies: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/br_5q_gc_column_campaign_5994_7596en_agilent_baca38e505.pdf">Agilent J&amp;W DB-5Q and HP-5Q GC columns</a></h4><ul><li>Brochure</li></ul><h5>Get the Most from Your MS</h5>As mass spectrometry continues to push the boundaries of sensitivity and speed, you need a column that can do the same<ul><li>Agilent J&amp;W 5Q GC columns are designed to ensure optimal analyte delivery to your quadrupoles. They combine industry-leading ultra inert performance with ultra low-bleed technology, setting a new standard for GC/MS column reliability and productivity.</li><li>Ultra low-bleed performance enhances data accuracy with high spectral fidelity and stable baseline integration.</li><li>Ultra inert performance increases sensitivity for active, trace-level analytes and provides balanced deactivation for multiclass analyte panels.</li><li>Ultrafast conditioning and outstanding column durability improve uptime by minimizing the frequency of column changes.</li><li>Identical selectivity to current 5ms columns simplifies adaptation to existing retention time libraries and retention time locking.</li><li>Compatibility with any GC/MS system ensures a seamless fit for all Agilent GC platforms. Agilent J&amp;W 5Q GC columns are available in high-efficiency, hydrogen-compatible, and backflushing dimensions.</li></ul><h4>3. Thermo Fisher Scientific: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/AN_002784_Improvements_for_the_analysis_of_volatile_VOC_and_very_volatile_VVOC_organic_compounds_using_In_Tube_Extraction_Dynamic_Headspace_ITEX_DHS_and_cryogen_free_refocusing_4_bd362df5a5.pdf">Improvements for the analysis of volatile (VOC) and very volatile (VVOC) organic compounds using In-Tube Extraction-Dynamic Headspace (ITEX-DHS) and cryogen-free refocusing</a></h4><ul><li>Application</li></ul>GoalTo demonstrate how the technological development of dynamic headspace extraction/enrichment techniques, such as ITEX-DHS (In-Tube Extraction-Dynamic Headspace) coupled to a cryogen-free refocusing in the PTV injector, enables the achievement of lower detection limits for volatile and very volatile organic compounds.IntroductionVolatile organic compounds (VOCs) are a group of organic chemicals with low vapor pressure that can easily evaporate into the air, even at room temperature. These compounds can originate from various sources, including industrial processes, vehicle emissions, and natural sources. While VOCs are often associated with air pollution, they can also contaminate water, thus posing potential risks to human health and the environment.1 VOCs can enter water through direct discharges, atmospheric deposition, or runoff from contaminated areas. Common VOCs found in water include benzene, toluene, ethylbenzene, and xylene (BTEX), as well as chlorinated compounds such as trichloroethylene (TCE) and tetrachloroethylene (PCE). These compounds can cause adverse health effects, ranging from short-term irritation to long-term chronic conditions, depending on the concentration and duration of exposure.Regulatory authorities all over the world have established limits to control the maximum amount of VOCs in drinking water, groundwater, or surface water (e.g., Safe Drinking Water Act (SDWA) in the USA or the European Directive 2008/105/EC).2,3 Therefore, monitoring and analyzing VOCs in water play crucial roles in identifying and addressing potential contamination issues, guiding remediation efforts, and ensuring compliance with water quality regulations.4Common methods to analyze VOCs in water include headspace, purge and trap, solid-phase microextraction, and liquid-liquid extraction as possible sample preparation techniques employed to extract and concentrate VOCs before GC-MS analysis. As technology advances, continuous improvements in analytical methods and instrumentation contribute to more accurate and efficient VOC analysis, enhancing the ability to safeguard water resources and public health.When dealing with drinking water testing, the limits of detection are particularly challenging, requiring an efficient enrichment before GC-MS analysis.In-Tube Extraction-Dynamic Headspace (ITEX-DHS) is a sample preparation technique for the extraction and preconcentration of volatile compounds from different matrices, such as water, soil, or biological samples. One of the key advantages of ITEX-DHS is its high sensitivity and selectivity for volatile compounds. It allows for the extraction of low concentrated analytes from complex matrices while minimizing interference from non-volatile matrix components. Additionally, the technique offers an automated and efficient sampling process through a robotic autosampler, making it suitable for unattended and time-sensitive analyses.ITEX-DHS has found applications in various fields, including environmental monitoring, food analysis, and forensic science. Its versatility makes it particularly valuable in situations where trace-level analysis of volatile compounds is crucial. An example of the use of ITEX-DHS for the detection of odorants in water at ng/L level is reported in a previous application note.5In this study, the performance of the ITEX-DHS sampling technique has been evaluated for trace level detection of volatile and very volatile compounds (VVOCs) in water, in combination with peak refocusing into a Programmed Temperature Vaporizer (PTV) injector, to enhance peak shape and signal-to-noise ratio.<h4>4. LECO: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/PEGBTX_EXPAND_YOUR_PFAS_ANALYSIS_203_821_689_d24746e8bb.pdf">Expand Your PFAS Analysis - Screen for Targets and Identify Unknowns Simultaneously</a></h4><ul><li>Application</li></ul>Key Words: PFAS, GC-MS, HR-MS, TOFMS, Environmental Analysis, Pollutants, Emerging Substances, Non-target, NTS, ScreeningBackground and DescriptionResearch into the prevalence of er- and polyfluoroalkyl substances (PFAS)—also known as “forever chemicals” due to theirp high stability in our environment and food chain continues to grow. At the same time, regulatory control of these species in our water and food supplies continues to gain momentum. However, analysis of PFAS in complex environmental samples can be challenging due to the enormous number and variety of PFAS chemicals. New analytical methods must be developed to monitor PFAS in the environment.This application focuses on the rapidly expanding area of PFAS analysis and highlights how screening for known PFASnote targets, as well as discovering and identifying unknown PFAS chemicals, can be performed using high-performance GC-TOFMS. New libraries are being developed to facilitate the screening of these pollutants in samples.ConclusionMeeting the growing environmental research and regulatory needs for PFAS analysis requires the use of powerful technologies to screen for known targets and to detect and identify unknown PFAS candidates. Here, sub-nominal mass GC-TOFMS, allowed simultaneous, full mass range, highly sensitive target, and NTS screening for PFAS in Anti-Fog/Demisting products, detecting a variety of both known PFAS and unknown PFAS candidates. The use of accurate mass GC-HR-TOFMS technology with EI and CI capabilities facilitated strong tentative identifications of the unknowns to be a class of fluorotelomer ethoxylates (FTEOs). This approach, together with the results obtained, suggests these technologies are an ideal choice for screening and identification of volatile and semi-volatile PFAS, in an array of sample types in complex matrices.

News from LabRulezGCMS Library - Week 38, 2024

In the week from September 30, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars">👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</a></h4></blockquote><blockquote>👉 Search and filter in the largest global database with over 3 500 GC, LC, MS and spectroscopy webinars.</blockquote><h5>1.&nbsp;Agilent Technologies: Alcoholic Beverages Virtual Symposium: Beer</h5><ul><li>Tu, 1.10.2024 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4262">Registration</a></li></ul>How you can assure safety, authenticity, and quality of alcoholic beverages.<h5>2.&nbsp;C&amp;EN/Metrohm: In-field Identification of Low-Quality Medicines using Handheld Raman</h5><ul><li>Th, 3.10.2024 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4317">Registration</a></li></ul>The global pharmaceutical market's growth has led to an alarming increase in substandard and falsified (SF) medicines, posing significant risks to public health.<h5>3.&nbsp;Waters Corporation: ICYMI (In Case You Missed It) - Empower Hot Topics from [inform] 2024</h5><ul><li>Th, 3.10.2024 19:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4302">Registration</a></li></ul>Best practices and essential tools for reviewing data and audit trails in Empower.

Webinars LabRulezGCMS Week 40/2024

GC×GC-TOFMS Analysis of Fecal Metabolome Stabilized Using an At-Home Stool Collection Device

Our Library never stops expanding. What are the most recent contributions to LabRulezGCMS Library in the week of 23rd September 2024? Check out new documents from the field of the gas phase, especially GC and GC/MS techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT GCMS AND RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">LabRulezICPMS</a> libraries.</blockquote>This week we bring to you applications by Agilent Technologies, Shimadzu, Thermo Fisher Scientific, and a presentation by LECO!<h4>1. Shimadzu: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_09_SSK_019_en_5e1bde719c.pdf">Analysis of Epichlorohydrin in Water using HS- GC/MS</a></h4><ul><li>Application</li></ul>User Benefits<ul><li>Water samples can be analyzed with a simple preparation.</li><li>Using a headspace autosampler, the analysis of epichlorohydrin in water quality can be performed conveniently.</li></ul>IntroductionEpichlorohydrin (ECH) is primarily used in the production of various resins (epoxy, ion exchange, etc.) and synthetic glycerin. Additionally, it is used as a stabilizer for carbon containing products in surfactants, plasticizers, dyes, and pharmaceuticals1). Some studies have demonstrated that damage to the nasal passages, respiratory tract and kidneys occurred in rodents exposed to epichlorohydrin. It has been observed that exposure to ECH induced a high nasal cancer response in rats, therefore, the United States Environmental Protection Agency (EPA) has classified epichlorohydrin as a “probable” human carcinogen (Group B2).According Water Pollutants of Water Environment Conservation Act, the permissible discharge limits of ECH in water were 0.03 to 0.3 mg /L by the classified area. The test method for ECH analysis in water is "Epichlorohydrin-Solvent Extraction/Gas Chromatography-Mass Spectrometry (ES 04608.1)" as the official test method of water pollution.2)The ES 04608.1 was used to extraction method with a large volume of solvent, it caused high consumption of solvent and long time of preparation. To solve these disadvantages, analysis of ECH in water in this application was performed using HS-20 NX headspace sampler without sample pretreatment.This application demonstrates the validation of a method for analysis of ECH in water samples using HS-GC/MS (Fig. 1) to meet the demanded levels of ES 04608.1 in Korea.ConclusionsThis Application news demonstrated the use of a Shimadzu GCMS-QP2020 NX coupled HS-20 NX for measurement of ECH in water. The proposed analytical method was with good validation parameters, such as linearity, MDL, LOQ, accuracy and precision which was satisfied the criteria of standard method (ES 04608.1) in Korea.<h4>2. Agilent Technologies: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_ethylene_oxide_2_chloroethanol_8890_7010_gcms_5994_7720en_agilent_337dc4394d.pdf">Estimation of Ethylene Oxide and 2-Chloroethanol in Spices and Oilseeds Using QuEChERS Extraction and GC/MS/MS</a></h4><ul><li>Application</li></ul>AbstractThis application note demonstrates the use of an Agilent 8890 GC system coupled with an Agilent 7010 GC/MS triple quadrupole mass spectrometry system to detect and quantify ethylene oxide (EtO) and 2-chloroethanol (2-CE) simultaneously in foodstuffs such as flaxseed, cumin powder, and red chili powder. Sample preparation was done using QuEChERS extraction and a dispersive cleanup process followed by injection into GC/MS/MS through liquid injection. A limit of quantification (LOQ) of 10 ppb for both compounds was achieved in matrix. Average recoveries ranged from 75 to 86% for both compounds.IntroductionEtO is used to sterilize foods to eliminate insects and bacteria, such as salmonella. Ethylene chlorohydrin, or 2-CE, is a derivative produced by the reaction of EtO with chlorine ions present in foodstuff. Use of EtO is banned in the European Union (EU) due to its carcinogenic and toxic properties.Previously, methods for analysis of EtO (EtO and 2-CE) have been developed that include acidic conversion of EtO to 2-CE. These methods are time-consuming, labor-intensive, and require large quantities of harmful solvents. Due to the volatile nature of EtO, sample preparation is crucial. In December 2020, the EU Reference Laboratories (EURL) for Residues of Pesticides recommended a single-residue method for the analysis of EtO and 2-CE in sesame seeds using QuEChERS extraction followed by GC/MS/MS analysis. The method adopted in this work demonstrates the use of an automated liquid sampler for sample introduction to the 8890 GC system coupled with a 7010 GC/MS triple quadrupole mass spectrometry system.ConclusionAn accurate and rugged method was developed which meets the requirements of the EURL for a single-residue method that uses QuEChERS extraction followed by GC/MS/MS analysis for the analysis of EtO and 2-CE in flaxseed, cumin powder, and red chili powder. The LOQ of the method was demonstrated at 10 ng/g for all the tested matrices. Repeatable results are found for 6 successive replicates of matrix-based standards at 10 ng/g concentration levels for EtO and 2-CE. Excellent recoveries were obtained for both EtO and 2-CE in all tested matrices at 20 and 50 ng/g spiked concentration levels. Thus, this study demonstrates the usefulness of the developed method for the routine analysis of food samples for EtO and 2-CE at trace levels.<h4>3. Thermo Fisher Scientific: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/An_advanced_integrated_GC_MS_MS_and_LC_MS_MS_workflow_for_the_comprehensive_analysis_of_pesticide_residues_in_food_a5878f2c6b.pdf">An advanced integrated GC-MS/MS and LC-MS/MS workflow for the comprehensive analysis of pesticide residues in food</a></h4><ul><li>Application</li></ul>GoalAnalysis of proficiency test (PT) samples to demonstrate the benefits of combining GC-MS/MS and LC-MS/MS with the innovative Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) for improving laboratory efficiency in the analysis of multi-class pesticide residues in food.Keywords: Pesticide residues analysis, comprehensive pesticides workflows, QuEChERS, LC-MS/MS, GC-MS/MS, Chromeleon CDS, cross-confirmation, targeted quantitation, automated data review.BackgroundAccording to the World Health Organization, more than one thousand different pesticides are used to protect crops from pests to increase crop yields and to minimize deterioration of agricultural products during post-harvest storage and transportation. However, inappropriate use of pesticides can result in contamination of the food supply, making it essential to define and monitor pesticide residue targets to protect consumer health, support trade, and establish food regulatory control.1Consequently, laboratories are tasked to develop methods to detect, correctly identify, and quantitate hundreds of different pesticides and their transformation products in hundreds of different sample matrices, in compliance with Maximum Residue Levels (MRLs) set by regulatory bodies.Data analysis of pesticide residues in food typically requires numerous performance checks including retention time, ion ratios, calibration curves, recovery, and precision. Data review of thousands of data values in a single chromatographic run and checking compliance against quality control criteria such as the EC SANTE guidelines2 are some of the most time-consuming tasks in pesticides analysis.Therefore, it is essential that workflows cover a broad pesticides scope, are sensitive and robust, and are as productive and efficient as possible to achieve compliance with regulations while meeting business goals such as return on investment (ROI), sample turnaround times, and cost-per-sample targets.An innovative approachIn response to this challenge, new pre-configured “out of the box” pesticide workflows based on the latest Thermo Scientific™ GC-MS/MS and LC-MS/MS instruments and Chromeleon CDS 3 have been specifically designed for multi-class pesticides analysis.These solutions include the hardware, software, built-in instrument acquisition methods, and customizable data processing methods including view settings and report templates, along with details of sample extraction and consumables for fast implementation.This new approach, which enables the detection, identification, and quantitation of up to 700 pesticides by GC-MS/MS and LC-MS/MS, combines results in a unique software user interface to confirm the identity of residues quickly and accurately, especially those amenable by both techniques.This automated cross-confirmation increases confidence in the data by minimizing the risk of false positive and false negative results while increasing productivity by reducing the need for repeat sample injections when either the LC-MS/MS or GC-MS/MS analysis is subject to interference. This is especially the case for more difficult samples that contain high amounts of matrix co-extractives.Proof statementLaboratories are often required to undertake blind analysis of PT samples containing an unknown number of unspecified pesticides. Assessing PT samples is an independent and more realistic test of the laboratory’s methods and procedures.In this application brief, the analysis of PT samples was undertaken to evaluate the analytical performance of the new integrated GC-MS/MS and LC-MS/MS pesticides workflow and to illustrate the benefits of the new software features.<h4>4. LECO: <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/O_12_Characterization_and_Quantitative_Hydrocarbon_Group_Type_Analysis_of_Plastic_Derived_Pyrolysis_Oils_by_G_Cx_GC_TOFMS_FID_0a253a5d5e/O-12-Characterization-and-Quantitative-Hydrocarbon-Group-Type-Analysis-of-Plastic-Derived-Pyrolysis-Oils-by-GCxGC-TOFMS-FID.pdf">Characterization and Quantitative Hydrocarbon Group-Type Analysis of Plastic-Derived Pyrolysis Oils by GCxGC-TOFMS/FID</a></h4><ul><li>Presentation / <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/218">MDCW</a></li></ul>Outline<ul><li>Pyrolysis Oils Characterization Workflow</li><li>Plastic-Derived Pyrolysis Oil Samples</li><li>Choosing a GCxGC system</li><li>Benefits of the Pegasus BT 4D MS</li><li>Benefits of the Paradigm Shift System</li><li>Choosing a GCxGC column set…</li><li>Mapping out the GCxGC Space</li><li>Group-Type Analysis of Pyrolysis Oils</li><li>ChromaTOF TILE</li><li>Areas of Interest + PCA</li><li>Comparing Trends of Multiple Features</li><li>Benefits of the Pegasus HRT+ 4D</li><li>Benefits of the Multi-Mode Source (MMS)</li><li>Pegasus HRT+ 4D Data Processing Workflows</li><li>High-Resolution, Accurate Mass Data</li><li>Mass Defect: Nitrogen-Containing Species</li><li>Mass Defect: Sulfur-Containing Species</li><li>Leveraging High Resolution Mass Accuracy</li><li>Conclusion</li></ul>

News from LabRulezGCMS Library - Week 39, 2024

Broadband Laser-Based Infrared Detector for Gas Chromatography

In the week from October 7, the following webinars await you in the field of gas / solid phase and especially Raman, FTIR, GC and GC/MS.<blockquote><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinars">👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</a>👉 Search and filter in the largest global database with over 3 500 GC, LC, MS and spectroscopy webinars.</blockquote><h5>1. Agilent Technologies: MassHunter Acquisition Q-TOF Part I – Basic Overview</h5><div><div><ul><li><div>Tu, 8.10.2024 14:00 CEST</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4342">Registration</a></div></li></ul></div>Join us for an insightful webinar where we delve into the essentials of MassHunter Acquisition Q-TOF.</div><h5>2. Agilent Technologies: Unleash the Power of Small - Agilent New 8850 GC System</h5><ul><li>We, 9.10.2024 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4328">Registration</a></li></ul><div>How to maximize productivity, efficiency, and uptime.</div><h5>3. Agilent Technologies: Get the Most Out of Your MS</h5><div><div><ul><li><div>Fr, 11.10.2024 11:00 CEST</div></li><li><div><a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/webinar/4333">Registration</a></div></li></ul></div>Get the most out of your mass spectrometer using the new DB-5Q and HP-5Q columns.</div>

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Broadband Laser-Based Infrared Detector for Gas Chromatography

Webinars LabRulezGCMS Week 41/2024

News from LabRulezGCMS Library - Week 39, 2024

GC×GC-TOFMS Analysis of Fecal Metabolome Stabilized Using an At-Home Stool Collection Device

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Comprehensive methodology for semi-volatile organic compound determination in ambient air with emphasis on polycyclic aromatic hydrocarbons analysis by GC–MS/MS

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Simple on-site extraction and GC-MS analysis of rotenone and degradation products for monitoring invasive fish eradication treatments in fresh and brackish waters

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