From the Leader in Spectral Data
KnowItAll offers solutions to identify, analyze, and manage your MS data. Combined with Wiley’s comprehensive, high-quality spectral reference databases, it provides one of the most advanced technologies available for fast, reliable spectral analysis.
With the NEW KnowItAll 2024, Wiley continues to expand KnowItAll’s MS capabilities with updates to accelerate analysis workflows even further, plus a new optional tool for quantitative analysis.
By combining all the tools and data you need for effective MS analysis into a single, easy-to-use interface, KnowItAll will save you time, improve workflow, and increase your ability to reach conclusions from your data.
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GC-MS data analysis can be time consuming, especially when examining complex analytes. The new MS Expert automatically processes, deconvolutes, and analyzes GC-MS data.
Combined with KnowItAll’s fast database search, it accurately suggests matches to knowns and allows unknowns to be further examined.
Wiley: Wiley KnowItAll Solutions for MS. Whether you’re an expert or beginner, this new MS technology from Wiley can save you hours of manual analysis time by combining fast, flexible deconvolution with an integrated reference database search into a single, automated workflow to identify components.
Simply import a GC-MS data file and the software automatically deconvolutes the TIC into components. All extracted component MS spectra are then automatically searched against reference libraries* to find matches. Results are shown as a hit list for each component.
Unidentified components or components with low match scores can then be sent to KnowItAll’s SearchIt tool for manual investigation. In SearchIt, one can use adaptive search to match similar components or use mixture analysis to separate coeluted components.
Wiley offers sophisticated tools to search and compare unknown mass spectra with KnowItAll’s high-quality reference spectra* or user generated databases.
With fast search speeds, powerful algorithms, and advanced technologies, Wiley aims to deliver results you can rely on.
Tools That Set KnowItAll Apart
NEW! Wiley’s Patent-Pending Adaptive Search for MS:
This technology finds spectral matches that are similar to the unknown but have additional or missing selective fragment(s). It then suggests what might be causing the differences, where possible. This feature provides tremendous insight into structural possibilities to explore when there is no exact match. Ultimately, this may lead to more intelligent and confident identification and confirmation.
Mixture Analysis of MS Spectra:
One of the most powerful features is KnowItAll’s ability to analyze mixtures. When searching an unknown against a reference database, you can choose to search for multiple components. The result is a series of composite spectra, each accompanied by the individual component spectra that comprise the composite spectrum, as well as the residual spectrum (difference between the query and the composite spectrum). Composite spectra are then ranked by how closely they resemble the query spectrum.
With ProcessIt, users can view and select a mass spectrum or the average of mass spectra and define the background. The selected mass spectrum or extracted spectra can be transferred for database searching or imported into a user database.
To empower researchers, KnowItAll 2024 revamps manual GC-MS processing to provide users greater control of component separation and identification. These improvements, combined with the completely automated data analysis in the previous release, make KnowItAll 2024 an even more reliable, efficient, powerful, and accurate tool for GC-MS data analysis.
Wiley: Wiley KnowItAll Solutions for MS - GCMS-ProcessIt
Because Wiley Science Solution’s primary business is spectral databases, KnowItAll is built through years of experience in doing just that—building databases.
Researchers can build searchable databases that include one or more analytical techniques (IR, MS, Near IR, NMR, Raman, UV-Vis), chemical structures, and other meta data. So even if a laboratory’s instruments come from multiple manufacturers, KnowItAll can archive the data.
Because structures are critical to your work, we included all the tools you need to streamline your workflow and save time.
ChemWindow is the software chemists worldwide choose for chemical structure drawing. It provides an advanced set of drawing tools that’s easy to use— just click and drag to draw any chemical structure. Access the most comprehensive set of tools to draw rings, bonds, atoms, electrons, charges, chains, arrows, and more.
And with KnowItAll’s ReportIt tool, create standard reports, papers, and presentations that include annotations, tables of data, spectra, 2D and 3D structures, and more.
Spectral Analysis software is not complete without a high-quality database of reference spectra. And with KnowItAll, Wiley offers the best of both!
The KnowItAll Wiley Mass Spectral Library* is a trusted data source that provides over 934,000 mass spectra of the highest quality.
Increase access to over 1.3 million spectra by adding NIST and other MS subscription options!
Wiley’s KnowItAll has always helped us answer the question of “what” is the identify of a substance. And now, with the 2024 release, KnowItAll will now be able to help us answer the question of “how much” of the substance there is with an integrated quantitation tool* to complete and simplify your analytical workflow.
Because all the tools and techniques are integrated into a single environment, KnowItAll makes the laboratory workflow seamless.
For file formats supported, visit sciencesolutions.wiley.com/compatibility
